Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Sue, Lightman"'
Autor:
Ahmed Al-Janabi, PhD, FRCOphth, Lazha Sharief, PhD, FRCOphth, Noura Al Qassimi, MD, Yi-Hsing Chen, MD, PhD, Tao Ding, PhD, Gareth Ambler, PhD, Dimitris Ladas, MD, PhD, Sue Lightman, PhD, FRCOphth, Oren Tomkins-Netzer, MD, PhD
Publikováno v:
Ophthalmology Science, Vol 3, Iss 4, Pp 100333- (2023)
Objective: To assess the efficacy of simvastatin 80 mg/day versus placebo in patients with noninfectious nonanterior uveitis receiving prednisolone ≥ 10 mg/day. Design: Randomized, double-masked, controlled trial. Subjects: Adult patients with noni
Externí odkaz:
https://doaj.org/article/5c1b15bcfe6144bda981646bdef80dd0
Autor:
Yi Hsing Chen, Malihe Eskandarpour, Xiaozhe Zhang, Grazyna Galatowicz, John Greenwood, Sue Lightman, Virginia Calder
Publikováno v:
Journal of Neuroinflammation, Vol 18, Iss 1, Pp 1-13 (2021)
Abstract Background The integrin VLA-4 (α4β1) plays an important role in leukocyte trafficking. This study investigated the efficacy of a novel topical α4β1 integrin inhibitor (GW559090, GW) in a mouse model for non-infectious posterior uveitis (
Externí odkaz:
https://doaj.org/article/9de152e6d08040b697c82aa3893728fb
Autor:
Xia-Ni Wu, Yi-Hsing Chen, Lazha Sharief, Ahmed Al-Janabi, Nura Al Qassimi, Sue Lightman, Oren Tomkins-Netzer
Publikováno v:
Antibiotics, Vol 11, Iss 7, p 843 (2022)
Background: Examining the effect of antibiotic resistance, use of intravitreal antibiotics and systemic corticosteroids on visual outcome of eyes with acute endophthalmitis. Methods: We included 226 eyes with acute endophthalmitis, treated using a st
Externí odkaz:
https://doaj.org/article/a6a970a820dd400dab7e7528ae3da825
Publikováno v:
Uveitis Management ISBN: 9789811251467
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0e028832ef51120b99c54ecdc0cef126
https://doi.org/10.1142/9789811251474_0012
https://doi.org/10.1142/9789811251474_0012
Autor:
Rose M. Gilbert, Xiaozhe Zhang, Robert D. Sampson, Michael R. Ehrenstein, Dao X. Nguyen, Mahid Chaudhry, Charles Mein, Nadiya Mahmud, Grazyna Galatowicz, Oren Tomkins-Netzer, Virginia L. Calder, Sue Lightman
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
BackgroundNon-infectious uveitis can cause chronic relapsing and remitting ocular inflammation, which may require high dose systemic immunosuppression to prevent severe sight loss. It has been classically described as an autoimmune disease, mediated
Externí odkaz:
https://doaj.org/article/b42b99a840f043ffb206c156e89239dc
Publikováno v:
Journal of Ophthalmology, Vol 2016 (2016)
With the introduction of aflibercept, eyes with neovascular age-related macular degeneration (AMD) not responding well to injections of ranibizumab or bevacizumab can be switched to treatment with aflibercept. We carried out a meta-analysis to analyz
Externí odkaz:
https://doaj.org/article/dea894a2e3924a16a8feecee25bea52f
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 503, p 503 (2022)
International Journal of Molecular Sciences
International Journal of Molecular Sciences
Non-infectious uveitis (NIU) is an inflammatory eye disease initiated via CD4+ T-cell activation and transmigration, resulting in focal retinal tissue damage and visual acuity disturbance. Cell adhesion molecules (CAMs) are activated during the infla
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c4bbb186542775dcb988b369fd681d8
https://www.mdpi.com/1422-0067/23/1/503
https://www.mdpi.com/1422-0067/23/1/503
Publikováno v:
Case Reports in Ophthalmology, Vol 3, Iss 3, Pp 286-290 (2012)
We report a patient with necrotising scleritis in whom infliximab was used for short-term steroid-sparing while rituximab took effect. This enabled disease control without requiring an extended period of high-dose corticosteroid administration or the
Externí odkaz:
https://doaj.org/article/ab0e72c367234fb58180a2b9f09b681d
Publikováno v:
International Journal of Molecular Sciences
Non-infectious uveitis (NIU) is a potentially sight-threatening disease. Effector CD4+ T cells, especially interferon-γ-(IFNγ) producing Th1 cells and interleukin-17-(IL-17) producing Th17 cells, are the major immunopathogenic cells, as demonstrate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d1a629ade38a99babc6cbabb28cdd944
https://pubmed.ncbi.nlm.nih.gov/34502490
https://pubmed.ncbi.nlm.nih.gov/34502490
Publikováno v:
Case Reports in Ophthalmology, Vol 3, Iss 3, Pp 283-285 (2012)
We present the first reported case of acute endophthalmitis due to Rhizobium radiobacter after an intravitreal injection of ranibizumab for neovascular age-related macular degeneration.
Externí odkaz:
https://doaj.org/article/db81d87bf95a4abbaa91ca6d38b7fa01