The Anti-Tumor Effects of Adipose Tissue Mesenchymal Stem Cell Transduced with HSV-Tk Gene on U-87-Driven Brain Tumor.

Autor: Suely Maymone de Melo, Simone Bittencourt, Enéas Galdini Ferrazoli, Clivandir Severino da Silva, Flavia Franco da Cunha, Flavia Helena da Silva, Roberta Sessa Stilhano, Priscila Martins Andrade Denapoli, Bianca Ferrarini Zanetti, Priscila Keiko Matsumoto Martin, Leonardo Martins Silva, Adara Aurea dos Santos, Leandra Santos Baptista, Beatriz Monteiro Longo, Sang Won Han

Publikováno v: PLoS ONE, Vol 10, Iss 6, p e0128922 (2015)

Glioblastoma (GBM) is an infiltrative tumor that is difficult to eradicate. Treating GBM with mesenchymal stem cells (MSCs) that have been modified with the HSV-Tk suicide gene has brought significant advances mainly because MSCs are chemoattracted t

Externí odkaz: https://doaj.org/article/54b309cd0471482b88deb1e3bd04804a

Hypofractionated radiotherapy for newly diagnosed elderly glioblastoma patients: A systematic review and network meta-analysis

Autor: Carolina de Oliveira Cruz Latorraca, Rachel Riera, Gustavo Nader Marta, Orestis Efthimiou, Camila Bertini Martins, Suely Maymone de Melo

Publikováno v: Melo, Suely Maymone de; Marta, Gustavo Nader; Latorraca, Carolina de Oliveira Cruz; Martins, Camila Bertini; Efthimiou, Orestis; Riera, Rachel (2021). Hypofractionated radiotherapy for newly diagnosed elderly glioblastoma patients: A systematic review and network meta-analysis. PLoS ONE, 16(11), e0257384. Public Library of Science 10.1371/journal.pone.0257384
PLoS ONE, Vol 16, Iss 11, p e0257384 (2021)
PLoS ONE
PLoS ONE, Vol 16, Iss 11 (2021)

Objective To evaluate different hypofractionated radiotherapy (HRT) regimens for newly diagnosed elderly glioblastoma (GBM) patients. Methods We performed a systematic review with network meta-analysis (NMA), including searches on CENTRAL, Medline, E

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d075b01df8a0b8c6fda1adac2c0021b
https://boris.unibe.ch/160852/1/Melo_PLoSOne_2021.pdf

α-l-iduronidase gene-based therapy using the phiC31 system to treat mucopolysaccharidose type I mice

Autor: Yara M. Michelacci, Suely Maymone de Melo, Vivian Yochiko Samoto, Flávia Helena da Silva, Adriana Taveira da Cruz, Vania D'Almeida, Vanessa Gonçalves Pereira, Sang Won Han, Roberta Sessa Stilhano, Miriam Galvonas Jasiulionis, Priscila Keiko Matsumoto Martin, Giovani B. Peres

Publikováno v: The Journal of Gene Medicine. 17:1-13

Background Mucopolysaccharidose type I (MPSI) is a lysosomal monogenic disease caused by mutations in the gene for α- l-iduronidase (IDUA). MPSI patients need a constant supply of IDUA to alleviate progression of the disease. IDUA gene transfer usin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::694e8d93626369410ed73f82844a4b96
https://doi.org/10.1002/jgm.2818

The Anti-Tumor Effects of Adipose Tissue Mesenchymal Stem Cell Transduced with HSV-Tk Gene on U-87-Driven Brain Tumor

Autor: Beatriz M. Longo, Clivandir Severino da Silva, Simone Bittencourt, Roberta Sessa Stilhano, Sang Won Han, Priscila Keiko Matsumoto Martin, Bianca Ferrarini Zanetti, Priscila Martins Andrade Denapoli, Flávia Helena da Silva, Adara Aurea dos Santos, Leandra Santos Baptista, Suely Maymone de Melo, Enéas Galdini Ferrazoli, Flavia Franco da Cunha, Leonardo Martins Silva

Publikováno v: PLoS ONE, Vol 10, Iss 6, p e0128922 (2015)
PLoS ONE

Glioblastoma (GBM) is an infiltrative tumor that is difficult to eradicate. Treating GBM with mesenchymal stem cells (MSCs) that have been modified with the HSV-Tk suicide gene has brought significant advances mainly because MSCs are chemoattracted t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3bb6b003ac3fcf02111935721b3222d
http://europepmc.org/articles/PMC4467037?pdf=render

636. The Anti-Tumor Effects of Adipose Tissue Mesenchymal Stem Cell Transduced With HSV-1-TK Gene on U87-Driven Brain Tumor

Autor: Adara Aurea dos Santos, Roberta Sessa Stilhano, Leandra Santos Baptista, Priscila Martins Andrade Denapoli, Leonardo Martins Silva, Enéas Galdini Ferrazoli, Beatriz M. Longo, Simone Bittencourt, Suely Maymone de Melo, Sang Won Han, Pricila K. Martins, Clivandir Severino da Silva, Bianca Ferrarini Zanetti, Flavia Franco da Cunha

Publikováno v: Molecular Therapy. 23:S253

Glioblastoma (GBM) is the most common and lethal primary intracranial tumor. Because GBM is highly invasive and diffusely infiltrates the brain, a complete resection of the tumor is unfeasible. The gene encoding thymidine kinase from herpes simplex v

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8ab7a1c096207f00cb42c9a4d74dd72
https://doi.org/10.1016/s1525-0016(16)34245-9