Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Sudha Bhagwati"'
Autor:
Suriya P. Singh, Divya Rai, Alka Raj Pandey, Mohammad Imran Siddiqi, Alisha Ansari, Rabi Sankar Bhatta, Anjali Mishra, Ashish Kumar Tripathi, Naibedya Chattopadhyay, Ritu Trivedi, Anirban Sardar, Koneni V. Sashidhara, Sudha Bhagwati
Publikováno v:
Journal of Medicinal Chemistry. 64:12487-12505
The molecular hybridization concept led us to design a series of galloyl conjugates of flavanones that have potent osteoblast differentiation ability in vitro and promote bone formation in vivo. An array of in vitro studies, especially gene expressio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b9213af6cc29ca4ede7e8ea228202f0
https://doi.org/10.1021/acs.jmedchem.1c00112
https://doi.org/10.1021/acs.jmedchem.1c00112
Autor:
Sudha Bhagwati, Mohammad Imran Siddiqi
Publikováno v:
Journal of biomolecular structuredynamics. 40(10)
Renin enzyme plays an essential role in the Renin-Angiotensin System (RAS), and it is involved in the pathogenesis of hypertension and several other cardiovascular diseases (CVDs). Inhibition of renin is an effective way to intervene with the pathoge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad75189d0ffda067608cb4baab870bff
https://pubmed.ncbi.nlm.nih.gov/33336624
https://pubmed.ncbi.nlm.nih.gov/33336624
Publikováno v:
European journal of pharmacology. 899
Cyclic nucleotide phosphodiesterases (PDEs) are ubiquitously expressed enzymes that hydrolyze phosphodiester bond in the second messenger molecules including cAMP and cGMP. A wide range of drugs blocks one or more PDEs thereby preventing the inactiva
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::963f5e4649126e98757ae3668dc9c323
https://pubmed.ncbi.nlm.nih.gov/33711307
https://pubmed.ncbi.nlm.nih.gov/33711307
Publikováno v:
European journal of pharmacology. 886
Chronic alcoholism (CA) decreases bone mass and increases the risk of hip fracture. Alcohol and its main metabolite, acetaldehyde impairs osteoblastogenesis by increasing oxidative stress. Aldehyde dehydrogenase (ALDH) is the rate-limiting enzyme in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c91cbe384ddd8772cff07f34e951ffc
https://pubmed.ncbi.nlm.nih.gov/32896553
https://pubmed.ncbi.nlm.nih.gov/32896553
Publikováno v:
Journal of molecular graphicsmodelling. 96
Cathepsin S (CatS) is one of the cysteinyl cathepsins widely studied for its clinical significance and found to be a promising therapeutic target for several diseases; to name a few is arthritis, allergic inflammation, cancer, diabetes, obesity, and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b72c3cabe1c9582a0bb9b7c7a2a53e2a
https://pubmed.ncbi.nlm.nih.gov/31881466
https://pubmed.ncbi.nlm.nih.gov/31881466
Autor:
Akanksha Upadhyay, Mohd Imran Siddiqi, Pragati Kushwaha, Sudha Bhagwati, Sampa Gupta, Tanvi Baghel, Soobiya Fatima, Koneni V. Sashidhara, Aamir Nazir
Publikováno v:
Bioorganicmedicinal chemistry letters. 29(1)
A series of novel Benzofuran-tetrazole derivatives were successfully synthesised by integrating multicomponent Ugi-azide reaction with the molecular hybridization approach. Interestingly, a number of synthesized derivatives (5c, 5d, 5i, 5l, 5q and 5s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a15ae152bdba6cfbe6a4aebf821dddde
https://pubmed.ncbi.nlm.nih.gov/30455151
https://pubmed.ncbi.nlm.nih.gov/30455151
Autor:
Rajender Singh, Sudha Bhagwati
Publikováno v:
Male Infertility: Understanding, Causes and Treatment ISBN: 9789811040160
In a number of lower organisms and seasonal breeders, availability of food is a key determinant in shaping the time for reproduction and fertility. Therefore, food and nutrition strongly affect fertility, even in nonseasonal breeders. Eating a balanc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7e45634e4c784aaad9a8418e0c84d9a1
https://doi.org/10.1007/978-981-10-4017-7_20
https://doi.org/10.1007/978-981-10-4017-7_20
Autor:
Rajender Singh, Sudha Bhagwati
Publikováno v:
Male Infertility: Understanding, Causes and Treatment ISBN: 9789811040160
Male infertility is a disorder with an undefined etiology in about half of the cases. It has devastating effects on personal and social life of a couple. In the past few years, the modern medical sciences have prospered a lot; however, in spite of gr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::682d0b690a4d2de88f04ae8a4ff67daa
https://doi.org/10.1007/978-981-10-4017-7_21
https://doi.org/10.1007/978-981-10-4017-7_21