Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Sue L. Cousart"'
Autor:
Xiaoping Chen, Mohamed El Gazzar, Charles E. McCall, Barbara K. Yoza, Jean Y.-Q. Hu, Sue L. Cousart
Publikováno v:
Clinical and Vaccine Immunology. 16:104-110
Transcription factors and chromatin structural modifiers induce clinically relevant epigenetic modifications of blood leukocytes during severe systemic inflammation (SSI) in humans and animals. These changes affect genes with distinct functions, as e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2c1295896be6385cfb55e2189241c575
https://doi.org/10.1128/cvi.00320-08
https://doi.org/10.1128/cvi.00320-08
Publikováno v:
The Journal of Immunology. 177:4080-4085
Using a THP-1 human promonocyte model of endotoxin tolerance that simulates the sepsis leukocyte phenotype, we previously showed that tolerant cells remain responsive to LPS endotoxin with degradation of IκB in the cytosol and nuclear translocation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73637748e12d09a82c17f594f838ef29
https://doi.org/10.4049/jimmunol.177.6.4080
https://doi.org/10.4049/jimmunol.177.6.4080
Publikováno v:
Journal of Biological Chemistry. 266:4173-4179
Tumor necrosis factor alpha (TNF) primes human neutrophils (PMN) for enhanced superoxide (O2-) production if cells are subsequently stimulated with the chemotactic peptide, n-formyl-Met-Leu-Phe (fMLP). fMLP activates phospholipase D to form phosphati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9fc50dbd8b9c05202236a0af2441398f
https://doi.org/10.1016/s0021-9258(20)64303-4
https://doi.org/10.1016/s0021-9258(20)64303-4
Autor:
Xiaoping, Chen, Barbara K, Yoza, Mohamed, El Gazzar, Jean Y Q, Hu, Sue L, Cousart, Charles E, McCall
Publikováno v:
Clinical and vaccine immunology : CVI. 16(1)
Transcription factors and chromatin structural modifiers induce clinically relevant epigenetic modifications of blood leukocytes during severe systemic inflammation (SSI) in humans and animals. These changes affect genes with distinct functions, as e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a767e8ab9b3dc9afe6beb86d33a7a6f3
https://pubmed.ncbi.nlm.nih.gov/19020113
https://pubmed.ncbi.nlm.nih.gov/19020113
Autor:
Mueller Lp, Loeser Cs, Neuhaus K, Li L, Barbara K. Yoza, Chang Mc, Charles E. McCall, Meredith Jw, Sue L. Cousart
Publikováno v:
Shock (Augusta, Ga.). 16(6)
During septic shock, circulating levels of anti-inflammatory mediators are increased relative to those of pro-inflammatory. The reduced capacity of septic shock blood leukocytes in expressing pro-inflammatory genes in response to bacterial lipopolysa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b08262a063a43ab13f9f6faea0660c1
https://pubmed.ncbi.nlm.nih.gov/11770040
https://pubmed.ncbi.nlm.nih.gov/11770040
Publikováno v:
The Journal of biological chemistry. 275(30)
Interleukin-1 receptor-associated kinase (IRAK), a signal transducer for interleukin-1, has also been suggested to participate in the Toll-like receptor-mediated innate immune response to bacterial endotoxin lipopolysaccharide (LPS). Using the human
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37d13fa211c7c45b501ffcdc86210ce4
https://pubmed.ncbi.nlm.nih.gov/10811644
https://pubmed.ncbi.nlm.nih.gov/10811644
Publikováno v:
Shock (Augusta, Ga.). 13(3)
Stimulation of the human promonocytic cell line, THP-1, with endotoxin results in a rapid and transient increase in interleukin 1beta expression. Endotoxin pretreatment of THP-1 cells results in tolerance, characterized by decreased levels of endotox
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0cc440789a285c5583b45d436f5a7c5
https://pubmed.ncbi.nlm.nih.gov/10718382
https://pubmed.ncbi.nlm.nih.gov/10718382
Autor:
Charles E. McCall, Jeffrey Daniel Schmitt, Robert L. Wykle, Joseph T. O'Flaherty, David A. Bass, Sue L. Cousart
Publikováno v:
Biochemical and Biophysical Research Communications. 126:450-456
The protein C kinase activators 1-0-oleoyl, 2-0-acetylglycerol, 12-0-tetradecanoyl phorbol-13-acetate, and mezerein, stimulated deoxyglucose uptake in human neutrophils. The responses were stimulus specific since no effect was noted with the diether
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd1097849c679a09b56a65913f67eb92
https://doi.org/10.1016/0006-291x(85)90626-6
https://doi.org/10.1016/0006-291x(85)90626-6
Publikováno v:
Proceedings of the National Academy of Sciences. 76:5896-5900
The polymorphonuclear leukocyte (PMNL) depends on glucose as a source of energy for motility, chemotaxis, phagocytosis, and bactericidal activity. Activated complement (C5a) at low concentrations stimulates carrier-mediated carbohydrate transport in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a31995b71858f7fb6417fe0a2c8f80d1
https://doi.org/10.1073/pnas.76.11.5896
https://doi.org/10.1073/pnas.76.11.5896
Autor:
Charles E. McCall, Sue L. Cousart, Joseph T. O'Flaherty, Samuel H. Love, Charles L. Swendsen, David A. Bass, L. R. DeChatelet
Publikováno v:
Biochimica et biophysica acta. 640(1)
The influence of extracellular Ca2+ and Mg2+ on the transport of 2-deoxy-[3H]glucose into human polymorphonuclear neutrophils was studied. Omission of these cations from the cell suspensions had little effect on resting hexose uptake. Furthermore, th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d2927cccc873e90725f5717b027d187
https://pubmed.ncbi.nlm.nih.gov/6783085
https://pubmed.ncbi.nlm.nih.gov/6783085