Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Sudipa Saha Roy"'
Autor:
Sudipa Saha Roy, Ratna K. Vadlamudi
Publikováno v:
International Journal of Breast Cancer, Vol 2012 (2012)
Metastatic breast cancer is a life-threatening stage of cancer and is the leading cause of death in advanced breast cancer patients. Estrogen signaling and the estrogen receptor (ER) are implicated in breast cancer progression, and the majority of th
Externí odkaz:
https://doaj.org/article/44821cd26f1541e48315d27874318e6b
Autor:
Ratna K. Vadlamudi, Rajeshwar Rao Tekmal, Sudipa Saha Roy, Valerie Cortez, Samaya Rajeshwari Krishnan, Gangadhara R. Sareddy, Vijay K. Gonugunta
PDF 385K, mTOR inhibitors reduce the tamoxifen driven PELP1-mediated subcutaneous xenograft tumor growth.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09c48fd618d7431a11332a3beb34898c
https://doi.org/10.1158/1535-7163.22500966.v1
https://doi.org/10.1158/1535-7163.22500966.v1
Autor:
Ratna K. Vadlamudi, Rajeshwar Rao Tekmal, Sudipa Saha Roy, Valerie Cortez, Samaya Rajeshwari Krishnan, Gangadhara R. Sareddy, Vijay K. Gonugunta
PDF - 106K, Synergistic effect of mTOR inhibitor and tamoxifen on therapy resistant cells.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c0ff8ffcde1547be8a472d577b55cef
https://doi.org/10.1158/1535-7163.22500969.v1
https://doi.org/10.1158/1535-7163.22500969.v1
Autor:
Ratna K. Vadlamudi, Rajeshwar Rao Tekmal, Sudipa Saha Roy, Valerie Cortez, Samaya Rajeshwari Krishnan, Gangadhara R. Sareddy, Vijay K. Gonugunta
PDF - 226K, PELP1 down regulation or upregulation alters mTOR signaling and PELP1 interacts with mTOR.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ee2a581d512536df04a09826cfa4beb
https://doi.org/10.1158/1535-7163.22500975
https://doi.org/10.1158/1535-7163.22500975
Autor:
Ratna K. Vadlamudi, Rajeshwar Rao Tekmal, Sudipa Saha Roy, Valerie Cortez, Samaya Rajeshwari Krishnan, Gangadhara R. Sareddy, Vijay K. Gonugunta
Proline, Glutamic acid-, and Leucine-rich Protein 1 (PELP1) is a proto-oncogene that modulates estrogen receptor (ER) signaling. PELP1 expression is upregulated in breast cancer, contributes to therapy resistance, and is a prognostic marker of poor s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::68f3572be843171d8ce0558f8cdf8cff
https://doi.org/10.1158/1535-7163.c.6536649.v1
https://doi.org/10.1158/1535-7163.c.6536649.v1
Autor:
Ratna K. Vadlamudi, Rajeshwar Rao Tekmal, Sudipa Saha Roy, Valerie Cortez, Samaya Rajeshwari Krishnan, Gangadhara R. Sareddy, Vijay K. Gonugunta
PDF - 115K, mTOR inhibitors reduce proliferation and promote apoptosis of PELP1-WT driven tumors.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62fb5ea4d48c7aa5e91947a0d54eabb7
https://doi.org/10.1158/1535-7163.22500972
https://doi.org/10.1158/1535-7163.22500972
Autor:
Joo L. Ong, Sudipa Saha Roy, Rajiv K. Satsangi, Arpan Satsangi, Beth A. Goins, Anthony W. Tolcher, Ratna K. Vadlamudi
Publikováno v:
Biomaterials. 59:88-101
Breast cancer is the leading cause of cancer deaths among women. Paclitaxel (PTX), an important breast cancer medicine, exhibits reduced bioavailability and therapeutic index due to high hydrophobicity and indiscriminate cytotoxicity. PTX encapsulati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d6531a00be7cc0e985339fd55ca91bbe
https://doi.org/10.1016/j.biomaterials.2015.03.039
https://doi.org/10.1016/j.biomaterials.2015.03.039
Autor:
Binoj C. Nair, Gangadhara R. Sareddy, Ganesh V. Raj, Ratna K. Vadlamudi, Yan Peng, Sudipa Saha Roy, Takayoshi Suzuki, Mohan Natarajan, Samaya Rajeshwari Krishnan
Publikováno v:
Breast Cancer Research and Treatment. 150:487-499
Triple-negative breast cancer (TNBC), the most aggressive breast cancer subtype, occurs in younger women and is associated with poor prognosis. Gain-of-function mutations in TP53 are a frequent occurrence in TNBC and have been demonstrated to repress
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2cc014ea2b4f531e2924c6e16ac044eb
https://doi.org/10.1007/s10549-015-3339-x
https://doi.org/10.1007/s10549-015-3339-x
Autor:
Sudipa Saha Roy, Ratna K. Vadlamudi, Vijay K. Gonugunta, Valerie Cortez, Rajeshwar Rao Tekmal, Gangadhara R. Sareddy, Samaya Rajeshwari Krishnan
Publikováno v:
Molecular Cancer Therapeutics. 13:1578-1588
Proline, Glutamic acid-, and Leucine-rich Protein 1 (PELP1) is a proto-oncogene that modulates estrogen receptor (ER) signaling. PELP1 expression is upregulated in breast cancer, contributes to therapy resistance, and is a prognostic marker of poor s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a3901e89ba63f224c94950cbc474f85
https://doi.org/10.1158/1535-7163.mct-13-0877
https://doi.org/10.1158/1535-7163.mct-13-0877
Publikováno v:
Cancer Research. 73:P4-16
BACKGROUND: Breast cancer is the 2nd most common cause of cancer deaths in women. Chemotherapy is an important treatment modality. Yet, delivery of drugs such as paclitaxel (PTX) to cancer cells remains a challenge, mainly due to a drug's low solubil
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1fde8b2ebc1d8dcb6fa41d69f14aa5ec
https://doi.org/10.1158/0008-5472.sabcs13-p4-16-10
https://doi.org/10.1158/0008-5472.sabcs13-p4-16-10