Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Sudhir Pai Kasturi"'
Autor:
Xin Bing, Tyler Lovelace, Florentina Bunea, Marten Wegkamp, Sudhir Pai Kasturi, Harinder Singh, Panayiotis V. Benos, Jishnu Das
Publikováno v:
Patterns, Vol 3, Iss 5, Pp 100473- (2022)
Summary: High-dimensional cellular and molecular profiling of biological samples highlights the need for analytical approaches that can integrate multi-omic datasets to generate prioritized causal inferences. Current methods are limited by high dimen
Externí odkaz:
https://doaj.org/article/5dd6368ebad64446982ba499f1247b52
Autor:
Traci Legere, Pradeep B. J. Reddy, Korey A. Walter, Bali Pulendran, Prabhu S. Arunachalam, Shankar Subramaniam, Florian Wimmers, Madeleine K D Scott, Celia C. LaBranche, Bertrand Z. Yeung, John P. Vasilakos, Venkata S. Bollimpelli, Samantha L. Burton, Sailaja Gangadhara, Sudhir Pai Kasturi, Shakti Gupta, Cynthia A. Derdeyn, Caroline Petitdemange, Pamela A. Kozlowski, David C. Montefiori, Tiffany M. Styles, Thomas J. Ketas, John P. Moore, Chil Yong Kang, Rama Rao Amara, Eric Hunter, George M. Shaw, Purvesh Khatri, Mark A. Tomai, Anthony Tsai, David Masopust, Vineet Joag, Clare F. Quarnstrom, Tysheena P. Charles
Publikováno v:
Nature Medicine
Recent efforts toward an HIV vaccine focus on inducing broadly neutralizing antibodies, but eliciting both neutralizing antibodies (nAbs) and cellular responses may be superior. Here, we immunized macaques with an HIV envelope trimer, either alone to
Autor:
Xin Bing, Tyler Lovelace, Florentina Bunea, Marten Wegkamp, Sudhir Pai Kasturi, Harinder Singh, Panayiotis V. Benos, Jishnu Das
Publikováno v:
Patterns (New York, N.Y.). 3(5)
High-dimensional cellular and molecular profiling of biological samples highlights the need for analytical approaches that can integrate multi-omic datasets to generate prioritized causal inferences. Current methods are limited by high dimensionality
Autor:
Guido Ferrari, Neeta Shenvi, Thomas H. Vanderford, Susan Pereira Ribeiro, Wen-Hsiang Chen, David C. Montefiori, Talha Abid, Alessandro Sette, Daniela Weiskopf, Debashis Dutta, Katharine Floyd, Shelly Wang, Dieter Mielke, Sudhir Pai Kasturi, Georgia D. Tomaras, Pamela A. Kozlowski, Celia C. LaBranche, Maria Pino, Jungsoon Lee, Sherrie Jean, Venkata Viswanadh Edara, Xiaoying Shen, Justin Pollara, Justin C Smith, Mirko Paiardini, Rafick Pierre Sekaly, Fawn Connor-Stroud, Joyce Cohen, Gabriela Pacheco-Sanchez, Hongmei Gao, Zhuyun Liu, Christopher B. Fox, Sanjeev Gumber, Junfei Wei, Nathan Eisel, Maria Elena Bottazzi, Rachelle L. Stammen, Jennifer S. Wood, Shannon Kirejczyk, Bin Zhan, Muhammad Bilal Latif, Peter J. Hotez, Kirk Easley, Ulrich Strych, Jeroen Pollet, Mehul S. Suthar, Mark A. Tomai
Publikováno v:
Science immunology. 6(61)
Ongoing SARS-CoV-2 vaccine development is focused on identifying stable, cost-effective, and accessible candidates for global use, specifically in low and middle-income countries. Here, we report the efficacy of a rapidly scalable, novel yeast expres
Autor:
Amit A. Upadhyay, Sudhir Pai Kasturi, Elise G. Viox, Steven E. Bosinger, Ernestine A. Mahar, Michael N. Sayegh, Sanjeev Gumber, Justin L. Harper, Arun K. Boddapati, Sijia Tao, Shelly Wang, Rebecca D. Levit, Thomas H. Vanderford, Michelle Y.H. Lee, Shannon Kirejczyk, Sherrie Jean, Keivan Zandi, Susan Pereira Ribeiro, Carly E. Starke, Lanfang Wang, Daniela Weiskopf, Maria Pino, Joyce Cohen, Timothy N. Hoang, Tristan R. Horton, Gregory K. Tharp, Jesse J. Waggoner, Kathleen Busman-Sahay, Anne Piantadosi, Olivia M. Delmas, Kathryn L. Pellegrini, Jennifer S. Wood, Jacob D. Estes, Peter D. Filev, Mirko Paiardini, Rachelle L. Stammen, Elizabeth N. Beagle, Zachary Strongin, Raymond F. Schinazi, Rafick Pierre Sekaly, Kimberly A. Cooney, Fawn Connor-Stroud, Hilmi Al Shakhshir
Publikováno v:
bioRxiv
Effective therapeutics aimed at mitigating COVID-19 symptoms are urgently needed. SARS-CoV-2 induced hypercytokinemia and systemic inflammation are associated with disease severity. Baricitinib, a clinically approved JAK1/2 inhibitor with potent anti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb6f3ad475da4ad3af4b09b02cb47beb
