Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Sue C Nang"'
Autor:
Zhenyu Ma, Sue C. Nang, Zhuo Liu, Jingyi Zhu, Kaijie Mu, Limei Xu, Min Xiao, Lushan Wang, Jian Li, Xukai Jiang
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract The phosphoethanolamine transferase EptA utilizes phosphatidylethanolamine (PE) in the bacterial cell membrane to modify the structure of lipopolysaccharide, thereby conferring antimicrobial resistance on Gram-negative pathogens. Previous st
Externí odkaz:
https://doaj.org/article/608edd1a23834dcfb0d75f0ae88e8a0d
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
Externí odkaz:
https://doaj.org/article/3b1b6d104e0f4d43b7891268d43f224e
Autor:
Mei-Ling Han, Sue C. Nang, Yu-Wei Lin, Yan Zhu, Heidi H. Yu, Hasini Wickremasinghe, Christopher K. Barlow, Darren J. Creek, Simon Crawford, Gauri Rao, Chongshan Dai, Jeremy J. Barr, Kim Chan, Robert Turner Schooley, Tony Velkov, Jian Li
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 20, Iss , Pp 485-495 (2022)
Resistance to the last-line polymyxins is emerging in multidrug-resistant Klebsiella pneumoniae and phage therapy is a promising alternative. However, phage monotherapy often rapidly causes resistance and few studies have examined antibiotic-phage co
Externí odkaz:
https://doaj.org/article/2a60c041def3434ca1a2990b05797555
Publikováno v:
Pharmaceuticals, Vol 16, Iss 10, p 1347 (2023)
Given the urgency due to the rapid emergence of multidrug-resistant (MDR) bacteria, bacteriophages (phages), which are viruses that specifically target and kill bacteria, are rising as a potential alternative to antibiotics. In recent years, research
Externí odkaz:
https://doaj.org/article/abffcbfe0c2f465483e32d5d3d2b67e6
Autor:
Sue C. Nang, Yu-Wei Lin, Aleksandra Petrovic Fabijan, Rachel Y.K. Chang, Gauri G. Rao, Jonathan Iredell, Hak-Kim Chan, Jian Li
Publikováno v:
Clinical Microbiology and Infection. 29:702-709
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2b0ba61dfa926e0da42260308ddcb7c3
https://doi.org/10.1016/j.cmi.2023.01.021
https://doi.org/10.1016/j.cmi.2023.01.021
Autor:
Yi-Yun Liu, Yan Zhu, Hasini Wickremasinghe, Phillip J. Bergen, Jing Lu, Xiao-Qing Zhu, Qiao-Li Zhou, Mohammad Azad, Sue C. Nang, Mei-Ling Han, Tao Lei, Jian Li, Jian-Hua Liu
Publikováno v:
Frontiers in Microbiology, Vol 11 (2020)
Rapid dissemination of the plasmid-born polymyxin resistance gene mcr-1 poses a critical medical challenge. MCR-1 expression is tightly controlled and imposes a fitness cost on the bacteria. We used growth studies and metabolomics to examine growth a
Externí odkaz:
https://doaj.org/article/87fb258c23a4447abfcf8150515d5e03
Publikováno v:
Antimicrobial Agents and Chemotherapy. 67
Recurrent urinary tract infections (rUTI) are common in kidney transplant recipients (KTR) and are associated with multidrug resistance and increased morbidity/mortality. Novel antibiotic alternatives to reduce UTI recurrence are critically needed.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5c587973673f3b3237c5450dc4e97c63
https://doi.org/10.1128/aac.00037-23
https://doi.org/10.1128/aac.00037-23
Publikováno v:
Microbiology Spectrum. 11
As infections caused by multidrug-resistant “superbugs” are increasing globally, polymyxins are often the only viable therapeutic option. Alarmingly, the wide spread of the plasmid-mediated polymyxin resistance gene mcr-1 is restricting the clini
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::085e7965c8aa49a0c8ad4545cadbc983
https://doi.org/10.1128/spectrum.03223-22
https://doi.org/10.1128/spectrum.03223-22
Autor:
Sue C. Nang, Jing Lu, Heidi H. Yu, Hasini Wickremasinghe, Mohammad A. K. Azad, Meiling Han, Jinxin Zhao, Gauri Rao, Phillip J. Bergen, Tony Velkov, Norelle Sherry, David T. McCarthy, Saima Aslam, Robert T. Schooley, Benjamin P. Howden, Jeremy J. Barr, Yan Zhu, Jian Li
Phage therapy is a promising alternative treatment for multidrug-resistant bacterial infections. Unfortunately, phage resistance represents a major barrier hindering the clinical utility. Mechanistic insights into bacterial phage defense mechanisms a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::665a18723337dce6ac406c39f73b45db
https://doi.org/10.1101/2022.11.14.516531
https://doi.org/10.1101/2022.11.14.516531
Publikováno v:
Pharmacological Reviews
Antibiotic resistance is a major global health challenge and, worryingly, several key Gram negative pathogens can become resistant to most currently available antibiotics. Polymyxins have been revived as a last-line therapeutic option for the treatme
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2452be74b8ce558204ac30c121fea7ab
http://europepmc.org/articles/PMC7911091
http://europepmc.org/articles/PMC7911091