Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Sudhir Nambiar"'
Autor:
Helen F. Sneddon, Frank Roschangar, Sudhir Nambiar, Seth D. Ribe, Jeremy P. Scott, Michael E. Kopach, Scott V. Plummer, Guy R. Humphrey, Juan Colberg, Alina Borovika, Christiana Briddell, Isamir Martinez, Cisco Bee, Stefan G. Koenig
Publikováno v:
ACS Sustainable Chemistry & Engineering. 7:16937-16951
In an effort to improve sustainability and reduce the cost of goods for active pharmaceutical ingredients (APIs), pharma companies have partnered on varying portions of their supply chain with cont...
Autor:
Goverdhan Gilla, Suresh M. Doke, Santosh Kumar Ghosh, Sudhir Nambiar, L. Nagaprasada Rao, Sudhir Mittapalli, Pramod Sawant
Publikováno v:
Journal of Molecular Structure. 1203:127406
Prothioconazole is a broad spectrum anti-fungal agent of triazolinthione family; it has been widely used in crop protection especially in cereals. To date, only the crystal structure of form II and p-xylene solvates were reported, as per our knowledg
Autor:
Sulur G. Manjunatha, Sreekanth Bachu, Mohana Kumari, Sridharan Ramasubramanian, Ramachandra Puranik, Sudhir Nambiar, Vibha Gautam
Publikováno v:
Tetrahedron Letters. 55:6441-6446
A simple and efficient methodology for the synthesis of 5-amino-quinazolines and 4-amino-indoles via Semmler–Wolff aromatisation reaction has been carried out. The oximation of keto intermediates followed by Semmler–Wolff aromatisation using acet
Autor:
Ramachandra Puranik, Sulur G. Manjunatha, Sagar Bhagat, Gutala Phaneendra, Sudhir Nambiar, Ravindran Prakash, M. Suresh Babu, Vibha Gautam, Veera Babu Kagita, Sridharan Ramasubramanian, Jaikumar Keshwan
Publikováno v:
Tetrahedron Letters. 55:4943-4947
A simple synthetic approach has been developed towards one pot synthesis of 2-imidazolines under mild acidic conditions from N -acetyl glucosamine via reductive amination followed by dehydrative cyclization. Synthetic studies were explored in detail
Autor:
Sulur G. Manjunath, Sridhran R, Sudhir Nambiar, Vinod Kumar Ch, Suresh Kumar Sythana, Smitha Chitrapadi, Gajanan Tammanna Kantikar, Avipsa Ghosh, Paramashivappa Rangappa
Publikováno v:
Organic Process Research & Development. 18:947-951
The development of a convenient, safe and scalable process for AZD8329 manufacturing is reported here. Synthesis was achieved in a two-step telescopic process with an excellent overall yield of 75%. In the first step enamine (6) was synthesized with
Autor:
U. Santhosh, Marijan Stefinovic, Jnaneshwara Kindel, Yogesh M. Kshirsagar, R. Sridharan, K. Venkatesan, Sudhir Nambiar, Garnet E. Howells, Debasis Hazra, David Ennis, Sulur G. Manjunatha
Publikováno v:
Organic Process Research & Development. 18:1802-1806
This report describes the development and scale up of the synthesis of oxaisoxazolidinone 1, a significant synthon in the synthesis of the MRSA development compound AZD5847. Studies were carried out to ensure a short-term, risk based preparation of 9
Autor:
Sulur G. Manjunatha, Andiappan Murugan, Ravi Ramakrishnan, Sreekanth Bachu, Sridharan Ramasubramanian, Sudhir Nambiar, Vasantha Krishna Kadambar, Venkata Rao Torlikonda, Sajan George, Chandrasekhara Reddy
Publikováno v:
Organic Process Research & Development. 18:646-651
An efficient and scalable synthesis of AZD3264 is described in which the differential reactivities of various halogen atoms have been employed. The process involves five linear chemical steps with three isolated stages starting from commercially avai
Autor:
S. Raghavender, Suryanarayan Cherukuvada, Ashwini Nangia, Sulur G. Manjunatha, Swarupa Gangavaram, N. Rajesh Goud, Sharmistha Pal, Sudhir Nambiar, U. B. Rao Khandavilli
Publikováno v:
CrystEngComm. 16:4842-4852
Novel sodium and potassium salts of the poorly soluble loop diuretic drug furosemide were prepared with the intent of improving drug solubility and bioavailability. Furo–Na salt was obtained as a trihydrate upon crystallization from aqueous NaOH so
Autor:
Diane Grob Schmidt, H. N. Cheng, Agnes M. Rimando, Bradley D. Miller, Judith L. Benham, Joseph S. Francisco, Jay Siegel, Thomas Connelly, Angela Phillips Diaz, Deva Hupaylo, Ellene Tratras Contis, Joseph M. DeSimone, Alexander Sachse, Javier Garcia Martinez, Jo Shen, Sundeep Dugar, Abhinav Dhandia, Thais Guaratini, Sudhir Nambiar, Frank Jaksch, Sharon V. Vercellotti, John R. Vercellotti, Daniel Daly, Judith C. Giordan
Publikováno v:
Journal of Thermal Analysis and Calorimetry. 115:2261-2268
Thermal techniques, differential scanning cal- orimetry (DSC), and hot stage microscopy (HSM) have been used to study the interactions between furosemide and caffeine that are known to form a 1:1 cocrystal. This sys- tem has been used as an example t