Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Sugyeong Ha"'
Autor:
Jeongwon Kim, Sugyeong Ha, Minjung Son, Doyeon Kim, Mi-Jeong Kim, Bumseok Kim, Donghwan Kim, Hae Young Chung, Ki Wung Chung
Publikováno v:
Cell Communication and Signaling, Vol 21, Iss 1, Pp 1-16 (2023)
Abstract Background Toll-like receptor 7 (TLR7) is an endosomal TLR activated by single-stranded RNA, including endogenous microRNAs. Although TLR7 is known to promote inflammatory responses in pathophysiological conditions, its role in renal fibrosi
Externí odkaz:
https://doaj.org/article/2b9504b9e1ca4fa0921e5c62a3174905
Autor:
Jeongwon Kim, Jieun Lee, Dahye Yoon, Minjung Son, Mi-Jeong Kim, Sugyeong Ha, Doyeon Kim, Ji-an Yoo, Donghwan Kim, Hae Young Chung, Hyung Ryong Moon, Ki Wung Chung
Publikováno v:
Antioxidants, Vol 12, Iss 11, p 1947 (2023)
Chronic kidney disease (CKD) is a kidney structure and function abnormality. CKD development and progression are strongly influenced by oxidative stress and inflammatory responses, which can lead to tubulointerstitial fibrosis. Unfortunately, there a
Externí odkaz:
https://doaj.org/article/c2104f4e5bd74a75aa70f8887fa9d6eb
Autor:
Dae Hyun Kim, Ye Ra Kim, EunJin Bang, Sugyeong Ha, Sang Gyun Noh, Byeong Moo Kim, Seong Ho Jeong, Hee Jin Jung, Ji Young Lee, Hae Young Chung
Publikováno v:
Endocrinology and Metabolism, Vol 36, Iss 1, Pp 171-184 (2021)
Background Protease-activated protein-2 (PAR2) has been reported to regulate hepatic insulin resistance condition in type 2 diabetes mice. However, the mechanism of lipid metabolism through PAR2 in obesity mice have not yet been examined. In liver, F
Externí odkaz:
https://doaj.org/article/0d855c34e9b4421f85ee925a14806f39
Autor:
Minjung Son, Ga Young Kim, Yejin Yang, Sugyeong Ha, Jeongwon Kim, Doyeon Kim, Hae Young Chung, Hyung Ryong Moon, Ki Wung Chung
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 5, p 4882 (2023)
The peroxisome proliferator-activated receptor (PPAR) nuclear receptor has been an interesting target for the treatment of chronic diseases. Although the efficacy of PPAR pan agonists in several metabolic diseases has been well studied, the effect of
Externí odkaz:
https://doaj.org/article/78dc0b88041942e9a8de17cca616b659
Autor:
EunJin Bang, Sang-Gyun Noh, Sugyeong Ha, Hee Jin Jung, Dae Hyun Kim, A Kyoung Lee, Min Kyung Hyun, Dongwan Kang, Sanggwon Lee, Chaeun Park, Hyung Ryong Moon, Hae Young Chung
Publikováno v:
Molecules, Vol 23, Iss 12, p 3307 (2018)
Tyrosinase is a key enzyme in melanin synthesis, catalyzing the initial rate-limiting steps of melanin synthesis. Abnormal and excessive melanin synthesis is the primary cause of serious skin disorders including melasma, senile lentigo, freckles, and
Externí odkaz:
https://doaj.org/article/be8cf39cd9dc4f9e811f15d943447dbf
Autor:
Sugyeong, Ha, Yejin, Yang, Jeong Won, Kim, Minjung, Son, Doyeon, Kim, Mi-Jeong, Kim, Dong-Soon, Im, Hae Young, Chung, Ki Wung, Chung
Publikováno v:
The Journals of Gerontology: Series A. 78:60-68
The age-associated functional decline of the kidney is accompanied by structural changes including glomerular sclerosis and interstitial fibrosis. Aging kidneys also exhibit increased vulnerability in stressful environmental conditions. In this study
Publikováno v:
Archives of Pharmacal Research. 45:159-173
Renal fibrosis is defined by excessive extracellular matrix (ECM) accumulation and is associated with a decreased kidney function. Increased inflammation and infiltration of inflammatory cells are the key features of renal fibrosis development; howev
Autor:
Ji Young Lee, Hee Jin Jung, EunJin Bang, Hae Young Chung, Byeong Moo Kim, Sang Gyun Noh, Ye Ra Kim, Dae Hyun Kim, Sugyeong Ha, Seong Ho Jeong
Publikováno v:
Endocrinology and Metabolism
Endocrinology and Metabolism, Vol 36, Iss 1, Pp 171-184 (2021)
Endocrinology and Metabolism, Vol 36, Iss 1, Pp 171-184 (2021)
Background: Protease-activated protein-2 (PAR2) has been reported to regulate hepatic insulin resistance condition in type 2 diabe tes mice. However, the mechanism of lipid metabolism through PAR2 in obesity mice have not yet been examined. In liver,
Autor:
Ki Wung Chung, Chae Won Jang, Somi Jeong, Dong Soon Im, Hae Young Chung, Yejin Yang, Jeong-Won Kim, Sugyeong Ha
Publikováno v:
Toxicology. 463
Chronic kidney disease (CKD) is characterized by persistent abnormalities in kidney function, accompanied by structural changes. Interstitial fibrosis, characterized by the accumulation of extracellular matrix (ECM) proteins, is frequently detected d
Autor:
Sugyeong, Ha, Yejin, Yang, Byeong Moo, Kim, Jeongwon, Kim, Minjung, Son, Doyeon, Kim, Hak Sun, Yu, Dong-Soon, Im, Hae Young, Chung, Ki Wung, Chung
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease. 1868:166474
A high-fat diet (HFD) is a major risk factor for chronic kidney disease. Although HFD promotes renal injury, characterized by increased inflammation and oxidative stress leading to fibrosis, the underlying mechanism remains elusive. Here, we investig