Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Sudheendra Hebbar Subramanyam"'
Autor:
Sudheendra Hebbar Subramanyam, Judit Turyne Hriczko, Angeliki Pappas, Angela Schippers, Nobert Wagner, Kim Ohl, Klaus Tenbrock
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-10 (2023)
Abstract Tofactinib is a JAK inhibitor approved for ulcerative colitis in humans. Despite of its’ proven effectiveness in humans, mechanistic data are scarce on the effectiveness of Tofactinib in experimental colitis in mice. We induced experimenta
Externí odkaz:
https://doaj.org/article/fd2696ae3047486a812ed569421d260d
Autor:
Angeliki Pappa, Julia Mührer, Patricia Gast, Sudheendra Hebbar Subramanyam, Kim Ohl, Moritz Muschaweck, Norbert Wagner, Tobias Wenzl, Klaus Tenbrock
Publikováno v:
Frontiers in Pediatrics, Vol 11 (2023)
ObjectivesCD4+ memory T cells facilitate long-termed adaptive immune responses while NK cells are predominately rapid effector cells with significant functions for both intestinal homeostasis and inflammation. We wanted to study both populations in h
Externí odkaz:
https://doaj.org/article/0ecec80e5d8b41a2b33158460a5caf7a
NRF2/Itaconate Axis Regulates Metabolism and Inflammatory Properties of T Cells in Children with JIA
Autor:
Anandhi Rajendiran, Sudheendra Hebbar Subramanyam, Patricia Klemm, Vera Jankowski, Jorg van Loosdregt, Bas Vastert, Kristina Vollbach, Norbert Wagner, Klaus Tenbrock, Kim Ohl
Publikováno v:
Antioxidants, Vol 11, Iss 12, p 2426 (2022)
Background: CD4+ T cells critically contribute to the initiation and perturbation of inflammation. When CD4+ T cells enter inflamed tissues, they adapt to hypoxia and oxidative stress conditions, and to a reduction in nutrients. We aimed to investiga
Externí odkaz:
https://doaj.org/article/7f77d089c8ce4a6695ab41a6071926f5
Autor:
Ling Xu, Lian Liu, Danlin Yao, Xiangbo Zeng, Yikai Zhang, Jing Lai, Jun Zhong, Xianfeng Zha, Runhui Zheng, Yuhong Lu, Minming Li, Zhenyi Jin, Sudheendra Hebbar Subramanyam, Shaohua Chen, Xin Huang, Yangqiu Li
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
Despite the great success of immune-checkpoint inhibitor (ICI) treatment for multiple cancers, evidence for the clinical use of ICIs in acute myeloid leukemia (AML) remains inadequate. Further exploration of the causes of immune evasion in the bone m
Externí odkaz:
https://doaj.org/article/0530309469c6485484285932f806bf03
Publikováno v:
Biological Chemistry. 402:1591-1596
The cAMP responsive element modulator (CREM) is a transcriptional regulator of different effector cytokines in CD4+ T cells including IL-2, IL-17, IL-21 but also IL-4 and IL-13 and thus an important determinant of central T helper cell functions. Our
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5858dd81154241a9152e155f37185ea4
https://doi.org/10.1515/hsz-2021-0249
https://doi.org/10.1515/hsz-2021-0249
Publikováno v:
Biological chemistryReferences. 402(12)
The cAMP responsive element modulator (CREM) is a transcriptional regulator of different effector cytokines in CD4
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::90ca1dad4173b01fd1bba307521f2266
https://pubmed.ncbi.nlm.nih.gov/34448385
https://pubmed.ncbi.nlm.nih.gov/34448385
Autor:
Dulce Cordeiro dos Santos, Jozef Vanden Broeck, Heleen Verlinden, Niels Wynant, Sudheendra Hebbar Subramanyam
Publikováno v:
Journal of Insect Physiology. 75:20-29
In this article, we identify and characterise the miRNA machinery components Drosha, Dicer-1 and Argonaute-1 of the desert locust. By means of phylogenetic analyses, we reveal important insights in the evolutionary context of these components. Our da
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9708c55555516604c54bc98072279de
https://doi.org/10.1016/j.jinsphys.2015.02.010
https://doi.org/10.1016/j.jinsphys.2015.02.010