Zobrazeno 1 - 10
of 48
pro vyhledávání: '"Sudhakar Veeranki"'
Autor:
Santosh K Sanganalmath, Shubham Dubey, Sudhakar Veeranki, Keerthy Narisetty, Prasanna Krishnamurthy
Publikováno v:
Cardiovascular Diabetology, Vol 22, Iss 1, Pp 1-22 (2023)
Abstract Diabetes mellitus is one of the prime risk factors for cardiovascular complications and is linked with high morbidity and mortality. Diabetic cardiomyopathy (DCM) often manifests as reduced cardiac contractility, myocardial fibrosis, diastol
Externí odkaz:
https://doaj.org/article/d40861dab903410eabe7c53c9d587c6b
Publikováno v:
PLoS ONE, Vol 6, Iss 5, p e19532 (2011)
Glucose restriction in cells increases the AMP/ATP ratio (energetic stress), which activates the AMPK/p53 pathway. Depending upon the energetic stress levels, cells undergo either autophagy or cell death. Given that the activated p53 induces the expr
Externí odkaz:
https://doaj.org/article/350b9e45f0f64414a6a3476330ede661
Publikováno v:
PLoS ONE, Vol 6, Iss 10, p e27040 (2011)
Type-I interferons (IFNs) are used to treat certain inflammatory diseases. Moreover, activation of type-I IFN-signaling in immune cells inhibits the production of proinflammatory cytokines and activation of inflammasomes. However, the molecular mecha
Externí odkaz:
https://doaj.org/article/5ac4a9d27fd240d1925042a5d2693cc2
Autor:
Ming C. Gong, Douglas A. Andres, Mihir Shah, Nemat Ali, Brooke M. Ahern, Andrea Sebastian, Julian E. Stelzer, Jiayang Li, Jonathan Satin, Wen Su, Sudhakar Veeranki, Bryana M. Levitan
Publikováno v:
J Biol Chem
Existing therapies to improve heart function target β-adrenergic receptor (β-AR) signaling and Ca(2+) handling and often lead to adverse outcomes. This underscores an unmet need for positive inotropes that improve heart function without any adverse
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ff2d87fa6796bab81be2b7418c39d22
https://doi.org/10.1074/jbc.ra119.008782
https://doi.org/10.1074/jbc.ra119.008782
Publikováno v:
Canadian Journal of Physiology and Pharmacology. 95:239-246
Although hyperhomocysteinemia (HHcy) is an independent risk factor for cardiovascular diseases (CVD), there is a debate on whether HHcy is a risk factor or just a biomarker. Interestingly, homocysteine lowering strategies in humans had very little ef
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::53b1e19aeb25c46886a258fdf75d3092
https://doi.org/10.1139/cjpp-2015-0568
https://doi.org/10.1139/cjpp-2015-0568
Autor:
Daheng He, Lyndsay E.A. Young, Tara R. Hawkinson, Chi Wang, Jonathan Satin, Sudhakar Veeranki, Bryana M. Levitan, Ramon C. Sun, Douglas A. Andres
Publikováno v:
J Biol Chem
MS-based metabolomics methods are powerful techniques to map the complex and interconnected metabolic pathways of the heart; however, normalization of metabolite abundance to sample input in heart tissues remains a technical challenge. Herein, we des
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::beaacaf55179351cd9a53f087cfd7fc2
https://pubmed.ncbi.nlm.nih.gov/31980460
https://pubmed.ncbi.nlm.nih.gov/31980460
Autor:
Jonathan Satin, Nemat Ali, Julian E. Stelzer, Doug Andres, Andrea Sebastian, Mihir Shah, Sudhakar Veeranki, Jiayang Li, Bryana M. Levitan, Brooke M. Ahern
Publikováno v:
Circulation Research. 125
The L-type Ca 2+ channel current (I Ca,L ) provides trigger Ca 2+ to contribute to cardiac contraction. Rad GTPase associates with the L-type Ca 2+ channel (LTCC) and serves as an endogenous inhibitor of LTCC activity. Overexpression of Rad blocks I
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::305196ceb0e41f88a6cddb554594a012
https://doi.org/10.1161/res.125.suppl_1.807
https://doi.org/10.1161/res.125.suppl_1.807
Autor:
Naira Metreveli, Sathnur Pushpakumar, Srikanth Givvimani, Suresh C. Tyagi, Sudhakar Veeranki, Sourav Kundu
Publikováno v:
Journal of Molecular and Cellular Cardiology. 92:163-173
Aims Although the cardiovascular benefits of exercise are well known, exercise induced effects and mechanisms in prevention of cardiomyopathy are less clear during obesity associated type-2 diabetes. The current study assessed the impact of moderate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b5017fc84705a20c6075f260d43971e
https://doi.org/10.1016/j.yjmcc.2016.01.023
https://doi.org/10.1016/j.yjmcc.2016.01.023
Publikováno v:
Annals of the New York Academy of Sciences. 1363:138-154
Despite great strides in understanding the atherogenesis process, the mechanisms are not entirely known. In addition to diet, cigarette smoking, genetic predisposition, and hypertension, hyperhomocysteinemia (HHcy), an accumulation of the noncoding s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::27fef40620060fd6cbc43e7db6ba4920
https://doi.org/10.1111/nyas.13009
https://doi.org/10.1111/nyas.13009
Autor:
David Scott, Sudhakar Veeranki
Publikováno v:
The FASEB Journal. 34:1-1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a42a40272ff46f1f8514925aad3175f6
https://doi.org/10.1096/fasebj.2020.34.s1.01977
https://doi.org/10.1096/fasebj.2020.34.s1.01977