Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Sue G. Griffith"'
Autor:
Gene G. Kinney, Wagner Zago, Martin Koller, Jay Soto, Daniel K. Ness, Michael Grundman, Dale Schenk, Susanne Ostrowitzki, Sue G. Griffith, George Atiee
Publikováno v:
Movement Disorders. 32:211-218
Background: α-Synuclein is a major component of pathologic inclusions that characterize Parkinson's disease. PRX002 is an antibody that targets α-synuclein, and its murine parent antibody 9E4 has been shown in preclinical studies to reduce α-synuc
Autor:
Frank G. Boess, Susanne Ostrowitzki, Beth Safirstein, Joseph Jankovic, Meret Martin-Facklam, Omid Omidvar, Jay Soto, Stuart Isaacson, Tonya K. Marmon, Aaron Ellenbogen, Sue G. Griffith, Joseph F. Quinn, Michael Grundman, Dale Schenk, Daniel Ness, Gene G. Kinney, Wagner Zago, Ira J. Goodman, Martin Koller
Publikováno v:
JAMA neurology. 75(10)
Importance Aggregated α-synuclein is believed to be central to the pathogenesis of Parkinson disease (PD). PRX002/RG7935 (PRX002) is a humanized monoclonal antibody designed to target aggregated forms of α-synuclein, thereby inhibiting neuron-to-ne
Autor:
Dale B, Schenk, Martin, Koller, Daniel K, Ness, Sue G, Griffith, Michael, Grundman, Wagner, Zago, Jay, Soto, George, Atiee, Susanne, Ostrowitzki, Gene G, Kinney
Publikováno v:
Movement disorders : official journal of the Movement Disorder Society. 32(2)
α-Synuclein is a major component of pathologic inclusions that characterize Parkinson's disease. PRX002 is an antibody that targets α-synuclein, and its murine parent antibody 9E4 has been shown in preclinical studies to reduce α-synuclein patholo
Autor:
Sue G. Griffith, Frederique Bard, Michael K. Lee, Kang Hu, Peter Seubert, Kelly Johnson-Wood, Celeste Lee, Ronald Black, Dale Schenk
Publikováno v:
Annals of Neurology. 58:430-435
Serum samples from Alzheimer's disease (AD) patients immunized with Aβ42 (AN1792) were analyzed to determine the induced antibody properties including precise amyloid-β peptide (Aβ) epitopes and amyloid plaque-binding characteristics. The predomin
Autor:
Catherine Bryson, Bruno Sevá Pessôa, Joël Ménard, Richard Gregg, Michel Azizi, A.H. Jan Danser, Ingrid M. Garrelds, Sue G. Griffith, Gerard McGeehan, Richard A. Reeves, Joanna Balcarek
Publikováno v:
Hypertension, 63(5), 942-950. Lippincott Williams & Wilkins
This study compared the pharmacodynamic/pharmacokinetic profile of the new renin inhibitor VTP-27999 in salt-depleted healthy volunteers, administered once daily (75, 150, 300, and 600 mg) for 10 days, versus placebo and 300 mg aliskiren. VTP-27999 w
Autor:
Yuqing Dai, Sue G. Griffith
Publikováno v:
Clinical therapeutics. 26(12)
Background: Several antiepileptic drugs have clinically significant pharmacokinetic interactions with oral contraceptives (OCs) that may result in contraceptive failure. Objective: The aim of this study was to assess the effect of zonisamide on the p
Autor:
Nick C. Fox, Lisa Jenkins, Sue G. Griffith, Martin N. Rossor, Martin Koller, Ronald Black, Sid Gilman
Publikováno v:
Neurobiology of Aging. 25:S84-S85
Autor:
Lisa Jenkins, Jennifer L. Whitwell, VM Anderson, Nick C. Fox, Shona L. Price, Martin N. Rossor, Martin Koller, Richard G. Boyes, Ronald Black, Sue G. Griffith, Josephine Barnes, Basil H. Ridha
Publikováno v:
Neurobiology of Aging. 25:S284
Autor:
Sue G. Griffith, Jean-Marc Orgogozo, Lisa Jenkins, Larry Eisner, Nick C. Fox, Martin Koller, Ronald Black, Françoise Forette, Mercè Boada, Sid Gilman, Louis Kirby
Publikováno v:
Neurobiology of Aging. 25:S84
Autor:
Ronald Black, Sue G. Griffith, Celeste Lee, Michael K. Lee, Dale Schenk, Kang Hu, Peter Seubert, Frederique Bard, Kelly Johnson-Wood
Publikováno v:
Neurobiology of Aging. 25:S588