Zobrazeno 1 - 10
of 71
pro vyhledávání: '"Sudheer Ravuri"'
Autor:
Zhenhan Deng, Xueqin Gao, Hajime Utsunomiya, Justin W. Arner, Joseph J. Ruzbarsky, Matthieu Huard, Sudheer Ravuri, Marc J. Philippon, Johnny Huard
Publikováno v:
Bone Reports, Vol 16, Iss , Pp 101526- (2022)
Background and aims: Previous work has shown that oral losartan can enhance microfracture-mediated cartilage repair in a rabbit osteochondral defect injury model. In this study, we aimed to determine whether oral losartan would have a detrimental eff
Externí odkaz:
https://doaj.org/article/0242b331d96d40f58cb59af92f991d5d
Publikováno v:
Bioengineering, Vol 8, Iss 4, p 46 (2021)
It is widely accepted that chondral defects in articular cartilage of adult joints are never repaired spontaneously, which is considered to be one of the major causes of age-related degenerative joint disorders, such as osteoarthritis. Since mobiliza
Externí odkaz:
https://doaj.org/article/c628d9d7314c489bb49d5c0444a85cd3
Publikováno v:
Metabolites, Vol 11, Iss 4, p 247 (2021)
Duchenne muscular dystrophy (DMD) is a degenerative muscle disorder characterized by a lack of dystrophin expression in the sarcolemma of muscle fibers. DMD patients acquire bone abnormalities including osteopenia, fragility fractures, and scoliosis
Externí odkaz:
https://doaj.org/article/ef34f1af054149c281731c09788788f1
Autor:
Jae Sung Lee, Ping Guo, Katarina Klett, MacGregor Hall, Krishna Sinha, Sudheer Ravuri, Johnny Huard, William L. Murphy
Publikováno v:
Biomater Sci
Autologous platelet-rich plasma (PRP) has gained popularity as a less invasive treatment for various musculoskeletal tissue injuries and conditions due to its favorable safety profile, minimal manipulation and cost-effectiveness. Although PRP treatme
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9459915d155241072219be1c379f42c5
https://doi.org/10.1039/d1bm01873f
https://doi.org/10.1039/d1bm01873f
Autor:
Michael Mullen, Alexander Goff, Jake Billings, Heidi Kloser, Charles Huard, John Mitchell, William Sealy Hambright, Sudheer Ravuri, Johnny Huard
Mesenchymal stem cells (MSCs) have long been viewed as a promising therapeutic for musculoskeletal repair. However, regulatory concerns including tumorgenicity, inconsistencies in preparation techniques, donor-to-donor variability, and the accumulati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::450b2e8d8e103472ff86bb9e9a5081c5
https://doi.org/10.1101/2022.11.15.516580
https://doi.org/10.1101/2022.11.15.516580
Autor:
Chi-Yi Lin, Xueqin Gao, Xiaodong Mu, Wanqun Chen, William S. Hambright, Ying Tang, Sudheer Ravuri, Polina Matre, Johnny Huard, Yan Cui, Ling Zhong, Bing Wang, Aiping Lu
Publikováno v:
Aging (Albany NY)
Duchenne Muscular Dystrophy (DMD) patients often suffer from both muscle wasting and osteoporosis. Our previous studies have revealed reduced regeneration potential in skeletal muscle and bone, concomitant with ectopic calcification of soft tissues i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bea0b6b517d2c17192b2fea2c03a14a0
https://doi.org/10.18632/aging.202413
https://doi.org/10.18632/aging.202413
Autor:
Xueqin Gao, Mintai P. Hwang, Nathaniel Wright, Aiping Lu, Joseph J. Ruzbarsky, Matthieu Huard, Haizi Cheng, Michael Mullen, Sudheer Ravuri, Bing Wang, Yadong Wang, Johnny Huard
Publikováno v:
Biomaterials
Nonunion following bone fracture and segmental bone defects are challenging clinical conditions. To combat this clinical dilemma, development of new bone tissue engineering therapies using biocompatible materials to deliver bone growth factors is des
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ab7c56d6936ba9934186f271c98a69c
https://doi.org/10.1016/j.biomaterials.2022.121708
https://doi.org/10.1016/j.biomaterials.2022.121708
Autor:
Marc J. Philippon, Hajime Utsunomiya, Dandan Zhu, Sudheer Ravuri, Alex C. Scibetta, Xueqin Gao, Catherine A. Logan, Walter R. Lowe, Mika Talwar, Joseph J. Ruzbarsky, Justin W. Arner, Johnny Huard
Publikováno v:
The American journal of sports medicine. 49(9)
Background: A previous publication demonstrated that the oral intake of losartan promoted microfracture-mediated hyaline-like cartilage repair in osteochondral defects of a rabbit knee model. However, an intra-articular (IA) injection of losartan may
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b166b02b5f26b54b17cdcbf12886ee1
https://pubmed.ncbi.nlm.nih.gov/34259597
https://pubmed.ncbi.nlm.nih.gov/34259597
Autor:
Xueqin Gao, Hajime Utsunomiya, Alex Scibetta, Sudheer Ravuri, Joseph Ruzbarsky, Camille Talwar, Justin Arner, Walter Lowe, Marc Philippon, Johnny Huard, Catherine Logan
Publikováno v:
Orthopaedic Journal of Sports Medicine
Objectives: 1. To determine the dosage and beneficial effects of intra-articular injection of losartan on microfracture-mediated cartilage repair and normal cartilage homeostasis. Methods: Rabbits were divided into 5 groups (n=6):a microfracture grou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00a8d7206f9b74a5c9a8320a0dc8b17f
http://europepmc.org/articles/PMC8327027
http://europepmc.org/articles/PMC8327027
Autor:
Johnny Huard, Ingrid K. Stake, Marc J. Philippon, Yoichi Murata, William S. Hambright, Naomasa Fukase, Sudheer Ravuri
Publikováno v:
Muscle Cell and Tissue-Novel Molecular Targets and Current Advances ISBN: 9781839686504
Aging affects bones, cartilage, muscles, and other connective tissue in the musculoskeletal system, leading to numerous age-related pathologies including osteoporosis, osteoarthritis, and sarcopenia. Understanding healthy aging may therefore open new
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::995dd1fb9f141b6ee1366dc5ae73e927
http://www.intechopen.com/articles/show/title/interventional-strategies-to-delay-aging-related-dysfunctions-of-the-musculoskeletal-system
http://www.intechopen.com/articles/show/title/interventional-strategies-to-delay-aging-related-dysfunctions-of-the-musculoskeletal-system