Zobrazeno 1 - 10
of 149
pro vyhledávání: '"Sudhanshu P, Raikwar"'
Autor:
Faisal A. Alzahrani, Yasir M. Riza, Thamir M. Eid, Reema Almotairi, Lea Scherschinski, Jessica Contreras, Muhammed Nadeem, Sylvia E. Perez, Sudhanshu P. Raikwar, Ruchira M. Jha, Mark C. Preul, Andrew F. Ducruet, Michael T. Lawton, Kanchan Bhatia, Naseem Akhter, Saif Ahmad
Publikováno v:
Cells, Vol 13, Iss 8, p 670 (2024)
Neurodegenerative diseases, such as Alzheimer’s disease (AD), Parkinson’s disease (PD), amyotrophic lateral sclerosis (ALS), Huntington’s disease (HD), stroke, and aneurysms, are characterized by the abnormal accumulation and aggregation of dis
Externí odkaz:
https://doaj.org/article/47c15f5dfd5d4f6fa070862599279e02
Autor:
Duraisamy Kempuraj, Mohammad Ejaz Ahmed, Govindhasamy Pushpavathi Selvakumar, Ramasamy Thangavel, Sudhanshu P. Raikwar, Smita A. Zaheer, Shankar S. Iyer, Casey Burton, Donald James, Asgar Zaheer
Publikováno v:
Mediators of Inflammation, Vol 2020 (2020)
Traumatic brain injury (TBI) is one of the major health problems worldwide that causes death or permanent disability through primary and secondary damages in the brain. TBI causes primary brain damage and activates glial cells and immune and inflamma
Externí odkaz:
https://doaj.org/article/4cb671a6f59742f0b29426dde0a9bec7
Autor:
Suneel Gupta, Michael K. Fink, Duraisamy Kempuraj, Nishant R. Sinha, Lynn M. Martin, Landon M. Keele, Prashant R. Sinha, Elizabeth A. Giuliano, Nathan P. Hesemann, Sudhanshu P. Raikwar, Shyam S. Chaurasia, Rajiv R. Mohan
Publikováno v:
Mol Ther
Previously we found that inhibitor of differentiation 3 (Id3) gene, a transcriptional repressor, efficiently inhibits corneal keratocyte differentiation to myofibroblasts in vitro. This study evaluated the potential of adeno-associated virus 5 (AAV5)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08fa00a2da419839ce0b9e5d9a40fb7a
https://doi.org/10.1016/j.ymthe.2022.06.018
https://doi.org/10.1016/j.ymthe.2022.06.018
Autor:
Duraisamy Kempuraj, Shireen Mentor, Ramasamy Thangavel, Mohammad E. Ahmed, Govindhasamy Pushpavathi Selvakumar, Sudhanshu P. Raikwar, Iuliia Dubova, Smita Zaheer, Shankar S. Iyer, Asgar Zaheer
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 13 (2019)
Mast cell activation plays an important role in stress-mediated disease pathogenesis. Chronic stress cause or exacerbate aging and age-dependent neurodegenerative diseases. The severity of inflammatory diseases is worsened by the stress. Mast cell ac
Externí odkaz:
https://doaj.org/article/47a3aa91d7b045919e13565e7aaaa4ab
Autor:
Duraisamy Kempuraj, Govindhasamy P. Selvakumar, Ramasamy Thangavel, Mohammad E. Ahmed, Smita Zaheer, Sudhanshu P. Raikwar, Shankar S. Iyer, Sachin M. Bhagavan, Swathi Beladakere-Ramaswamy, Asgar Zaheer
Publikováno v:
Frontiers in Neuroscience, Vol 11 (2017)
Mast cells are localized throughout the body and mediate allergic, immune, and inflammatory reactions. They are heterogeneous, tissue-resident, long-lived, and granulated cells. Mast cells increase their numbers in specific site in the body by prolif
Externí odkaz:
https://doaj.org/article/6439ff2046784dac99bf8271e1b0a755
Autor:
Joshua S Catapano, Ruchira M. Jha, J. Marc Simard, Anupama Rani, Sandra Mihaljevic, Shashvat M. Desai, Volodymyr Gerzanich, Sudhanshu P. Raikwar, Amanda M. Casabella
