Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Suellen Pinheiro Carvalho"'
Autor:
Sètondji Cocou Modeste Alexandre Yahouédéhou, Joelma Santana dos Santos Neres, Caroline Conceição da Guarda, Suellen Pinheiro Carvalho, Rayra Pereira Santiago, Camylla Vilas Boas Figueiredo, Luciana Magalhães Fiuza, Uche Samuel Ndidi, Rodrigo Mota de Oliveira, Cleverson Alves Fonseca, Valma Maria Lopes Nascimento, Larissa Carneiro Rocha, Corynne Stéphanie Ahouéfa Adanho, Tiago Santos Carvalho da Rocha, Elisângela Vitória Adorno, Marilda Souza Goncalves
Publikováno v:
Frontiers in Pharmacology, Vol 11 (2020)
Differences in hydroxyurea response in sickle cell anemia may arise due to a series of factors with genetic factors appearing to be predominant. This study aims to investigate the effects of single nucleotide polymorphisms in genes encoding drug-meta
Externí odkaz:
https://doaj.org/article/3400dd841545442395b4388443304024
Autor:
Caroline Conceição da Guarda, Sètondji Cocou Modeste Alexandre Yahouédéhou, Rayra Pereira Santiago, Joelma Santana Dos Santos Neres, Camila Felix de Lima Fernandes, Milena Magalhães Aleluia, Camylla Vilas Boas Figueiredo, Luciana Magalhães Fiuza, Suellen Pinheiro Carvalho, Rodrigo Mota de Oliveira, Cleverson Alves Fonseca, Uche Samuel Ndidi, Valma Maria Lopes Nascimento, Larissa Carneiro Rocha, Marilda Souza Goncalves
Publikováno v:
PLoS ONE, Vol 15, Iss 1, p e0228399 (2020)
Sickle cell disease (SCD) consists of a group of hemoglobinopathies in which individuals present highly variable clinical manifestations. Sickle cell anemia (SCA) is the most severe form, while SC hemoglobinopathy (HbSC) is thought to be milder. Thus
Externí odkaz:
https://doaj.org/article/f8190f50a51a4031937210902d2562a8
Autor:
Sètondji Cocou Modeste Alexandre Yahouédéhou, Caroline Conceição da Guarda, Camylla Vilas Boas Figueiredo, Rayra Pereira Santiago, Suellen Pinheiro Carvalho, Luciana Magalhães Fiuza, Uche Samuel Ndidi, Rodrigo Mota Oliveira, Magda Oliveira Seixas Carvalho, Valma Maria Lopes Nascimento, Larissa Carneiro Rocha, Isa Menezes Lyra, Elisângela Vitória Adorno, Marilda Souza Goncalves
Publikováno v:
PLoS ONE, Vol 14, Iss 7, p e0218040 (2019)
This study investigated the effects of hydroxyurea (HU) on hematological, biochemical and inflammatory parameters in children with sickle cell anemia (SCA) in association with βS haplotype and α-thalassemia. We included 22 children with SCA who wer
Externí odkaz:
https://doaj.org/article/75c771f077224792836bb5f6109ca140
Autor:
Rayra Pereira Santiago, Sètondji Cocou Modeste Alexandre Yahouédéhou, Valma Maria Lopes Nascimento, Marilda Souza Goncalves, Rodrigo Mota de Oliveira, Cleverson Alves Fonseca, Caroline Conceição da Guarda, Camylla V. B. Figueiredo, Larissa Carneiro Rocha, Suellen Pinheiro Carvalho, Milena Magalhães Aleluia, Luciana Magalhães Fiuza
Publikováno v:
Mediators of Inflammation
Mediators of Inflammation, Vol 2020 (2020)
Mediators of Inflammation, Vol 2020 (2020)
Individuals with sickle cell disease (SCD) present both chronic and acute inflammatory events. The TGF-β pathway is known to play a role in immune response, angiogenesis, inflammation, hematopoiesis, vascular inflammation, and cell proliferation. Po
Autor:
Rayra Pereira Santiago, Rodrigo Mota de Oliveira, Cleverson Alves Fonseca, Milena Magalhães Aleluia, Camylla Vilas Boas Figueiredo, Larissa Carneiro Rocha, Marilda Souza Goncalves, Caroline Conceição da Guarda, Joelma Santana dos Santos Neres, Valma Maria Lopes Nascimento, Suellen Pinheiro Carvalho, Luciana Magalhães Fiuza, Sètondji Cocou Modeste Alexandre Yahouédéhou, Antonio Mateus de Jesus Oliveira, Camila Felix de Lima Fernandes
Publikováno v:
Disease Markers, Vol 2020 (2020)
Disease Markers
