Zobrazeno 1 - 10
of 125
pro vyhledávání: '"Sue Jinks-Robertson"'
Publikováno v:
G3: Genes, Genomes, Genetics, Vol 10, Iss 10, Pp 3821-3829 (2020)
Externí odkaz:
https://doaj.org/article/a073a95d8a9242b7bc8d34b696660427
Autor:
Hannah L. Klein, Giedrė Bačinskaja, Jun Che, Anais Cheblal, Rajula Elango, Anastasiya Epshtein, Devon M. Fitzgerald, Belén Gómez-González, Sharik R. Khan, Sandeep Kumar, Bryan A. Leland, Léa Marie, Qian Mei, Judith Miné-Hattab, Alicja Piotrowska, Erica J. Polleys, Christopher D. Putnam, Elina A. Radchenko, Anissia Ait Saada, Cynthia J. Sakofsky, Eun Yong Shim, Mathew Stracy, Jun Xia, Zhenxin Yan, Yi Yin, Andrés Aguilera, Juan Lucas Argueso, Catherine H. Freudenreich, Susan M. Gasser, Dmitry A. Gordenin, James E. Haber, Grzegorz Ira, Sue Jinks-Robertson, Megan C. King, Richard D. Kolodner, Andrei Kuzminov, Sarah AE Lambert, Sang Eun Lee, Kyle M. Miller, Sergei M. Mirkin, Thomas D. Petes, Susan M. Rosenberg, Rodney Rothstein, Lorraine S. Symington, Pawel Zawadzki, Nayun Kim, Michael Lisby, Anna Malkova
Publikováno v:
Microbial Cell, Vol 6, Iss 1, Pp 1-64 (2019)
Understanding the plasticity of genomes has been greatly aided by assays for recombination, repair and mutagenesis. These assays have been developed in microbial systems that provide the advantages of genetic and molecular reporters that can readily
Externí odkaz:
https://doaj.org/article/9deb4e4edc524ec78e599b9f614eaef3
Autor:
Yee Fang Hum, Sue Jinks-Robertson
Publikováno v:
PLoS Genetics, Vol 14, Iss 3, p e1007302 (2018)
Mitotic recombination can result in loss of heterozygosity and chromosomal rearrangements that shape genome structure and initiate human disease. Engineered double-strand breaks (DSBs) are a potent initiator of recombination, but whether spontaneous
Externí odkaz:
https://doaj.org/article/6c1a1665732d49fca363ca5dd83a4fc5
Publikováno v:
PLoS Genetics, Vol 11, Iss 4, p e1005098 (2015)
Topoisomerase 1 (Top1), a Type IB topoisomerase, functions to relieve transcription- and replication-associated torsional stress in DNA. We investigated the effects of Top1 on genome stability in Saccharomyces cerevisiae using two different assays. F
Externí odkaz:
https://doaj.org/article/17f23bbbec0c4b55942d65b12302244e
Autor:
Puja Yadav, Victoria Harcy, Juan Lucas Argueso, Margaret Dominska, Sue Jinks-Robertson, Nayun Kim
Publikováno v:
PLoS Genetics, Vol 10, Iss 12, p e1004839 (2014)
G-quadruplex or G4 DNA is a non-B secondary DNA structure that comprises a stacked array of guanine-quartets. Cellular processes such as transcription and replication can be hindered by unresolved DNA secondary structures potentially endangering geno
Externí odkaz:
https://doaj.org/article/51d0d0688f224040be6df10ab5e39db8
Publikováno v:
PLoS Genetics, Vol 9, Iss 11, p e1003924 (2013)
RNase H enzymes promote genetic stability by degrading aberrant RNA:DNA hybrids and by removing ribonucleotide monophosphates (rNMPs) that are present in duplex DNA. Here, we report that loss of RNase H2 in yeast is associated with mutations that ext
Externí odkaz:
https://doaj.org/article/8b08bb1a87774344bceb651e54e1ea01
Publikováno v:
PLoS Genetics, Vol 9, Iss 3, p e1003340 (2013)
The contributions of the Sgs1, Mph1, and Srs2 DNA helicases during mitotic double-strand break (DSB) repair in yeast were investigated using a gap-repair assay. A diverged chromosomal substrate was used as a repair template for the gapped plasmid, al
Externí odkaz:
https://doaj.org/article/8ceb155e165341cd981c2578a53f55c1
Autor:
Samantha Shaltz, Sue Jinks-Robertson
Publikováno v:
bioRxiv
A targeted double-strand break introduced into the genome ofSaccharomyces cerevisiaeis repaired by the relatively error-prone nonhomologous-end joining (NHEJ) pathway when homologous recombination is not an option. A ZFN cleavage site was inserted ou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0fa000b54d13b8f1bf1026b454219d9c
https://europepmc.org/articles/PMC10187297/
https://europepmc.org/articles/PMC10187297/
Autor:
Asiya Gusa, Vikas Yadav, Cullen Roth, Jonathan D. Williams, Eva Mei Shouse, Paul Magwene, Joseph Heitman, Sue Jinks-Robertson
Publikováno v:
Proceedings of the National Academy of Sciences. 120
We recently reported transposon mutagenesis as a significant driver of spontaneous mutations in the human fungal pathogen Cryptococcus deneoformans during murine infection. Mutations caused by transposable element (TE) insertion into reporter genes w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::637be70ca804acfb452526cc7bd1e673
https://doi.org/10.1073/pnas.2209831120
https://doi.org/10.1073/pnas.2209831120
Autor:
Sue Jinks-Robertson, Thomas D. Petes
Publikováno v:
Curr Opin Genet Dev
Saccharomyces cerevisiae is at the forefront of defining the major recombination mechanisms/models that repair targeted double-strand breaks during mitosis. Each of these models predicts specific molecular intermediates as well as genetic outcomes. R
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee553b2b7ba946d0cf36ee0674429839
https://doi.org/10.1016/j.gde.2021.07.002
https://doi.org/10.1016/j.gde.2021.07.002