The notch and TGF-β signaling pathways contribute to the aggressiveness of clear cell renal cell carcinoma.

Autor: Jonas Sjölund, Anna-Karin Boström, David Lindgren, Sugata Manna, Aristidis Moustakas, Börje Ljungberg, Martin Johansson, Erik Fredlund, Håkan Axelson

Publikováno v: PLoS ONE, Vol 6, Iss 8, p e23057 (2011)

BACKGROUND: Despite recent progress, therapy for metastatic clear cell renal cell carcinoma (CCRCC) is still inadequate. Dysregulated Notch signaling in CCRCC contributes to tumor growth, but the full spectrum of downstream processes regulated by Not

Externí odkaz: https://doaj.org/article/5e79b05ecc5e4f1f843e54b8383aee7c

Tea polyphenols can restrict benzo[a]pyrene-induced lung carcinogenesis by altered expression of p53-associated genes and H-ras, c-myc and cyclin D1

Autor: Sugata Manna, Sudeshna Mukherjee, Sukta Das, Anup Roy, Chinmay Kr. Panda

Publikováno v: The Journal of Nutritional Biochemistry. 20:337-349

The modulatory influence of tea polyphenols (epigallocatechin gallate, epicatechin gallate and theaflavin) on benzo[a]pyrene (B[a]P)-induced lung carcinogenesis in mice was analyzed using histopathological and molecular parameters. Progression of lun

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0d8947fd1a5c8fe1fe931be592d335a
https://doi.org/10.1016/j.jnutbio.2008.04.001

Intrathymic Injection

Autor: Sugata, Manna, Avinash, Bhandoola

Publikováno v: Methods in molecular biology (Clifton, N.J.). 1323

Intrathymic injection is used in several T cell-associated immunological studies to deliver cells or other substances directly into the thymus. Here, we describe the intrathymic injection procedure involving surgical incision of the mouse with or wit

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::1daf8421c8fdc1d3541c46c46b3ddcab
https://pubmed.ncbi.nlm.nih.gov/26294410

Histone H3 Lysine 27 demethylases Jmjd3 and Utx are required for T-cell differentiation

Autor: Bao Tran, Ehydel Castro, Jong Kyong Kim, Catherine Baugé, Rémy Bosselut, Sugata Manna, Jyoti Shetty, Margaret C. Cam, Lino Tessarollo, Melanie S. Vacchio, Yongmei Zhao

Publikováno v: Nature Communications
Nature Communications, Nature Publishing Group, 2014, 6, pp.8152. 〈10.1038/ncomms9152〉
Nature Communications, Nature Publishing Group, 2014, 6, pp.8152. ⟨10.1038/ncomms9152⟩

Although histone H3 lysine 27 trimethylation (H3K27Me3) is associated with gene silencing, whether H3K27Me3 demethylation affects transcription and cell differentiation in vivo has remained elusive. To investigate this, we conditionally inactivated t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::97dc145bf1c4341f35926d3ebb3fa57b
https://hal.archives-ouvertes.fr/hal-01249006

The Notch and TGF-beta Signaling Pathways Contribute to the Aggressiveness of Clear Cell Renal Cell Carcinoma

Autor: Jonas Sjölund, Martin Johansson, Börje Ljungberg, David Lindgren, Aristidis Moustakas, Sugata Manna, Håkan Axelson, Erik Fredlund, Anna-Karin Boström

Publikováno v: PLoS ONE; 6(8), no e23057 (2011)
PLoS ONE
PLoS ONE, Vol 6, Iss 8, p e23057 (2011)

BACKGROUND: Despite recent progress, therapy for metastatic clear cell renal cell carcinoma (CCRCC) is still inadequate. Dysregulated Notch signaling in CCRCC contributes to tumor growth, but the full spectrum of downstream processes regulated by Not

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd26d7da96ef37532c0d2c34cf210feb
https://lup.lub.lu.se/record/2151289