Disease Markers
Introduction. Clinical complications in sickle cell anemia (SCA) are heterogeneous and involve several molecules. It has been suggested that SCA individuals present a dyslipidemic phenotype and that lipid parameters are associated with severe clinica
Autor:
Valma Maria Lopes Nascimento, Luciana Magalhães Fiuza, Isa Menezes Lyra, Antonio Mateus de Jesus Oliveira, Camylla Vilas Boas Figueiredo, Rodrigo Mota de Oliveira, Rayra Pereira Santiago, Cleverson Alves Fonseca, Caroline Conceição da Guarda, Suellen Pinheiro Carvalho, Sètondji Cocou Modeste Alexandre Yahouédéhou, Milena Magalhães Aleluia, Joelma Santana dos Santos Neres, Marilda Souza Goncalves
Publikováno v:
PLoS ONE, Vol 16, Iss 2, p e0246067 (2021)
PLoS ONE
PLoS ONE
Priapism is a urologic emergency characterized by an uncontrolled, persistent and painful erection in the absence of sexual stimulation, which can lead to penile fibrosis and impotence. It is highly frequent in sickle cell disease (SCD) associated wi
Autor:
Valma Maria Lopes Nascimento, Luciana Magalhães Fiuza, Rayra Pereira Santiago, Larissa Carneiro Rocha, Camila Felix de Lima Fernandes, Rodrigo Mota de Oliveira, Uche Samuel Ndidi, Marilda Souza Goncalves, Cleverson Alves Fonseca, Camylla Vilas Boas Figueiredo, Sètondji Cocou Modeste Alexandre Yahouédéhou, Caroline Conceição da Guarda, Milena Magalhães Aleluia, Joelma Santana dos Santos Neres, Suellen Pinheiro Carvalho
Publikováno v:
PLoS ONE, Vol 15, Iss 1, p e0228399 (2020)
PLoS ONE
PLoS ONE
Sickle cell disease (SCD) consists of a group of hemoglobinopathies in which individuals present highly variable clinical manifestations. Sickle cell anemia (SCA) is the most severe form, while SC hemoglobinopathy (HbSC) is thought to be milder. Thus
Autor:
Milena Magalhães Aleluia, Elisângela Vitória Adorno, Rodrigo Mota de Oliveira, Caroline Conceição da Guarda, Uche Samuel Ndidi, Marilda Souza Goncalves, Suellen Pinheiro Carvalho, Sètondji Cocou Modeste Alexandre Yahouédéhou, Rayra Pereira Santiago
Publikováno v:
The Pharmacogenomics Journal. 18:730-739
Hydroxyurea (HU) was approved to be used in the treatment of sickle cell disease (SCD) because of its anti-sickling potential. However, there is variability in HU response among SCD patients and this can be due to physiological, socioeconomic, enviro
Autor:
Marilda Souza Goncalves, Caroline Conceição da Guarda, Sètondji Cocou Modeste Alexandre Yahouédéhou, Elisângela Vitória Adorno, Rayra Pereira Santiago, Rodrigo Mota de Oliveira, Suellen Pinheiro Carvalho, Milena Magalhães Aleluia, Júnia Raquel Dutra Ferreira, Magda Oliveira Seixas Carvalho
Publikováno v:
Disease Markers
Disease Markers, Vol 2018 (2018)
Disease Markers, Vol 2018 (2018)
This study investigated associations between SNPs in genes encoding metabolizing drug enzymes and laboratory parameters in sickle cell anemia patients under hydroxyurea (SCA-HU+). We evaluated hematologic and biochemical parameters by electronic meth
Autor:
Sètondji Cocou Modeste Alexandre Yahouédéhou, Marilda Souza Goncalves, Luciana Magalhães Fiuza, Valma Maria Lopes Nascimento, Milena Magalhães Aleluia, Camylla V. B. Figueiredo, Rodrigo Mota de Oliveira, Caroline Conceição da Guarda, Paulo S. Silveira-Mattos, Rayra Pereira Santiago, Valéria M. Borges, Suellen Pinheiro Carvalho, Bruno B. Andrade, Nívea F. Luz
Publikováno v:
Scientific Reports
Scientific Reports, Vol 9, Iss 1, Pp 1-11 (2019)
Scientific Reports, Vol 9, Iss 1, Pp 1-11 (2019)
Sickle cell anemia (SCA) is a hemolytic disease in which vaso-occlusion is an important pathophysiological mechanism. The treatment is based on hydroxyurea (HU), which decreases leukocyte counts and increases fetal hemoglobin synthesis. Different cel