Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Sudhakar, Jinka"'
Autor:
Sujan Kumar Mondal, Mohammed Tanveer Ahmed, Sudhakar Jinka, Sampa Sarkar, Ravi Shukla, Rajkumar Banerjee
Publikováno v:
Molecular Pharmaceutics.
Publikováno v:
Chemistry – An Asian Journal. 18
Autor:
Sujan Kumar, Mondal, Sudhakar, Jinka, Gajji, Shankar, Ragampeta, Srinivas, Rajkumar, Banerjee
Publikováno v:
Chemistry, an Asian journal.
Paclitaxel (PTX) is a widely used chemotherapeutic agent in the clinic. However, its clinical benefit is limited due to its low water solubility, off-target toxicity, and for being a multidrug-resistant (MDR) substrate. To overcome these limitations
Autor:
Sudhakar Jinka, Bhowmira Rathore, Kathyayani Sridharan, Hari Krishna Reddy Rachamalla, Yousuf, Rajkumar Banerjee, Madhan Mohan Chandra Sekhar Jaggarapu
Publikováno v:
Molecular Pharmaceutics. 18:1208-1228
Hydrocortisone, a natural glucocorticoid secreted by adrenal and extra-adrenal tissues, locally governs the transcription of genes involved in inflammation, immune response, metabolism, and energy homeostasis via binding to its cognate glucocorticoid
Autor:
Madan Mohan Chandra Sekhar Jaggarapu, Hari Krishna Reddy Rachamalla, Rajkumar Banerjee, Kathyayani Sridharan, Shruti S. Deshpande, Sunil Misra, Sujan Kumar Mondal, Kalpana Javaji, Vishnu Sravan Bollu, Sudhakar Jinka
Publikováno v:
Nanotoxicology. 13:1161-1175
Cationic lipids are well-known excipients for nanometric liposomal gene delivery systems. However, because of the suspected, collateral toxicity in normal cells, the use of cationic lipids for the treatment of human tumor is largely limited. Recently
Autor:
Bonda Rama Rao, Chitta Ranjan Patra, Arabinda Chaudhuri, Sudhakar Jinka, Suresh Kumar Gulla, Sara Khalid, Narendra Varma Nimmu, Gopikrishna Moku
Publikováno v:
Biomaterials Science. 7:773-788
The clinical success of dendritic cell (DC)-based genetic immunization remains critically dependent on the availability of effective and safe nano-carriers for targeting antigen-encoded DNA vaccines to DCs, the most potent antigen-presenting cells in
Autor:
Ushasri Chilakamarthi, Devulapally Koteshwar, Narra Vamsi Krishna, Kathyayani Sridharan, Sudhakar Jinka, Lingamallu Giribabu, Narayana Nagesh
Publikováno v:
Biochemistry. 57:6514-6527
Porphyrins are well-known anticancer agents because of their high binding affinity for G-quadruplex DNA and excellent photophysical properties. Several studies carried out using TMPyP4 established it as an efficient chemotherapeutic and a photodynami
Autor:
Madan Mohan Chandra Sekhar Jaggarapu, Kathyayani Sridharan, Tithi Bhattacharyya, Venu Yakati, Rajkumar Banerjee, Hari Krishna Reddy Rachamalla, Sudhakar Jinka
Publikováno v:
Biomedical materials (Bristol, England). 16(2)
High mortality rate in colon cancer patients is often attributed to late diagnosis. To overcome the conventional chemotherapy associated challenges, chemotherapeutic drugs (single or combination) or genetic drugs are often delivered using ligand-modi
Autor:
Ajaz Ahmad, Rajkumar Banerjee, Krishnendu Pal, Sujan Kumar Mondal, Khalid M. Alkharfy, Shamit K. Dutta, Swetha Nelli, Sudhakar Jinka, Enfeng Wang, Debabrata Mukhopadhyay
Publikováno v:
Molecular Pharmaceutics. 13:2507-2523
Many cancers including the late stage ones become drug-resistant and undergo epithelial-to-mesenchymal transition (EMT). These lead to enhanced invasion, migration, and metastasis toward manifesting its aggressiveness and malignancy. One of the key h
Publikováno v:
Bioorganic Chemistry. 98:103719
Stilbene-based compounds are largely described for their antioxidant activity. But their use as anticancer chemotherapeutics is hampered by poor pharmacokinetic properties and non-selectivity towards cancer and non-cancer potency. To overcome these d