Zobrazeno 1 - 10
of 73
pro vyhledávání: '"Sudhakaran Prabakaran"'
Publikováno v:
Malaria Journal, Vol 20, Iss 1, Pp 1-19 (2021)
Abstract Background Plasmodium falciparum causes the deadliest form of malaria, which remains one of the most prevalent infectious diseases. Unfortunately, the only licensed vaccine showed limited protection and resistance to anti-malarial drug is in
Externí odkaz:
https://doaj.org/article/fcaf9fbcd1d14864a26795c4a26342f7
Autor:
Chaitanya Erady, Adam Boxall, Shraddha Puntambekar, N. Suhas Jagannathan, Ruchi Chauhan, David Chong, Narendra Meena, Apurv Kulkarni, Bhagyashri Kasabe, Kethaki Prathivadi Bhayankaram, Yagnesh Umrania, Adam Andreani, Jean Nel, Matthew T. Wayland, Cristina Pina, Kathryn S. Lilley, Sudhakaran Prabakaran
Publikováno v:
npj Genomic Medicine, Vol 6, Iss 1, Pp 1-17 (2021)
Abstract Uncharacterized and unannotated open-reading frames, which we refer to as novel open reading frames (nORFs), may sometimes encode peptides that remain unexplored for novel therapeutic opportunities. To our knowledge, no systematic identifica
Externí odkaz:
https://doaj.org/article/410f193223914d33badf65ab4ce92412
Autor:
Shraddha Puntambekar, Rachel Newhouse, Jaime San Miguel Navas, Ruchi Chauhan, Grégoire Vernaz, Thomas Willis, Matthew T. Wayland, Yagnesh Umrania, Eric A. Miska, Sudhakaran Prabakaran
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-18 (2020)
Abstract Novel open reading frames (nORFs) with coding potential may arise from noncoding DNA. Not much is known about their emergence, functional role, fixation in a population or contribution to adaptive radiation. Cichlids fishes exhibit extensive
Externí odkaz:
https://doaj.org/article/d7a75993196c48729509b1ea6dea1a13
Autor:
Stephen Cole, Sudhakaran Prabakaran
Publikováno v:
iScience, Vol 23, Iss 8, Pp 101321- (2020)
Summary: Phosphorylation sites often have key regulatory functions and are central to many cellular signaling pathways, so mutations that modify them have the potential to contribute to pathological states such as cancer. Although many classifiers ex
Externí odkaz:
https://doaj.org/article/199b5ca69fbd4ff5ae6ef7795a463897
Autor:
Ana Filipa Domingues, Rashmi Kulkarni, George Giotopoulos, Shikha Gupta, Laura Vinnenberg, Liliana Arede, Elena Foerner, Mitra Khalili, Rita Romano Adao, Ayona Johns, Shengjiang Tan, Keti Zeka, Brian J Huntly, Sudhakaran Prabakaran, Cristina Pina
Publikováno v:
eLife, Vol 9 (2020)
Acute Myeloid Leukemia (AML) is an aggressive hematological malignancy with abnormal progenitor self-renewal and defective white blood cell differentiation. Its pathogenesis comprises subversion of transcriptional regulation, through mutation and by
Externí odkaz:
https://doaj.org/article/7e6a3304b0f24a67ac18c5d424b673f5
Autor:
Shraddha Puntambekar, Rachel Newhouse, Jaime San-Miguel, Ruchi Chauhan, Grégoire Vernaz, Thomas Willis, Matthew T. Wayland, Yagnesh Umrania, Eric A. Miska, Sudhakaran Prabakaran
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-1 (2021)
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
Externí odkaz:
https://doaj.org/article/4be8f2f7ae734982b0035be665817e0f
Autor:
Shikha Gupta, Oliver M. Dovey, Ana Filipa Domingues, Oliwia W. Cyran, Caitlin M. Cash, George Giotopoulos, Justyna Rak, Jonathan Cooper, Malgorzata Gozdecka, Liza Dijkhuis, Ryan J. Asby, Noor Al-Jabery, Victor Hernandez-Hernandez, Sudhakaran Prabakaran, Brian J. Huntly, George S. Vassiliou, Cristina Pina
Publikováno v:
Science advances. 8(31)
Data and materials availability: All data needed to evaluate the conclusions in the paper are present in the paper and/or the Supplementary Materials. scRNA-seq and bulk RNA-seq data were deposited in ArrayExpress with accession number E-MTAB-10853 a
Autor:
Chaitanya Erady, Krishna Amin, Temiloluwa O. A. E. Onilogbo, Jakub Tomasik, Rebekah Jukes-Jones, Yagnesh Umrania, Sabine Bahn, Sudhakaran Prabakaran
Funder: Ms. Chaitanya Erady was funded by Dr Manmohan Singh scholarship
Funder: Dr. Jakub Tomasik was funded by the Stanley Medical Research Institute (grant number: 07R-1888).
Funder: Prof. Sabine Bahn was funded by the Stanley Medical Res
Funder: Dr. Jakub Tomasik was funded by the Stanley Medical Research Institute (grant number: 07R-1888).
Funder: Prof. Sabine Bahn was funded by the Stanley Medical Res
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a187a5ee0e0baf090c89f0e25eefca07
Autor:
George S. Vassiliou, Oliver M. Dovey, Justyna Rak, Victor Hernandez-Hernandez, Sudhakaran Prabakaran, George Giotopoulos, Brian J. P. Huntly, Oliwia W. Cyran, Malgorzata Gozdecka, Jonathan D. Cooper, Ryan Asby, Cristina Pina, Ana Filipa Domingues, Caitlin M. Cash, Shikha Gupta, Noor Al-Jabery
Transcriptional variability facilitates stochastic cell diversification and can in turn underpin adaptation to stress or injury. We hypothesize that it may analogously facilitate progression of pre-malignancy to cancer. To investigate this, we initia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::06d8b3a2c6d6cedec942e1d2be47d29d
https://doi.org/10.1101/2021.10.18.464824
https://doi.org/10.1101/2021.10.18.464824
Autor:
Eric A. Miska, Thomas Willis, Sudhakaran Prabakaran, Matthew T. Wayland, Rachel Newhouse, Ruchi Chauhan, Grégoire Vernaz, Yagnesh Umrania, Shraddha Puntambekar, Jaime San-Miguel
Publikováno v:
Scientific Reports
Scientific Reports, Vol 11, Iss 1, Pp 1-1 (2021)
Scientific Reports, Vol 11, Iss 1, Pp 1-1 (2021)
Novel open reading frames (nORFs) with coding potential may arise from noncoding DNA. Not much is known about their emergence, functional role, fixation in a population or contribution to adaptive radiation. Cichlids fishes exhibit extensive phenotyp