Selectivity issues in targeted metabolomics: Separation of phosphorylated carbohydrate isomers by mixed-mode hydrophilic interaction/weak anion exchange chromatography

Autor: Hinterwirth, Helmut, Lämmerhofer, Michael, Preinerstorfer, Beatrix, Gargano, Andrea, Reischl, Roland, Bicker, Wolfgang, Trapp, Oliver, Brecker, Lothar, Lindner, Wolfgang

Publikováno v: Hinterwirth, H, Lämmerhofer, M, Preinerstorfer, B, Gargano, A, Reischl, R, Bicker, W, Trapp, O, Brecker, L & Lindner, W 2010, Selectivity issues in targeted metabolomics: Separation of phosphorylated carbohydrate isomers by mixed-mode hydrophilic interaction/weak anion exchange chromatography . in Journal of Separation Science . Journal of Separation Science, vol. 33, pp. 3273-3282 . https://doi.org/10.1002/jssc.201000412
Journal of Separation Science, 3273-3282
STARTPAGE=3273;ENDPAGE=3282;TITLE=Journal of Separation Science

Phosphorylated carbohydrates are important intracellular metabolites and thus of prime interest in metabolomics research. Complications in their analysis arise from the existence of structural isomers that do have similar fragmentation patterns in MS

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::baf8a55dd1328977cf66394347d95dd1
https://doi.org/10.1002/jssc.201000412