Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Sue Penrhyn-Lowe"'
Autor:
Phaedra M Tachtatzis, Aileen Marshall, Aloysious Arvinthan, Suman Verma, Sue Penrhyn-Lowe, Marianna Mela, Cinzia Scarpini, Susan E Davies, Nicholas Coleman, Graeme J M Alexander
Publikováno v:
PLoS ONE, Vol 10, Iss 5, p e0127511 (2015)
BackgroundChronic Hepatitis B virus (HBV) infection can lead to the development of chronic hepatitis, cirrhosis and hepatocellular carcinoma. We hypothesized that HBV might accelerate hepatocyte ageing and investigated the effect of HBV on hepatocyte
Externí odkaz:
https://doaj.org/article/890fd41d4e1e47a9a387e1ab2f3df2ad
Autor:
Phaedra M Tachtatzis, Aileen Marshall, Aloysious Aravinthan, Suman Verma, Sue Penrhyn-Lowe, Marianna Mela, Cinzia Scarpini, Susan E Davies, Nicholas Coleman, Graeme J M Alexander
Publikováno v:
PLoS ONE, Vol 10, Iss 7, p e0134315 (2015)
Externí odkaz:
https://doaj.org/article/b3009ddeb526402fa50d077775c956da
Autor:
S. Verma, Aileen Marshall, Aloysious Aravinthan, Nicholas Coleman, Marianna Mela, Susan E. Davies, Cinzia G. Scarpini, P. Tachtatzis, Sue Penrhyn-Lowe, Graeme J.M. Alexander
Publikováno v:
PLoS ONE, Vol 10, Iss 5, p e0127511 (2015)
PLoS ONE
PLoS ONE
BackgroundChronic Hepatitis B virus (HBV) infection can lead to the development of chronic hepatitis, cirrhosis and hepatocellular carcinoma. We hypothesized that HBV might accelerate hepatocyte ageing and investigated the effect of HBV on hepatocyte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::effa9a45eae1b3f1f8a3218026594bf5
Autor:
Aloysious Aravinthan, Michael Allison, S. Verma, Cinzia G. Scarpini, Susan E. Davies, Rebecca Harvey, Graeme J.M. Alexander, Sue Penrhyn-Lowe, Nicholas Coleman, P. Tachtatzis
Publikováno v:
Journal of Hepatology. 58:549-556
Background & Aims Models of non-alcohol-related fatty liver disease (NAFLD) reveal features of accelerated ageing, such as impaired regeneration, and an increased risk of hepatocellular carcinoma. The relation between accelerated ageing, disease prog
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ed2833c6e732e169bbf3fd40cf02640a
https://doi.org/10.1016/j.jhep.2012.10.031
https://doi.org/10.1016/j.jhep.2012.10.031
Autor:
Thomas von Zglinicki, Diana Jurk, Cinzia G. Scarpini, S. Verma, Sue Penrhyn-Lowe, Graeme J.M. Alexander, Phaedra M. Tachtatzis, Nicholas Coleman
Publikováno v:
Hepatology. 56:1510-1520
Telomeres, a validated biomarker of aging, comprise multiple nucleotide repeats capping chromosomes that shorten with each cell cycle until a critical length is achieved, precipitating cell senescence. Only two previous studies focused on the effect
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fcb94b32f8f8b172e7bbaa49a9734462
https://doi.org/10.1002/hep.25787
https://doi.org/10.1002/hep.25787
Autor:
Sue Penrhyn-Lowe, Anthony D. Mills, Jackie Marr, Murray Stewart, Paul I.A. McMurtrie, Vihandha O. Wickramasinghe, Yoshinori Takei, Yoko Amagase, Sarah Main, Ronald A. Laskey
Publikováno v:
Current Biology
Summary Bulk nuclear export of messenger ribonucleoproteins (mRNPs) through nuclear pore complexes (NPCs) is mediated by NXF1. It binds mRNPs through adaptor proteins such as ALY [1, 2] and SR splicing factors [3] and mediates translocation through t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0739652fcfe4bffa0aa7547d767db36
http://europepmc.org/articles/PMC2869303
http://europepmc.org/articles/PMC2869303
Autor:
Cinzia G. Scarpini, Phaedra M. Tachtatzis, Sue Penrhyn-Lowe, S. Verma, Aloysious Aravinthan, Susan E. Davies, Nicholas Coleman, Richard D. Parker, Graeme J.M. Alexander
Publikováno v:
Gastroenterology. 140:S-899
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dbe4bb21d4df5477c22dfcab4ec109cc
https://doi.org/10.1016/s0016-5085(11)63732-3
https://doi.org/10.1016/s0016-5085(11)63732-3
Autor:
Phaedra M. Tachtatzis, Aloysious Aravinthan, Nicholas Coleman, Cinzia G. Scarpini, Michael Allison, Susan E. Davies, Rebecca Brais, S. Verma, Sue Penrhyn-Lowe, Graeme J.M. Alexander
Publikováno v:
Gastroenterology. 140:S-983
were fed a standard diet (SD). Blood and tissue samples were used for histological, biochemical and molecular analyses. HepG2 cells were used as a model to study molecular pathways that control LITAF expression/activity. Results: We found that either
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::61306463a5a1ee558c73cbc4b4ae55bc
https://doi.org/10.1016/s0016-5085(11)64076-6
https://doi.org/10.1016/s0016-5085(11)64076-6
Autor:
Aloysious Aravinthan, Phaedra M. Tachtatzis, Cinzia G. Scarpini, Sue Penrhyn-Lowe, Graeme J.M. Alexander, Nicholas Coleman, Michael Allison
Publikováno v:
Gastroenterology. 140:S-977
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::452f56163e18268a2bb9b8e0532be338
https://doi.org/10.1016/s0016-5085(11)64045-6
https://doi.org/10.1016/s0016-5085(11)64045-6
Autor:
GraemeJ.M. Alexander, Richard Parker, Nicholas Coleman, P. Tachtatzis, Cinzia G. Scarpini, Sumita Verma, Aloysious Aravinthan, Susan E. Davies, Sue Penrhyn-Lowe
Publikováno v:
Journal of Hepatology. 54:S445
Serologic markers did not change during a one to 38 months followup (median: 7). HBV-DNA enrichment improved virus detection, increasing HBV identification from 57% to 81% in enriched samples by the commercial RT assay and in all samples by the home-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8360dcf3603075aba1dc52ab686e5443
https://doi.org/10.1016/s0168-8278(11)61126-4
https://doi.org/10.1016/s0168-8278(11)61126-4