Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Sue Stephens"'
Publikováno v:
Antibody Therapeutics ISBN: 9780429260360
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c55aa4ecb8a0e4bb0eb1df61bbd152b7
https://doi.org/10.1201/9780429260360-18
https://doi.org/10.1201/9780429260360-18
Autor:
Shawna V. Hudson, Sue Stephens, Jerod L. Stapleton, Margaret Masterson, Katie A. Devine, Kristina L. Tatum, Elliot J. Coups, Amna Baig
Publikováno v:
Pediatric Blood & Cancer. 63:554-557
The risk of developing skin cancer is elevated among childhood cancer survivors (CCS), particularly among those treated with radiation. This survey study examined the skin cancer surveillance behaviors of 94 CCS. Approximately 48% of CCS had ever con
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4e60a2d9427c9cbdd8428771a6ef4c99
https://doi.org/10.1002/pbc.25811
https://doi.org/10.1002/pbc.25811
Autor:
Stephen R. Indelicato, Nicholas J Murgoloa, Aileen Schilling, Steven H Weiner, Susan Sehring, Richard W. Chapman, Chung-Her Jenha, Xiomara Fernandez, Diljeet Athwal, Spencer J Emtage, Mary Ann Coxa, Sue Stephens, Mark W. Bodmer, Jacqueline M Carter, Dawn Stelts, Chuan-Chu Choua, J. A. Zurcher, William Kreutner, Ted T Kunga, Michael Minnicozzi, Nancy Genatt, Satwant K. Narula, Peter J. Mauser, Robert W. Egan, S. Shane Taremi, Paul J. Zavodny, Petro Mary E
Publikováno v:
Arzneimittelforschung. 49:779-790
This report describes the development and the biology of Sch 55700, a humanized monoclonal antibody to human IL-5 (hIL-5). Sch 55700 was synthesized using CDR (complementarity determining regions) grafting technology by incorporating the antigen reco
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ecd5539c9bec5537f2d898f89b07ce1
https://doi.org/10.1055/s-0031-1300502
https://doi.org/10.1055/s-0031-1300502
Autor:
Niti Goel, Sue Stephens
Publikováno v:
mAbs. 2:137-147
Certolizumab pegol (Cimzia(®)) is currently the only PEGylated anti-TNFα biologic approved for the treatment of rheumatoid arthritis and Crohn disease. The product, developed by UCB, is a humanized antigen-binding fragment (Fab') of a monoclonal an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08ef0d6b28b5eb1530e6caad5f10ba23
https://doi.org/10.4161/mabs.2.2.11271
https://doi.org/10.4161/mabs.2.2.11271
Autor:
Neil Weir, Dee Athwal, Derek Brown, Roly Foulkes, George Kollias, Andrew Nesbitt, Andy Popplewell, Mari Spitali, Sue Stephens
Publikováno v:
Therapy. 3:535-545
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fb817a99ca234d467a2f13e80ab3f9cf
https://doi.org/10.1586/14750708.3.4.535
https://doi.org/10.1586/14750708.3.4.535
Autor:
Neil Weir, Andrew Nesbitt, Sue Stephens, Mari Spitali, Dee Athwal, George Kollias, Derek Thomas Brown, Andy Popplewell, Roly Foulkes
Publikováno v:
Therapy. 3:535-545
Advances in immunotherapy through the development of chimeric, humanized and fully human monoclonal antibodies have improved treatment and reduced immunogenicity. These strategies produced biological anti-tumor necrosis factor-α therapies for inflam
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d47809cf107b28d692415d403db0b9cf
https://doi.org/10.2217/14750708.3.4.535
https://doi.org/10.2217/14750708.3.4.535
Autor:
Latha Sridharan, Sue Stephens, Douglas Armellino, Nitin K. Damle, Justin Keith Moran, Hamann Philip Ross, Kiran Khandke, Chandrasekhar Udata, Andrew George Popplewell, Philip Frost, John F. DiJoseph, Maureen Dougher, Boris Gorovits, Arthur Kunz, Erwin R. Boghaert
Publikováno v:
Blood. 103:1807-1814
Antibody-targeted chemotherapy with gemtuzumab ozogamicin (CMA-676, a CD33-targeted immunoconjugate of N-acetyl-γ-calicheamicin dimethyl hydrazide [CalichDMH], a potent DNA-binding cytotoxic antitumor antibiotic) is a clinically validated therapeuti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::157eef4aa22cae02adaa22ecfa024dd3
https://doi.org/10.1182/blood-2003-07-2466
https://doi.org/10.1182/blood-2003-07-2466
Autor:
Ursula M. Ney, Christian Richard, Claude Martin, Sue Stephens, Jean Louis Vincent, Jean-François Dhainaut, Lisiane Fierobe, Philippe Lejeune, Mark Sopwith
Publikováno v:
Critical Care Medicine. 23:1461-1469
Objectives To determine the safety of a ``humanized'' antibody to human anti-tumor necrosis factor-alpha (TNF-alpha) in patients with septic shock, and to examine the pharmacokinetics, immune response, and influence of the antibody on cytokine concen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a1b4524d64f687fbcdb940c6b8dc157a
https://doi.org/10.1097/00003246-199509000-00004
https://doi.org/10.1097/00003246-199509000-00004
Autor:
A J Suitters, R Foulkes, A R Holt, J S Emtage, Sue Stephens, John E. Palardy, M Rolfe, L Chaplin, Steven M. Opal, A Morgan
Publikováno v:
The Journal of Experimental Medicine
Immune complexes containing human gamma (g)1 or murine g2a antibodies generate secondary effector mechanisms via Fc receptor binding or complement activation, whereas those containing human g4 or murine g1 antibodies generally do not. Therefore, isot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38d8d1a943daff961961927f5e2ea3f2
https://doi.org/10.1084/jem.179.3.849
https://doi.org/10.1084/jem.179.3.849
Autor:
CHARLES J. FISHER, STEVEN M. OPAL, JEAN-FRANÇOIS DHAINAUT, SUE STEPHENS, JANICE L. ZIMMERMAN, PETER NIGHTINGALE, SIMON J. HARRIS, ROLAND M. H. SCHEIN, EDWARD A. PANACEK, JEAN-LOUIS VINCENT, GARRETT E. FOULKE, EDWARD L. WARREN, CHRIS GARRARD, GILBERT PARK, MARK W. BODMER, JONATHAN COHEN, CEES VAN DER LINDEN, ALAN S. CROSS, JERALD C. SADOFF
Publikováno v:
Critical Care Medicine. 21:318-327
OBJECTIVES To determine the safety, pharmacokinetics, and activity of an anti-tumor necrosis factor (TNF)-alpha monoclonal antibody in severe sepsis. DESIGN Open-label, prospective, phase II multicenter trial with escalating doses of a murine monoclo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e12942d6c14fd292af3d4ed409079ffc
https://doi.org/10.1097/00003246-199303000-00006
https://doi.org/10.1097/00003246-199303000-00006