Zobrazeno 1 - 10
of 392
pro vyhledávání: '"Sudhansu K. Dey"'
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-9 (2021)
Duncan et al. use a mass spectrometry imaging method to assess the localization and concentration of prostaglandins (PGs) in mouse tissues during pregnancy. This study brings new biological insights into the spatial evaluation of PGs in tissues, whic
Externí odkaz:
https://doaj.org/article/d0f035c37ed64c0983f6d3022ece020f
Autor:
Paul D. Piehowski, Ying Zhu, Lisa M. Bramer, Kelly G. Stratton, Rui Zhao, Daniel J. Orton, Ronald J. Moore, Jia Yuan, Hugh D. Mitchell, Yuqian Gao, Bobbie-Jo M. Webb-Robertson, Sudhansu K. Dey, Ryan T. Kelly, Kristin E. Burnum-Johnson
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-12 (2020)
Imaging mass spectrometry is a powerful emerging tool for mapping the spatial distribution of biomolecules across tissue surfaces. Here the authors showcase an automated technology for deep proteome imaging that utilizes ultrasensitive microfluidics
Externí odkaz:
https://doaj.org/article/e3b5a3a1d7b147dd83097e22370e56dc
Autor:
Jia Yuan, Shizu Aikawa, Wenbo Deng, Amanda Bartos, Gerd Walz, Florian Grahammer, Tobias B. Huber, Xiaofei Sun, Sudhansu K. Dey
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-10 (2019)
The scaffold protein Scribble (Scrib) has roles in PCP and tight junction formation. Here the authors show that during embryo implantation in mouse, Scrib is needed to form the avascular primary decidual zone by transforming stromal cells into an epi
Externí odkaz:
https://doaj.org/article/f219965601f64831b23b1f79def5b60b
Autor:
Alice H. Hsu, Michelle A. Lum, Kang-Sup Shim, Peter J. Frederick, Carl D. Morrison, Baojiang Chen, Subodh M. Lele, Yuri M. Sheinin, Takiko Daikoku, Sudhansu K. Dey, Gustavo Leone, Adrian R. Black, Jennifer D. Black
Publikováno v:
Cell Reports, Vol 24, Iss 3, Pp 655-669 (2018)
Summary: Protein kinase C (PKC) isozymes are commonly recognized as oncoproteins based on their activation by tumor-promoting phorbol esters. However, accumulating evidence indicates that PKCs can be inhibitory in some cancers, with recent findings p
Externí odkaz:
https://doaj.org/article/70af1efa537b465a82f8857a0e61398f
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-1 (2021)
Externí odkaz:
https://doaj.org/article/6a85703102ce48a4a9bc6cf567eb03b7
Endothelial Cells in the Decidual Bed Are Potential Therapeutic Targets for Preterm Birth Prevention
Autor:
Wenbo Deng, Jia Yuan, Jeeyeon Cha, Xiaofei Sun, Amanda Bartos, Hideo Yagita, Yasushi Hirota, Sudhansu K. Dey
Publikováno v:
Cell Reports, Vol 27, Iss 6, Pp 1755-1768.e4 (2019)
Summary: Preterm birth (PTB) is a syndrome with many origins. Among them, infection or inflammation are major risk factors for PTB; however, local defense mechanisms to mount anti-inflammatory responses against inflammation-induced PTB are poorly und
Externí odkaz:
https://doaj.org/article/bb44f8f6bb0d414191cc18762d19c2b3
Publikováno v:
Cell Reports, Vol 11, Iss 3, Pp 358-365 (2015)
During implantation, uterine luminal epithelial (LE) cells first interact with the blastocyst trophectoderm. Within 30 hr after the initiation of attachment, LE cells surrounding the blastocyst in the implantation chamber (crypt) disappear, allowing
Externí odkaz:
https://doaj.org/article/f10b7911a6284ee88b59063192adaa91
Autor:
Jeeyeon Cha, Amanda Bartos, Craig Park, Xiaofei Sun, Yingju Li, Sang-Wook Cha, Rieko Ajima, Hsin-Yi Henry Ho, Terry P. Yamaguchi, Sudhansu K. Dey
Publikováno v:
Cell Reports, Vol 8, Iss 2, Pp 382-392 (2014)
Embryo homing and implantation occur within a crypt (implantation chamber) at the antimesometrial (AM) pole along the uterus. The mechanism by which this is achieved is not known. Here, we show that villi-like epithelial projections from the main ute
Externí odkaz:
https://doaj.org/article/14bfc18ed32c4ffd9246a11e469215d3
Autor:
Kristin E. Burnum, Dale S. Cornett, Satu M. Puolitaival, Stephen B. Milne, David S. Myers, Susanne Tranguch, H. Alex Brown, Sudhansu K. Dey, Richard M. Caprioli
Publikováno v:
Journal of Lipid Research, Vol 50, Iss 11, Pp 2290-2298 (2009)
Molecular events involved in successful embryo implantation are not well understood. In this study, we used MALDI imaging mass spectrometry (IMS) technologies to characterize the spatial and temporal distribution of phospholipid species associated wi
Externí odkaz:
https://doaj.org/article/a9c1f45fd61d47fb9a3f85c330912923
Autor:
Beverly J. Tong, Jian Tan, Lovella Tajeda, Sanjoy K. Das, Julia A. Chapman, Raymond N. DuBois, Sudhansu K. Dey
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 2, Iss 6, Pp 483-490 (2000)
Epidemiological studies indicate that nonsteroidal anti-inflammatory drugs (NSAIDs) significantly reduce the risk and mortality from colorectal cancer, in part by inhibiting prostaglandin (PG) synthesis. Cyclooxygenase (COX), the rate-limiting enzyme
Externí odkaz:
https://doaj.org/article/9bad4bcef3e34a00823ce07920434856