https://doi.org/10.1101/2020.09.16.300277
https://doi.org/10.1101/2020.09.16.300277
Autor:
Zachary Strongin, Timothy N. Hoang, Rebecca D. Levit, Shelly Wang, Sherrie Jean, Kimberly A. Cooney, Susan Pereira Ribeiro, Mirko Paiardini, Lanfang Wang, Gregory K. Tharp, Rafick Pierre Sekaly, Michael Nekorchuk, Elise G. Viox, Raymond F. Schinazi, Justin L. Harper, Jacob D. Estes, Steven E. Bosinger, Michelle Y.H. Lee, Hilmi Al-Shakhshir, Rachelle L. Stammen, Kathleen Busman-Sahay, Arun K. Boddapati, Daniela Weiskopf, Sijia Tao, Anne Piantadosi, Guido Silvestri, Kathryn L. Pellegrini, Maria Pino, Michael N. Sayegh, Fawn Connor-Stroud, Thomas H. Vanderford, Tristan R. Horton, Jesse J. Waggoner, Joyce Cohen, Olivia M. Delmas, Jennifer S. Wood, Peter D. Filev, Carly E. Starke, Amit A. Upadhyay, Sudhir Pai Kasturi, Ernestine A. Mahar, Shannon Kirejczyk, Elizabeth N. Beagle, Sanjeev Gumber, Keivan Zandi
Publikováno v:
bioRxiv
article-version (status) pre
article-version (number) 1
Cell
article-version (status) pre
article-version (number) 1
Cell
SARS-CoV-2 induced hypercytokinemia and inflammation are critically associated with COVID-19 disease severity. Baricitinib, a clinically approved JAK1/2 inhibitor, is currently being investigated in COVID-19 clinical trials. Here, we investigated the
Autor:
Guido Silvestri, Patricia van der Woude, Ata Ur Rasheed Mohammed, Dennis R. Burton, Anapatricia Garcia, Colin Havenar-Daughton, Michela Locci, Diane G. Carnathan, Samantha M. Reiss, Steven W. de Taeye, Bali Pulendran, Alba Torrents de la Peña, Marit J. van Gils, Jessica Huang, Devin Sok, Khoa M. Le, Jennifer S. Wood, Sudhir Pai Kasturi, Sanjeev Gumber, Rafi Ahmed, Sandy L. Rosales, Shane Crotty, Bryan Briney, Grégory Seumois, Matthias Pauthner, Rogier W. Sanders, Kirti Kaushik, John P. Moore
Publikováno v:
Cell reports, 17(9), 2195-2209. Cell Press
SummaryGenerating tier 2 HIV-neutralizing antibody (nAb) responses by immunization remains a challenging problem, and the immunological barriers to induction of such responses with Env immunogens remain unclear. Here, some rhesus monkeys developed au
Autor:
Bali Pulendran, Traci Legere, Tiffany M. Styles, Peter T. Hraber, Lori M Spicer, Pradeep B. J. Reddy, Tysheena P. Charles, Cynthia A. Derdeyn, Sailaja Gangadhara, Vijayakumar Velu, Sudhir Pai Kasturi, Eric Hunter, Samantha L. Burton, Rama Rao Amara
Publikováno v:
Journal of Virology. 93
The goals of preclinical HIV vaccine studies in nonhuman primates are to develop and test different approaches for their ability to generate protective immunity. Here, we compared the impact of 7 different vaccine modalities, all expressing the HIV-1
Autor:
John P. Vasilakos, Rafiq Nabi, Dan H. Barouch, Yevgeniy Kovalenkov, Sudhir Pai Kasturi, Pamela A. Kozlowski, Traci Legere, Bali Pulendran, Jonathan W. Yewdell, David C. Montefiori, Jens Wrammert, James S. Gibbs, Parin Patel, Lori M. Spicer, Mark A. Tomai, Pradeep B. J. Reddy, Eric Hunter, Barton F. Haynes, C. Yong Kang, Clare F. Quarnstrom, David Masopust, Caroline Petitdemange, Cynthia A. Derdeyn, Celia C. LaBranche, Francois Villinger, Rama Rao Amara
Publikováno v:
JCI insight. 4(4)
Antibodies and cytotoxic T cells represent 2 arms of host defense against pathogens. We hypothesized that vaccines that induce both high-magnitude CD8(+) T cell responses and antibody responses might confer enhanced protection against HIV. To test th
Autor:
Bali Pulendran, Samantha M. Reiss, Guido Silvestri, Kayla Kendric, Alba Torrents de la Peña, Jennifer M. Dan, Shane Crotty, Sudhir Pai Kasturi, Jennifer E. Wu, Marcella Bothwell, Colin Havenar-Daughton, Diane G. Carnathan, Rogier W. Sanders
Publikováno v:
Journal of immunology (Baltimore, Md., 197(3), 994-1002. American Association of Immunologists
A range of current candidate AIDS vaccine regimens are focused on generating protective HIV-neutralizing Ab responses. Many of these efforts rely on the rhesus macaque animal model. Understanding how protective Ab responses develop and how to increas