Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Sudhir J.A. D'Souza"'
Autor:
Tames Irvine, Lina Dagnino, Gilles A. Lajoie, Kodi S. Ravichandran, Sudhir J.A. D'Souza, Ernest Ho, Gregory J.A. Vilk
Publikováno v:
Physiology and Pharmacology Publications
Cell polarization is a key prerequisite for directed migration during development, tissue regeneration, and metastasis. Integrin-linked kinase (ILK) is a scaffold protein essential for cell polarization, but very little is known about the precise mec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1597b098d0b46af54e3dd295dc85ed45
https://doi.org/10.1091/mbc.e09-01-0050
https://doi.org/10.1091/mbc.e09-01-0050
Publikováno v:
Molecular Biology of the Cell. 16:4084-4095
Integrin-linked kinase (ILK) is a multidomain protein involved in cell motility and cell-extracellular matrix interactions. ILK is found in integrin-containing focal adhesions in undifferentiated primary epidermal keratinocytes. Induction of keratino
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5d170c586148b8e52574676af7c79fe
https://doi.org/10.1091/mbc.e05-02-0087
https://doi.org/10.1091/mbc.e05-02-0087
Autor:
Agnieszka Pajak, Luke Martin-McCaffrey, David P. Siderovski, Sudhir J.A. D'Souza, Francis S. Willard, Lina Dagnino
Publikováno v:
Cell Cycle. 4:953-960
Heterotrimeric G-proteins and their regulators are emerging as important players in modulating microtubule polymerization dynamics and in spindle force generation during cell division in C. elegans, D. melanogaster and mammals. We recently demonstrat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72459a4e36f7c4333686cf3497efe022
https://doi.org/10.4161/cc.4.7.1787
https://doi.org/10.4161/cc.4.7.1787
Autor:
Randall J. Kimple, Agnieszka Pajak, Lina Dagnino, David P. Siderovski, Antonio J. Oliveira-dos-Santos, Andrew J. Watson, Sudhir J.A. D'Souza, Francis S. Willard, Luke Martin-McCaffrey, David R. C. Natale, Josef M. Penninger, Bryan E. Snow
Publikováno v:
Obstetrics & Gynaecology Publications
Heterotrimeric G protein α subunits, RGS proteins, and GoLoco motif proteins have been recently implicated in the control of mitotic spindle dynamics in C. elegans and D. melanogaster. Here we show that “regulator of G protein signaling-14” (RGS
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9275b01220a8ba40ad25a634c0d4aa4f
Publikováno v:
Obstetrics & Gynaecology Publications
Mitogen-activated protein kinase (MAPK) pathways mediate some important cellular processes and are likely to also regulate preimplantation development. The role of p38 MAP kinase signaling during murine preimplantation development was investigated in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c996249785456631abda44b38387b6fd
https://doi.org/10.1016/j.ydbio.2003.12.011
https://doi.org/10.1016/j.ydbio.2003.12.011
Autor:
J. Geoffrey Pickering, Sudhir J.A. D'Souza, Caroline Van Den Diepstraten, Bosco M.C. Chan, Shaohua Li
Publikováno v:
The American Journal of Pathology. 163:1045-1056
Assembly of collagen into fibrils is widely studied as a spontaneous and entropy-driven process. To determine whether vascular smooth muscle cells (SMCs) impact the formation of collagen fibrils, we microscopically tracked the conversion of soluble t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f90bd41ffa94ac5e25012e11e7e5aa75
https://doi.org/10.1016/s0002-9440(10)63464-5
https://doi.org/10.1016/s0002-9440(10)63464-5
Autor:
Katalin Szászi, Ravi Ramjeesingh, Sergio Grinstein, Kazuyoshi Kurashima, Sudhir J.A. D'Souza, John Orlowski
Publikováno v:
Journal of Biological Chemistry. 274:29843-29849
The epithelial isoform of the Na(+)/H(+) exchanger, NHE3, associates with at least two related regulatory factors called NHERF1/EBP50 and NHERF2/TKA-1/E3KARP. These factors in addition interact with the cytoskeletal protein ezrin, which in turn binds
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::559c5ea861b99651a2b53ba8ba94c90b
https://doi.org/10.1074/jbc.274.42.29843
https://doi.org/10.1074/jbc.274.42.29843
Publikováno v:
Journal of Biological Chemistry. 273:2044-2051
Sorting of secretory cargo and retrieval of components of the biosynthetic pathway occur at the trans-Golgi network (TGN). The pH within the TGN is thought to be an important determinant of these functions. However, studies of the magnitude and regul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::66def494f46ce7673d2e6b0e8c5ca321
https://doi.org/10.1074/jbc.273.4.2044
https://doi.org/10.1074/jbc.273.4.2044
Autor:
John Orlowski, Sudhir J.A. D'Souza, Ken Teter, Frank H. Yu, Gergely L. Lukacs, Karl Skorecki, Ana Garcia-Cabado, Hsiao-Ping H. Moore, Sergio Grinstein
Publikováno v:
Journal of Biological Chemistry. 273:2035-2043
Na+/H+ exchangers (NHEs) mediate electroneutral exchange of Na+ for H+ and thereby play a central role in pH regulation and Na+ homeostasis. NHE3, the predominant epithelial isoform, is found in apical membranes of renal and intestinal epithelial cel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18c1dbeb52070958975cddf78434d0c3
https://doi.org/10.1074/jbc.273.4.2035
https://doi.org/10.1074/jbc.273.4.2035
Publikováno v:
Paediatrics Publications
Molecular Biology of the Cell
Molecular Biology of the Cell
Inactivation of integrin-linked kinase in the stem cells of the hair follicle bulge results in impaired skin regeneration after injury but does not affect hair follicle entry into anagen.
Integrin-linked kinase (ILK) is key for normal epidermal
Integrin-linked kinase (ILK) is key for normal epidermal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39c00fdb1decb977fbbb612967e4279d
https://ir.lib.uwo.ca/paedpub/1045
https://ir.lib.uwo.ca/paedpub/1045
