Zobrazeno 1 - 10
of 99
pro vyhledávání: '"Sudha, Visvanathan"'
Autor:
Luc Francis, Daniel McCluskey, Clarisse Ganier, Treasa Jiang, Xinyi Du-Harpur, Jeyrroy Gabriel, Pawan Dhami, Yogesh Kamra, Sudha Visvanathan, Jonathan N. Barker, Catherine H. Smith, Francesca Capon, Satveer K. Mahil
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract Biologic therapies targeting the IL-23/IL-17 axis have transformed the treatment of psoriasis. However, the early mechanisms of action of these drugs remain poorly understood. Here, we perform longitudinal single-cell RNA-sequencing in affec
Externí odkaz:
https://doaj.org/article/7ba2923c9a9945248d418768b1ba2572
Autor:
Alba Garrido-Trigo, Ana M. Corraliza, Marisol Veny, Isabella Dotti, Elisa Melón-Ardanaz, Aina Rill, Helena L. Crowell, Ángel Corbí, Victoria Gudiño, Miriam Esteller, Iris Álvarez-Teubel, Daniel Aguilar, M. Carme Masamunt, Emily Killingbeck, Youngmi Kim, Michael Leon, Sudha Visvanathan, Domenica Marchese, Ginevra Caratù, Albert Martin-Cardona, Maria Esteve, Ingrid Ordás, Julian Panés, Elena Ricart, Elisabetta Mereu, Holger Heyn, Azucena Salas
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-18 (2023)
Abstract Ulcerative colitis and Crohn’s disease are chronic inflammatory intestinal diseases with perplexing heterogeneity in disease manifestation and response to treatment. While the molecular basis for this heterogeneity remains uncharacterized,
Externí odkaz:
https://doaj.org/article/91914e5f5fdd496f894dce921d226bce
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Generalized pustular psoriasis (GPP) is a rare, chronic, inflammatory skin disorder characterized by recurrent flares associated with skin erythema, desquamation, and widespread superficial sterile pustules, which may be severe (“lakes of pus”).
Externí odkaz:
https://doaj.org/article/1ebaf70efb874a9e8f9a85113d0f2d54
Autor:
Alba Garrido-Trigo, Ana M. Corraliza, Marisol Veny, Isabella Dotti, Elisa Melón-Ardanaz, Aina Rill, Helena L. Crowell, Ángel Corbí, Victoria Gudiño, Miriam Esteller, Iris Álvarez-Teubel, Daniel Aguilar, M. Carme Masamunt, Emily Killingbeck, Youngmi Kim, Michael Leon, Sudha Visvanathan, Domenica Marchese, Ginevra Caratù, Albert Martin-Cardona, Maria Esteve, Ingrid Ordás, Julian Panés, Elena Ricart, Elisabetta Mereu, Holger Heyn, Azucena Salas
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-1 (2024)
Externí odkaz:
https://doaj.org/article/b3bab41a702941269b02108c15092e84
Autor:
Wu-lin Zuo, Mahboubeh R. Rostami, Shushila A. Shenoy, Michelle G. LeBlanc, Jacqueline Salit, Yael Strulovici-Barel, Sarah L. O’Beirne, Robert J. Kaner, Philip L. Leopold, Jason G. Mezey, Juergen Schymeinsky, Karsten Quast, Sudha Visvanathan, Jay S. Fine, Matthew J. Thomas, Ronald G. Crystal
Publikováno v:
Respiratory Research, Vol 21, Iss 1, Pp 1-11 (2020)
Abstract Background The human small airway epithelium (SAE) plays a central role in the early events in the pathogenesis of most inherited and acquired lung disorders. Little is known about the molecular phenotypes of the specific cell populations co
Externí odkaz:
https://doaj.org/article/af8f66ce0af64a4dbed6220fd72ca500
Autor:
Guoqing Wang, Howard H. Lou, Jacqueline Salit, Philip L. Leopold, Sharon Driscoll, Juergen Schymeinsky, Karsten Quast, Sudha Visvanathan, Jay S. Fine, Matthew J. Thomas, Ronald G. Crystal
Publikováno v:
Respiratory Research, Vol 20, Iss 1, Pp 1-14 (2019)
Abstract Background The pathology of chronic obstructive pulmonary disease (COPD), idiopathic pulmonary fibrosis (IPF) and most lung cancers involves the small airway epithelium (SAE), the single continuous layer of cells lining the airways ≥ 6th g
Externí odkaz:
https://doaj.org/article/82c6978c7ece4e0c99b57b46a05bef69
Autor:
Wu-Lin Zuo, Mahboubeh R Rostami, Michelle LeBlanc, Robert J Kaner, Sarah L O'Beirne, Jason G Mezey, Philip L Leopold, Karsten Quast, Sudha Visvanathan, Jay S Fine, Matthew J Thomas, Ronald G Crystal
Publikováno v:
PLoS ONE, Vol 15, Iss 9, p e0237529 (2020)
Idiopathic pulmonary fibrosis (IPF) is a progressive, chronic fibrotic lung disease with an irreversible decline of lung function. "Bronchiolization", characterized by ectopic appearance of airway epithelial cells in the alveolar regions, is one of t
Externí odkaz:
https://doaj.org/article/0145c5d89b5d45929b0413cd0eb395e9
Publikováno v:
PLoS ONE, Vol 15, Iss 11, p e0242863 (2020)
Pathophysiology of systemic sclerosis (SSc, Scleroderma), an autoimmune rheumatic disease, comprises of mechanisms that drive vasculopathy, inflammation and fibrosis. Understanding of the disease and associated clinical heterogeneity has advanced con
Externí odkaz:
https://doaj.org/article/64990983fb7e41878305a65643414865
Autor:
David R Jayne, Jürgen Steffgen, Juanita Romero‐Diaz, Ingeborg Bajema, Dimitrios T Boumpas, Kajohnsak Noppakun, Hirofumi Amano, Harold Michael Gomez, Bancha Satirapoj, Yingyos Avihingsanon, Ratana Chawanasuntorapoj, Magdalena Madero, Beata Naumnik, Rhona Recto, Nora Fagan, Ivette Revollo, Jing Wu, Sudha Visvanathan, Richard Furie
Publikováno v:
Arthritis & Rheumatology.
Autor:
Alba Garrido-Trigo, Ana M. Corraliza, Marisol Veny, Isabella Dotti, Elisa Melon-Ardanaz, Aina Rill, Helena L. Crowell, Ángel Corbí, Victoria Gudiño, Miriam Esteller, Iris Álvarez-Teubel, Daniel Aguilar, M Carme Masamunt, Emily Killingbeck, Youngmi Kim, Michael Leon, Sudha Visvanathan, Domenica Marchese, Ginevra Caratù, Albert Martin-Cardona, Maria Esteve, Julian Panés, Elena Ricart, Elisabetta Mereu, Holger Heyn, Azucena Salas
Ulcerative colitis (UC) and Crohn’s disease (CD) are chronic inflammatory intestinal diseases that show a perplexing heterogeneity in manifestations and response to treatment. The molecular basis for this heterogeneity remains uncharacterized. We a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ccd80da16af26ca6d99c6afb1e8d4885
https://doi.org/10.1101/2022.11.28.518139
https://doi.org/10.1101/2022.11.28.518139