Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Suguru Hibino"'
Autor:
Jean A. Engbring, Hynda K. Kleinman, Suguru Hibino, Motoyoshi Nomizu, Masahiko Shibuya, Mayumi Mochizuki
Publikováno v:
Cancer Research. 64:4810-4816
The laminin α5 chain is a component of laminin-10 (α5β1γ1) and -11 (α5β2γ1). In this study, we have screened 113 overlapping synthetic peptides from the laminin α5 globular domain (G-domain) for cell attachment activity with B16-F10 cells usi
Autor:
Masahiro Ando, Michiya Nara, Akinobu Yoshimura, Tetsuya Okano, Masahiro Seike, Hideki Mizutani, Masahiko Shibuya, Futoshi Kurimoto, Kunihiko Kobayashi, Akihiko Gemma, Gaku Moriyama, Shoji Kudoh, Suguru Hibino
Publikováno v:
Lung Cancer. 44:121-127
Purpose: Weekly administrations of CPT-11 plus cisplatin together with an anti-diarrheal program, the Oral Alkalization and Control of Defecation [ Int J Cancer 1999;83:491; Int J Cancer 2001;92:269; Cancer Res 2002;62:179], were evaluated in this ph
Autor:
Yasushi Ono, K. Matuda, Akihiko Gemma, Y. Takeda, Masahiro Seike, Akinobu Yoshimura, Masahiko Shibuya, Shouji Kudoh, Kazutsugu Uematsu, Yoko Hosoya, Kiyoshi Takenaka, Futoshi Kurimoto, Suguru Hibino
Publikováno v:
European Journal of Cancer. 37:1554-1561
Non-small cell lung cancer is associated with approximately 85% mortality due to its high metastatic potential. Therapeutic efforts have failed to produce a significant improvement in prognosis. In this situation, a better understanding of the key fa
Autor:
Akinobu Yoshimura, Yoko Hosoya, Shoji Kudoh, Futoshi Kurimoto, Suguru Hibino, Mitsuru Emi, Masahiro Seike, Masahiko Shibuya, Kazutsugu Uematsu, Akihiko Gemma
Publikováno v:
Lung Cancer. 32:289-295
Some of the many human cancers that exhibit chromosomal instability also carry mutations in mitotic checkpoint genes and/or reveal reduced expression of some of those genes, such as hMAD2. To facilitate investigation of alterations of hMAD2, we deter
Autor:
Masahiro Seike, Akihiko Gemma, Suguru Hibino, Akinobu Yoshimura, Curtis C. Harris, Masahiko Shibuya, Shoji Kudoh, Kazutsugu Uematsu, Yoko Seike, Futosi Kurimoto
Publikováno v:
Genes, Chromosomes and Cancer. 29:213-218
Mutations in mitotic checkpoint genes have been detected in several human cancers, and these cancers exhibit chromosomal instability. Aneuploid stem cells seem to result from chromosomal instability and have been reported in many lung cancers. To det
Autor:
Isao Goto, Shuichi Yoneda, Kazuhiro Kimura, Hiroshi Sakai, Toshiyuki Izumo, Hidetoshi Sumimoto, Fumikazu Takeda, Suguru Hibino, Yukio Noguchi, Mizuyoshi Sakura
Publikováno v:
Haigan. 36:879-883
当院で1977年以降経験した原発性肺癌1586例中癌性髄膜症を合併した22例について検討した.癌性髄膜症の合併率は1.4%で, 小細胞癌は10例/215例 (4.7%) と, 腺癌 (1.5%), 扁平上皮癌 (0.2%) に比べ有
Autor:
Kazuhiro Kimura, Suguru Hibino, Isao Goto, Hiroshi Sakai, Toshiyuki Izumo, Yukio Noguchi, Mizuyoshi Sakura, Syuichi Yoneda
Publikováno v:
Haigan. 35:407-415
肺癌脳転移の治療戦略を検討する目的で, 1977年以降経験した肺癌1586例中臨床的に診断した脳転移327例を対象に, 脳転移からの生存率を予後因子および治療因子別に単因子分析した. さら
Autor:
Sherilyn J. VanOsdol, Michael C. Wu, Rydhwana Hossain, Jean A. Engbring, Jennifer E. Koblinski, Benjamin Kaplan-Singer, Suguru Hibino
Publikováno v:
Clinicalexperimental metastasis. 25(3)
Laminin-111 promotes the malignant phenotype, and a 12-mer synthetic peptide (AG73, RKRLQVQLSIRT) from the carboxyl terminus of the alpha1 chain increases B16F10 melanoma metastasis to the lung and liver. Using an antibody array, fibronectin was iden
Autor:
Mari Iguchi, Tomohiro Ota, Masahiko Shibuya, Akihiko Gemma, Tatsuru Okamura, Kazuhiro Kitamura, Tsuneo Shimokawa, Suguru Hibino, Yukio Hosomi
Publikováno v:
International journal of clinical oncology. 14(1)
Amrubicin, a totally synthetic 9-aminoanthracycline, was evaluated retrospectively for the treatment of refractory and relapsed small-cell lung cancer (SCLC).Retrospective analysis was performed in 32 patients. Amrubicin was infused over 5 min on day
Autor:
Kiyoshi Koizumi, Hiroyuki Tajima, Shoji Kudoh, Jun Watari, Suguru Hibino, Yuji Okajima, Kazuo Yamamoto, Yuh Fukuda, Iwao Mikami, Hirotoshi Kubokura, Hiroshi Mochimaru, Akihiko Gemma, Akinobu Yoshimura, Tatsuo Kumazaki, Shinobu Henmi, Nobuaki Yamanaka, Kazutsugu Uematsu, Masahiro Andoh, Shigeo Tanaka
Publikováno v:
Journal of Nippon Medical School. 65:481-483