Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Sue Justice"'
Publikováno v:
Endocrine Abstracts.
Autor:
Joëlle Finidori, Richard J. Ross, M. Maamra, S. Von Laue, Sue Justice, X. Y. Shen, P. R. M. Dobson
Publikováno v:
Scopus-Elsevier
The interaction of GH, interleukin (IL)-6 and glucocorticoids is likely to be important in regulating the GH-insulin-like growth factor (IGF)-I axis. The signalling cascades activated by GH and IL-6 appear to be very similar, as demonstrated by studi
Autor:
R. I. G. Holt, Bernard Portmann, Richard J. Ross, J. P. Miell, Sue Justice, Marie-Catherine Postel-Vinay, X. Y. Shen
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism. 83:2532-2538
In cirrhosis, as in other conditions of protein catabolism, there is a state of acquired GH resistance, as defined by high circulating GH levels with low insulin-like growth factor I levels. However, patients with end-stage liver failure respond to s
Autor:
Christian J. Strasburger, Richard J. Ross, S. Pradhananga, Ian Wilkinson, Caroline Touvay, Chantal Soulard, Kin Chuen Leung, Sue Justice, Zida Wu, Eric Ferrandis, Peter J. Artymiuk, Marc Teillot, Jon R. Sayers
Publikováno v:
Nature medicine. 13(9)
Cytokine hormones have a short plasma half-life and require frequent administration. For example, growth hormone replacement involves daily injections. In common with other cytokines, the extracellular domain of the growth hormone receptor circulates
Autor:
Sue Justice, M. Maamra, Sigward Von Laue, Joëlle Finidori, Richard J. Ross, Sylvie Simon, Jonathan Webster, Steven K. Dower
Publikováno v:
The Journal of biological chemistry. 274(21)
We have investigated trafficking of two negative regulators of growth hormone receptor (GHR) signaling: a human, truncated receptor, GHR1-279, and a GH antagonist, B2036. Fluorescent-labeled growth hormone (GH) was rapidly internalized by the full-le