Publikováno v:
Expert Opinion on Therapeutic Targets. 25:917-938
INTRODUCTION Cerebral edema is a key contributor to death and disability in several forms of brain injury. Current treatment options are limited, reactive, and associated with significant morbidity. Targeted therapies are emerging based on a growing
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6545a1b62bf39376f3cad697ce927432
https://doi.org/10.1080/14728222.2021.2010045
https://doi.org/10.1080/14728222.2021.2010045
Autor:
Duraisamy Kempuraj, Ramasamy Thangavel, Govindhasamy P. Selvakumar, Smita Zaheer, Mohammad E. Ahmed, Sudhanshu P. Raikwar, Haris Zahoor, Daniyal Saeed, Prashant A. Natteru, Shankar Iyer, Asgar Zaheer
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 11 (2017)
Neuroinflammatory response is primarily a protective mechanism in the brain. However, excessive and chronic inflammatory responses can lead to deleterious effects involving immune cells, brain cells and signaling molecules. Neuroinflammation induces
Externí odkaz:
https://doaj.org/article/867524e3c7d14fab89a08e2f951b7e90
Autor:
Govindhasamy Pushpavathi Selvakumar, Raghav Govindarajan, Shankar S. Iyer, Mohammad Ejaz Ahmed, Duraisamy Kempuraj, Sudhanshu P. Raikwar, Asgar Zaheer, Smita Zaheer, Deepak D. Kempuraj, Ramasamy Thangavel, Premkumar Nattanmai Chandrasekaran
Publikováno v:
BioFactors
Neuroinflammation leads to neurodegeneration, cognitive defects, and neurodegenerative disorders. Neurotrauma/traumatic brain injury (TBI) can cause activation of glial cells, neurons, and neuroimmune cells in the brain to release neuroinflammatory m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c980bc5898d521ba124cf5f6a72b10d9
https://doi.org/10.1002/biof.1687
https://doi.org/10.1002/biof.1687
Autor:
Sudhanshu P. Raikwar, Ramasamy Thangavel, Kieran Bazley, Shankar S. Iyer, Casey Burton, Osaid Khan, Raghav Govindarajan, Duraisamy Kempuraj, Mohammad Ejaz Ahmed, Donald James, Smita Zaheer, Bret Bussinger, Kristopher Wu, Klaudia Kukulka, Govindhasamy Pushpavathi Selvakumar, Asgar Zaheer
Publikováno v:
Cell Mol Neurobiol
Neurotrauma especially traumatic brain injury (TBI) is the leading cause of death and disability worldwide. To improve upon the early diagnosis and develop precision-targeted therapies for TBI, it is critical to understand the underlying molecular me
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::488d7e28340f5a9b246c7274dbac522b
https://doi.org/10.1007/s10571-020-00937-9
https://doi.org/10.1007/s10571-020-00937-9
Autor:
Govindhasamy Pushpavathi Selvakumar, Duraisamy Kempuraj, Kieran Bazley, Casey Burton, Asgar Zaheer, Sudhanshu P. Raikwar, Smita Zaheer, Shankar S. Iyer, Kristopher Wu, Donald James, Asher Khan, Osaid Khan, Mohammad Ejaz Ahmed, Ramasamy Thangavel
Publikováno v:
Molecular Neurobiology. 57:4438-4450
Traumatic brain injury (TBI) induces inflammatory responses through microglial activation and polarization towards a more inflammatory state that contributes to the deleterious secondary brain injury. Glia maturation factor (GMF) is a pro-inflammator
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3237d432bb6feabf54030ec33b67e1f7
https://doi.org/10.1007/s12035-020-02040-y
https://doi.org/10.1007/s12035-020-02040-y