Zobrazeno 1 - 10
of 108
pro vyhledávání: '"Sue L. Jaspersen"'
Autor:
Joseph M. Varberg, Jennifer M. Gardner, Scott McCroskey, Snehabala Saravanan, William D. Bradford, Sue L. Jaspersen
Publikováno v:
G3: Genes, Genomes, Genetics, Vol 10, Iss 12, Pp 4649-4663 (2020)
The nuclear envelope (NE) contains a specialized set of integral membrane proteins that maintain nuclear shape and integrity and influence chromatin organization and gene expression. Advances in proteomics techniques and studies in model organisms ha
Externí odkaz:
https://doaj.org/article/39d8320235964823add2392c2be4146b
Publikováno v:
G3: Genes, Genomes, Genetics, Vol 11, Iss 12 (2021)
AbstractThe inner nuclear membrane (INM) proteome regulates gene expression, chromatin organization, and nuclear transport; however, it is poorly understood how changes in INM protein composition contribute to developmentally regulated processes, suc
Externí odkaz:
https://doaj.org/article/a329138cd5844a7fb73b01602376180a
Autor:
Jingjing Chen, Zhiyong Xiong, Danny E Miller, Zulin Yu, Scott McCroskey, William D Bradford, Ann M Cavanaugh, Sue L Jaspersen
Publikováno v:
PLoS Genetics, Vol 16, Iss 12, p e1008911 (2020)
Ploidy is the number of whole sets of chromosomes in a species. Ploidy is typically a stable cellular feature that is critical for survival. Polyploidization is a route recognized to increase gene dosage, improve fitness under stressful conditions an
Externí odkaz:
https://doaj.org/article/99ad4993dd1d45c7b9c463221fb73148
Autor:
Sara González-Arranz, Jennifer M. Gardner, Zulin Yu, Neem J. Patel, Jonna Heldrich, Beatriz Santos, Jesús A. Carballo, Sue L. Jaspersen, Andreas Hochwagen, Pedro A. San-Segundo
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 8 (2020)
The H2A.Z histone variant is deposited into the chromatin by the SWR1 complex, affecting multiple aspects of meiosis. We describe here a SWR1-independent localization of H2A.Z at meiotic telomeres and the centrosome. We demonstrate that H2A.Z colocal
Externí odkaz:
https://doaj.org/article/944e9d60a2444eba987785113b395d80
Autor:
Marco Geymonat, Qiuran Peng, Zhiang Guo, Zulin Yu, Jay R Unruh, Sue L Jaspersen, Marisa Segal
Publikováno v:
eLife, Vol 9 (2020)
Asymmetric astral microtubule organization drives the polarized orientation of the S. cerevisiae mitotic spindle and primes the invariant inheritance of the old spindle pole body (SPB, the yeast centrosome) by the bud. This model has anticipated anal
Externí odkaz:
https://doaj.org/article/8aeab2261ead469682d26e8b35cfa745
Autor:
Sue L. Jaspersen, Deborah A. Bruns, Meghan S. Candee, Agatino Battaglia, John C. Carey, Kristen P. Fishler
Publikováno v:
American journal of medical genetics. Part AREFERENCES.
Changes in medical intervention over the last decade have improved outcomes for individuals with trisomy 18, the second most common human aneuploidy syndrome at birth. As children with trisomy 18 live longer, a shared concern of medical experts and p
Publikováno v:
Molecular Biology of the Cell
Proper mitotic progression inSchizosaccharomyces pomberequires partial nuclear envelope breakdown (NEBD) and insertion of the spindle pole body (SPB – yeast centrosome) to build the mitotic spindle. Linkage of the centromere to the SPB is vital to
Autor:
Nicole L Nuckolls, María Angélica Bravo Núñez, Michael T Eickbush, Janet M Young, Jeffrey J Lange, Jonathan S Yu, Gerald R Smith, Sue L Jaspersen, Harmit S Malik, Sarah E Zanders
Publikováno v:
eLife, Vol 6 (2017)
Meiotic drivers are selfish genes that bias their transmission into gametes, defying Mendelian inheritance. Despite the significant impact of these genomic parasites on evolution and infertility, few meiotic drive loci have been identified or mechani
Externí odkaz:
https://doaj.org/article/8bcb5e63312e483a9de36a4bcdd724ad
Autor:
Joseph M. Varberg, Sue L. Jaspersen
Publikováno v:
Cell Reports, Vol 23, Iss 4, Pp 931-932 (2018)
In fission yeast, the nuclear envelope (NE) remains intact during mitosis and meiosis I but is compromised during meiosis II. In this issue of Cell Reports, Flor-Parra et al. (2018) demonstrate that this NE alteration regulates meiosis II spindle dis
Externí odkaz:
https://doaj.org/article/13162f366d2a45f2aacda6cec7c66a99
Autor:
Sue L. Jaspersen
Publikováno v:
Curr Opin Struct Biol
The fungal kingdom is large and diverse, representing extremes of ecology, life cycles and morphology. At a cellular level, the diversity among fungi is particularly apparent at the spindle pole body (SPB). This nuclear envelope embedded structure, w