Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Suguru Morimoto"'
Autor:
Takahito Kawata, Takuya Shimizu, Takero Shindo, Kensuke Fujiwara, Suguru Morimoto, Mitsumasa Watanabe
Publikováno v:
Haematologica, Vol 109, Iss 3 (2023)
Externí odkaz:
https://doaj.org/article/904d05e5df8c4c0a91e95f30f7d4de72
Autor:
Junji Itou, Rei Takahashi, Hiroyuki Sasanuma, Masataka Tsuda, Suguru Morimoto, Yoshiaki Matsumoto, Tomoko Ishii, Fumiaki Sato, Shunichi Takeda, Masakazu Toi
Publikováno v:
iScience, Vol 23, Iss 2, Pp - (2020)
Summary: Mammary ductal dysplasia is a phenotype observed in precancerous lesions and early-stage breast cancer. However, the mechanism of dysplasia formation remains elusive. Here we show, by establishing a novel dysplasia model system, that estroge
Externí odkaz:
https://doaj.org/article/12ed23d1aa764d119b849635754a8ac5
Autor:
Suguru Morimoto, Tadakazu Kondo, Tomohiro Taya, Hidemasa Matsuo, Yukako Teramoto, Chisaki Mizumoto, Junya Kanda, Kouhei Yamashita, Akifumi Takaori-Kondo
Publikováno v:
Annals of Hematology. 101:1129-1132
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::69e58f127cd62ac404a37a459cd97c1c
https://doi.org/10.1007/s00277-022-04825-8
https://doi.org/10.1007/s00277-022-04825-8
Autor:
Suguru, Morimoto, Takero, Shindo, Yuhei, Iga, Mari, Morita, Kimiko, Yurugi, Kenta, Masuda, Toshiyuki, Hori, Masakatsu, Hishizawa, Tadakazu, Kondo, Kohei, Yamashita, Hironori, Haga, Akifumi, Takaori-Kondo
Publikováno v:
[Rinsho ketsueki] The Japanese journal of clinical hematology. 62(12)
In this study, we report a case of a 77-year-old woman who was presented with anemia in the winter of 2002. She was diagnosed with cold agglutinin disease (CAD) and treated with corticosteroids. Further, her hemoglobin levels were maintained between
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::fa1e5da50bfccfbaccc524d6e1b2131f
https://pubmed.ncbi.nlm.nih.gov/35022336
https://pubmed.ncbi.nlm.nih.gov/35022336
Autor:
Fumiaki Sato, Masakazu Toi, Tomoko Ishii, Yoshiaki Matsumoto, Shunichi Takeda, Hiroyuki Sasanuma, Junji Itou, Rei Takahashi, Suguru Morimoto, Masataka Tsuda
Mammary ductal dysplasia is a phenotype observed in precancerous lesions and early-stage breast cancer. However, the mechanism of dysplasia formation remains elusive. Here we show, by establishing a novel dysplasia model system, that estrogen, a fema
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db565627453f583b6af01a2076689a2f
Autor:
Junji Itou, Tomoko Ishii, Masataka Tsuda, Shunichi Takeda, Suguru Morimoto, Masakazu Toi, Hiroyuki Sasanuma, Yoshiaki Matsumoto, Rei Takahashi, Fumiaki Sato
Publikováno v:
SSRN Electronic Journal.
Mammary ductal dysplasia is a phenotype observed in precancerous lesions and early-stage breast cancer. However, the mechanism of dysplasia formation remains elusive. Here we show, by establishing a novel dysplasia model system, that estrogen, a fema
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f63c36f7750d15be0253b414a87ef01c
https://doi.org/10.2139/ssrn.3438373
https://doi.org/10.2139/ssrn.3438373
Autor:
Tomoko Ishii, Yoshiaki Matsumoto, Rei Takahashi, Suguru Morimoto, Hiroyuki Sasanuma, Masakazu Toi, Fumiaki Sato, Shunichi Takeda, Junji Itou, Masataka Tsuda
Publikováno v:
iScience, Vol 23, Iss 2, Pp-(2020)
iScience
iScience
Summary Mammary ductal dysplasia is a phenotype observed in precancerous lesions and early-stage breast cancer. However, the mechanism of dysplasia formation remains elusive. Here we show, by establishing a novel dysplasia model system, that estrogen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e3f8eba6da196d989924813b2a0ee84
https://doi.org/10.1016/j.isci.2020.100821
https://doi.org/10.1016/j.isci.2020.100821
Autor:
Yusuke Kiyooka, Hiroyuki Sasanuma, Andrew D. Cherniack, Ken Tsutsui, Elsa Callen Moreu, Shinichiro Nakada, Hisashi Tanaka, Suguru Morimoto, Haruna Fujiike, André Nussenzweig, Shunichi Takeda, Maminur Rahman, Masataka Tsuda, Junji Itou, Liton Kumar Saha, Masakazu Toi, Shintaro Yamada
Publikováno v:
Proceedings of the National Academy of Sciences. 115
Women having BRCA1 germ-line mutations develop cancer in breast and ovary, estrogen-regulated tissues, with high penetrance. Binding of estrogens to the estrogen receptor (ER) transiently induces DNA double-strand breaks (DSBs) by topoisomerase II (T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::200c0de304b4b253345bc31f46c6f85d
https://doi.org/10.1073/pnas.1803177115
https://doi.org/10.1073/pnas.1803177115
Autor:
Shunichi Takeda, Suguru Morimoto, Hiroyuki Sasanuma, Masataka Tsuda, Heeyoun Bunch, Caroline A. Austin
Publikováno v:
Genes
Genes, Vol 10, Iss 11, p 868 (2019)
Genes, Vol 10, Iss 11, p 868 (2019)
Type II DNA topoisomerase enzymes (TOP2) catalyze topological changes by strand passage reactions. They involve passing one intact double stranded DNA duplex through a transient enzyme-bridged break in another (gated helix) followed by ligation of th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c430a40635b7599a49491fece4f4c42c
https://doi.org/10.3390/genes10110868
https://doi.org/10.3390/genes10110868
Autor:
Hiroyuki Aburatani, Yasuhito Nannya, Yasunobu Nagata, Yasuhide Takeuchi, Niroshan Nadarajah, June Takeda, Torsten Haferlach, Hiroko Tanaka, Tetsuichi Yoshizato, Constance Baer, Yoichi Fujii, Claudia Haferlach, Masahiro Nakagawa, Kenichi Chiba, Yasushi Miyazaki, Wolfgang Kern, Satoru Miyano, Tamara Alpermann, Hideki Makishima, Masashi Sanada, Yuichi Shiraishi, Kenichi Yoshida, Ryosaku Inagaki, Suguru Morimoto, Seishi Ogawa, Genta Nagae, Hiroo Ueno
Publikováno v:
Blood. 132:1799-1799
MDS is a heterogeneous group of myeloid neoplasms caused by genetic and epigenetic alterations. During the past decade, the major driver mutations in MDS have been fully investigated. However, the role of epigenetic alterations, particularly those of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::96c073991c7644479969251df931f9c6
https://doi.org/10.1182/blood-2018-99-116489
https://doi.org/10.1182/blood-2018-99-116489