DCZ0415, a small-molecule inhibitor targeting TRIP13, inhibits EMT and metastasis via inactivation of the FGFR4/STAT3 axis and the Wnt/β-catenin pathway in colorectal cancer.

Autor: Agarwal S; Department of Pathology, University of Alabama at Birmingham, AL, USA., Afaq F; Department of Pathology, University of Alabama at Birmingham, AL, USA., Bajpai P; Department of Pathology, University of Alabama at Birmingham, AL, USA., Kim HG; Department of Pathology, University of Alabama at Birmingham, AL, USA., Elkholy A; Department of Pathology, University of Alabama at Birmingham, AL, USA., Behring M; Department of Pathology, University of Alabama at Birmingham, AL, USA., Chandrashekar DS; Department of Pathology, University of Alabama at Birmingham, AL, USA., Diffalha SA; Department of Pathology, University of Alabama at Birmingham, AL, USA.; O'Neal Comprehensive Cancer Center, University of Alabama at Birmingham, AL, USA., Khushman M; O'Neal Comprehensive Cancer Center, University of Alabama at Birmingham, AL, USA.; Department of Medicine, Division of Medical Oncology, University of Alabama at Birmingham, AL, USA., Sugandha SP; Department of Medicine, Division of Gastroenterology, University of Alabama at Birmingham, AL, USA., Varambally S; Department of Pathology, University of Alabama at Birmingham, AL, USA.; O'Neal Comprehensive Cancer Center, University of Alabama at Birmingham, AL, USA., Manne U; Department of Pathology, University of Alabama at Birmingham, AL, USA.; O'Neal Comprehensive Cancer Center, University of Alabama at Birmingham, AL, USA.

Publikováno v: Molecular oncology [Mol Oncol] 2022 Apr; Vol. 16 (8), pp. 1728-1745. Date of Electronic Publication: 2022 Mar 07.

Prognostic value of loss of heterozygosity and sub-cellular localization of SMAD4 varies with tumor stage in colorectal cancer.

Autor: Jia X; Department of Pathology, University of Alabama at Birmingham, Birmingham, AL, USA., Shanmugam C; Department of Pathology, University of Alabama at Birmingham, Birmingham, AL, USA.; Current address: Department of Pathology, ESIC Medical College and Hospital, Sanathnagar, Hyderabad, Telangana, India., Paluri RK; Department of Medicine, University of Alabama at Birmingham, Birmingham, AL, USA., Jhala NC; Department of Pathology, University of Alabama at Birmingham, Birmingham, AL, USA.; Current address: Pathology & Laboratory Medicine, Temple University, Philadelphia, PA, USA., Behring MP; Department of Epidemiology, University of Alabama at Birmingham, Birmingham, AL, USA., Katkoori VR; Department of Pathology, University of Alabama at Birmingham, Birmingham, AL, USA.; Current address: Department of Surgery, Michigan State University, College of Human Medicine, Lansing, MI, USA., Sugandha SP; Department of Medicine, University of Alabama at Birmingham, Birmingham, AL, USA., Bae S; Department of Medicine, University of Alabama at Birmingham, Birmingham, AL, USA.; Comprehensive Cancer Center, University of Alabama at Birmingham, Birmingham, AL, USA., Samuel T; College of Veterinary Medicine, Tuskegee University, Tuskegee, AL, USA., Manne U; Department of Pathology, University of Alabama at Birmingham, Birmingham, AL, USA.; Comprehensive Cancer Center, University of Alabama at Birmingham, Birmingham, AL, USA.

Publikováno v: Oncotarget [Oncotarget] 2017 Mar 21; Vol. 8 (12), pp. 20198-20212.

Multicenter intestinal current measurements in rectal biopsies from CF and non-CF subjects to monitor CFTR function.

Autor: Clancy JP; Department of Pediatrics, Cincinnati Children's Hospital Medical Center and the University of Cincinnati, Cincinnati, Ohio, United States of America., Szczesniak RD, Ashlock MA, Ernst SE, Fan L, Hornick DB, Karp PH, Khan U, Lymp J, Ostmann AJ, Rezayat A, Starner TD, Sugandha SP, Sun H, Quinney N, Donaldson SH, Rowe SM, Gabriel SE

Publikováno v: PloS one [PLoS One] 2013 Sep 10; Vol. 8 (9), pp. e73905. Date of Electronic Publication: 2013 Sep 10 (Print Publication: 2013).

Roles and action mechanisms of NRIP1 in pre-eclampsia.

Autor: Gu F; Department of Obstetrics and Gynecology, Dalian Medical University, Dalian, 116000, China.; Department of Obstetrics and Gynecology, Northern Jiangsu People's Hospital, No. 98 Nantong West Road, Yangzhou, 225001, China., Zhang Y; Department of Obstetrics and Gynecology, Dalian Medical University, Dalian, 116000, China.; Department of Obstetrics and Gynecology, Northern Jiangsu People's Hospital, No. 98 Nantong West Road, Yangzhou, 225001, China., Sun Y; Department of Obstetrics and Gynecology, Dalian Medical University, Dalian, 116000, China., Liu Y; Department of Obstetrics and Gynecology, Northern Jiangsu People's Hospital, No. 98 Nantong West Road, Yangzhou, 225001, China., Zhang L; Department of Obstetrics and Gynecology, Northern Jiangsu People's Hospital, No. 98 Nantong West Road, Yangzhou, 225001, China., Lu D; Department of Obstetrics and Gynecology, Dalian Medical University, Dalian, 116000, China. ludan105913@163.com.; Department of Obstetrics and Gynecology, Northern Jiangsu People's Hospital, No. 98 Nantong West Road, Yangzhou, 225001, China. ludan105913@163.com.

Publikováno v: Genes & genomics [Genes Genomics] 2024 Sep 13. Date of Electronic Publication: 2024 Sep 13.

Targeting TRIP13 for overcoming anticancer drug resistance (Review).

Autor: Zhao, Liwen, Ye, Siyu, Jing, Shengnan, Gao, Yong-Jing, He, Tianzhen

Publikováno v: Oncology Reports; Nov2023, Vol. 50 Issue 5, pN.PAG-N.PAG, 1p