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Suppression of renal sympathetic nerve activity during portal vein infusion of hypertonic saline.

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Photo-Stability of Cianidanol in Aqueous Solution and in the Solid State.

Autor: Akimoto, Koichi, Nakagawa, Hiroshi, Sugimoto, Isao

Publikováno v: Drug Development & Industrial Pharmacy; 1985, Vol. 11 Issue 4, p865-889, 25p

Gas Chromatographic Determination of Degradation Products and Stability of Dehydroepiandrosterone Sulfate in Aqueous Solution.

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The stability of 1-cyclopropylmethyl-5(o-fluorophenyl)-7-chloro-1,3-dihydro-2H-1,4-benzodiazepin-2-one (KB-509) in aqueous solution

Autor: Sugimoto Isao, Awata Norio, Akimoto Koichi, Fujiwara Shigeru

Publikováno v: International Journal of Pharmaceutics. 3:109-115

The main degradation of 1-cyclopropylmethyl-5-(o-fluorophenyl)-7-chloro-l,3-dihydro-2H-1,4-benzodiazepin-2-one (KB-509) in aqueous solution involves a two-step consecutive mechanism. The first step is the hydrolysis of KB-509, yielding 5-chloro-cyclo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::9107055e2273b02a8d4e84527f4eb104
https://doi.org/10.1016/0378-5173(79)90072-3