Zobrazeno 1 - 10
of 662
pro vyhledávání: '"Sug-Hyung Lee"'
Autor:
Jieying Liu, So Youn Kim, Sun Shin, Seung-Hyun Jung, Seon-Hee Yim, Ji Youl Lee, Sug-Hyung Lee, Yeun-Jun Chung
Publikováno v:
Experimental and Molecular Medicine, Vol 50, Iss 8, Pp 1-11 (2018)
Prostate cancer: Promising protein biomarker A protein found in high levels in prostate cancer tissues could provide a biomarker and therapeutic target for the disease. Prostate cancer (PCa) is a common cause of cancer-related death, yet existing bio
Externí odkaz:
https://doaj.org/article/9da45008b92947cda08d23cec0225d4a
Autor:
Jeesoo Chae, Seung-Hyun Jung, Eun Ji Choi, Jae Woong Kim, Na Yung Kim, Sung Won Moon, Ji Youl Lee, Yeun-Jun Chung, Sug Hyung Lee
Publikováno v:
Experimental and Molecular Medicine, Vol 56, Iss 1, Pp 168-176 (2024)
Abstract This study aimed to identify somatic mutations in nontumor cells (NSMs) in normal prostate and benign prostatic hyperplasia (BPH) and to determine their relatedness to prostate cancer (PCA). From 22 PCA patients, two prostates were sampled f
Externí odkaz:
https://doaj.org/article/e60bd6c7c40448188ca05528b0d67678
Autor:
Dokyeong Kim, Junseong Park, Hyeon-Chun Park, Songzi Zhang, Minyoung Park, Soon A. Park, Sug Hyung Lee, Youn Soo Lee, Jae-Sung Park, Sin-Soo Jeun, Yeun-Jun Chung, Stephen Ahn
Publikováno v:
Cancer Cell International, Vol 24, Iss 1, Pp 1-14 (2024)
Abstract Background Although meningioma is the most common primary brain tumor, treatments rely on surgery and radiotherapy, and recurrent meningiomas have no standard therapeutic options due to a lack of clinically relevant research models. Current
Externí odkaz:
https://doaj.org/article/eafc4d197aff4cbdbfe110702d502af7
Autor:
Junseong Park, Soon A. Park, Yoon-Seob Kim, Dokyeong Kim, Sun Shin, Sug Hyung Lee, Sin-Soo Jeun, Yeun-Jun Chung, Stephen Ahn
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 173, Iss , Pp 115790- (2024)
Background: Although PD-1 blockade is effective for treating several types of cancer, the efficacy of this agent in glioblastoma is largely limited. To overcome non-responders and the immunosuppressive tumor microenvironment, combinational immunother
Externí odkaz:
https://doaj.org/article/a83e706b6b684de4b58c23066ccffbf0
Publikováno v:
Journal of Pathology and Translational Medicine, Vol 57, Iss 1, Pp 43-51 (2023)
Traditionally, diagnostic pathology uses histology representing structural alterations in a disease’s cells and tissues. In many cases, however, it is supplemented by other morphology-based methods such as immunohistochemistry and fluorescent in si
Externí odkaz:
https://doaj.org/article/8568436fe1db421f9db8cbdf62e09fbf
Autor:
Nahyeon Kang, Su Yeon Choi, Bit Na Kim, Chang Dong Yeo, Chan Kwon Park, Young Kyoon Kim, Tae-Jung Kim, Seong-Beom Lee, Sug Hyung Lee, Jong Y. Park, Mi Sun Park, Hyeon Woo Yim, Seung Joon Kim
Publikováno v:
BMC Cancer, Vol 19, Iss 1, Pp 1-11 (2019)
Abstract Background A hypoxic microenvironment leads to an increase in the invasiveness and the metastatic potential of cancer cells within tumors via the epithelial-mesenchymal transition (EMT) and cancer stemness acquisition. However, hypoxia-induc
Externí odkaz:
https://doaj.org/article/9427da68453a4d5db0cb1f1d4ea2b0e5
Publikováno v:
Polish Journal of Pathology, Vol 68, Iss 3, Pp 258-260 (2017)
Both CUX1 and SIRT1 are considered tumor suppressor genes (TSGs), but it is not known whether CUX1 and SIRT1 alterations are different between high microsatellite instability (MSI-H) and microsatellite stable MSI (MSS) cancers. We identified frameshi
Externí odkaz:
https://doaj.org/article/3372ba94d0dc412fa43c2f53caebbb22
Autor:
Sug Hyung Lee, Yeun-Jun Chung, Min Sung Kim, Hyeon-Chun Park, Eun Sun Jung, Sung Hak Lee, Chang Hyeok An, Shin Young Kim, Seung-Hyun Jung
Purpose: Gastric adenoma (GA) is a premalignant lesion that precedes intestinal-type gastric carcinoma (GC). However, genetic progression mechanisms from GA to GC have not been clarified.Experimental Design: We performed whole-exome sequencing–base
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5580e53505f54c42c340620f546525d6
https://doi.org/10.1158/1078-0432.c.6527205.v1
https://doi.org/10.1158/1078-0432.c.6527205.v1
Autor:
Kyung Keun Kim, Hangun Kim, Sug Hyung Lee, Ik Joo Chung, Young Eun Joo, Jae Hyuk Lee, Kyu Youn Ahn, Kyung Hwa Lee, Somy Yoon, Yoo-Seung Ko, Eun Gene Sun, Dhong Hyo Kho, Jeong A Bae
Supplementary Figure legends; Supplementary Materials and Methods: Detailed and expanded methods on cell lines, in-vitro assays, in-vivo tumor model, histology, and tumor specimens for all data presented.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2bbd0e44fdffa395520a5c3686784ef5
https://doi.org/10.1158/1078-0432.22457565.v1
https://doi.org/10.1158/1078-0432.22457565.v1
Autor:
Kyung Keun Kim, Hangun Kim, Sug Hyung Lee, Ik Joo Chung, Young Eun Joo, Jae Hyuk Lee, Kyu Youn Ahn, Kyung Hwa Lee, Somy Yoon, Yoo-Seung Ko, Eun Gene Sun, Dhong Hyo Kho, Jeong A Bae
Generation and characterization of villin-KITENIN/APCmin/+ mice.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::169a73cfe298701ad9f9d066c48cf9cd
https://doi.org/10.1158/1078-0432.22457580.v1
https://doi.org/10.1158/1078-0432.22457580.v1