Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Sudeepta Aggarwal"'
Autor:
Megan N Landis, Stacy R Smith, Gabriel Berstein, Gerald Fetterly, Pranab Ghosh, Gang Feng, Vivek Pradhan, Sudeepta Aggarwal, Christopher Banfield, Elena Peeva, Michael S Vincent, Jean S Beebe, Sanela Tarabar
Publikováno v:
British Journal of Dermatology.
Background Plaque psoriasis (PsO) is an inflammatory skin disease driven, in part, by the activation of Janus kinase (JAK) signalling pathways. Objectives To assess the efficacy and safety of multiple doses of topical brepocitinib, a tyrosine kinase
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4c050877b4031a6cf8082f8c53d27a09
https://doi.org/10.1093/bjd/ljad098
https://doi.org/10.1093/bjd/ljad098
Autor:
Albert M. Kim, Neeta B. Amin, Arthur Bergman, Roberto A. Calle, Theresa Tuthill, Kou Kou, Sudeepta Aggarwal, Naresh Aggarwal, Collin Crowley, Anthony Rinaldi, Santos Carvajal-Gonzalez, Veena Somayaji, Kendra K. Bence, Jessica Mancuso, Trenton T. Ross, Magalie Boucher, William P. Esler, Robert Dullea, Jeffrey A. Pfefferkorn, Małgorzata Inglot, Greg Tesz
Publikováno v:
Nature Medicine. 27:1836-1848
Alterations in lipid metabolism might contribute to the pathogenesis of non-alcoholic fatty liver disease (NAFLD). However, no pharmacological agents are currently approved in the United States or the European Union for the treatment of NAFLD. Two pa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6895fcce96fd1d7f12fcd3678e85c1ff
https://doi.org/10.1038/s41591-021-01489-1
https://doi.org/10.1038/s41591-021-01489-1
Autor:
Megan N. Landis, Mark Arya, Stacy Smith, Zoe Draelos, Lisa Usdan, Sanela Tarabar, Vivek Pradhan, Sudeepta Aggarwal, Christopher Banfield, Elena Peeva, Michael S. Vincent, Vanja Sikirica, Jason Xenakis, Jean S. Beebe
Publikováno v:
The British journal of dermatologyReferences. 187(6)
Background Atopic dermatitis (AD) is a prevalent inflammatory, pruritic skin disease. The Janus kinase (JAK) pathway is a treatment target. Objectives To assess the efficacy, safety and pharmacokinetics of topical cream brepocitinib, a small-molecule
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6cef62276a1c4d898f2ddd859b40f148
https://pubmed.ncbi.nlm.nih.gov/36199210
https://pubmed.ncbi.nlm.nih.gov/36199210
Autor:
Roberto Calle, Sudeepta Aggarwal, Jessica Mancuso, Arthur Bergman, Veena Somayaji, Trenton Ross, William Esler
Publikováno v:
Journal of Hepatology. 73:S455
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0b4a798b38c0bd00dcf06ca090fc5abe
https://doi.org/10.1016/s0168-8278(20)31392-1
https://doi.org/10.1016/s0168-8278(20)31392-1
Autor:
Mark R, Rigby, Linda A, DiMeglio, Marc S, Rendell, Eric I, Felner, Jean M, Dostou, Stephen E, Gitelman, Chetanbabu M, Patel, Kurt J, Griffin, Eva, Tsalikian, Peter A, Gottlieb, Carla J, Greenbaum, Nicole A, Sherry, Wayne V, Moore, Roshanak, Monzavi, Steven M, Willi, Philip, Raskin, Antoinette, Moran, William E, Russell, Ashley, Pinckney, Lynette, Keyes-Elstein, Michael, Howell, Sudeepta, Aggarwal, Noha, Lim, Deborah, Phippard, Gerald T, Nepom, James, McNamara, Mario R, Ehlers, Faith, Brendle
Publikováno v:
The lancet. Diabetes & endocrinology, vol 1, iss 4
Summary Background Type 1 diabetes results from autoimmune targeting of the pancreatic β cells, likely mediated by effector memory T (Tem) cells. CD2, a T cell surface protein highly expressed on Tem cells, is targeted by the fusion protein alefacep
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50d168c693ebbcc9b8ecbd65fa79f533
https://doi.org/10.1016/s2213-8587(13)70111-6
https://doi.org/10.1016/s2213-8587(13)70111-6
Autor:
Stephen E, Gitelman, Peter A, Gottlieb, Mark R, Rigby, Eric I, Felner, Steven M, Willi, Lynda K, Fisher, Antoinette, Moran, Michael, Gottschalk, Wayne V, Moore, Ashley, Pinckney, Lynette, Keyes-Elstein, Sudeepta, Aggarwal, Deborah, Phippard, Peter H, Sayre, Linna, Ding, Jeffrey A, Bluestone, Mario R, Ehlers, Betty, Flores
Publikováno v:
Gitelman, SE; Gottlieb, PA; Rigby, MR; Felner, EI; Willi, SM; Fisher, LK; et al.(2013). Antithymocyte globulin treatment for patients with recent-onset type 1 diabetes: 12-month results of a randomised, placebo-controlled, phase 2 trial. The Lancet Diabetes and Endocrinology, 1(4), 306-316. doi: 10.1016/S2213-8587(13)70065-2. UC San Francisco: Retrieved from: http://www.escholarship.org/uc/item/2sp5f6xx
Background: Type 1 diabetes results from T-cell-mediated destruction of β cells. Findings from preclinical studies and pilot clinical trials suggest that antithymocyte globulin (ATG) might be effective for reducing this autoimmune response. We asses
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::675987137597c23e018d0a31b475c9c7
https://doi.org/10.1016/s2213-8587(13)70065-2
https://doi.org/10.1016/s2213-8587(13)70065-2
Autor:
G. Jonah Rainey, Valentina Ciccarone, Linda Jin, Sudeepta Aggarwal, Ezio Bonvini, Yinhua Yang, Wenjun Zhang, Paul A. Moore, Steve Burke, Syd Johnson, Sunan Zhang, Leilei He, Maria Concetta Veri, Scott Koenig, Kalpana Shah, Ling Huang, Sergey Gorlatov, Tengfei Zhang, Hua Li
Publikováno v:
Blood. 117:4542-4551
We describe the application of a novel, bispecific antibody platform termed dual affinity retargeting (DART) to eradicate B-cell lymphoma through coengagement of the B cell–specific antigen CD19 and the TCR/CD3 complex on effector T cells. Comparis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::592341cafb9e92c114f5f999aab74a69
https://doi.org/10.1182/blood-2010-09-306449
https://doi.org/10.1182/blood-2010-09-306449
Autor:
Sudeepta Aggarwal, Brian Feild, Tao He, Deborah Mesmer, William Fitzhugh, Kim Rosenthal, Steven M. Ruben, Paul A. Moore, Jenny Heidbrink
Publikováno v:
Gynecologic Oncology. 115:430-437
Objective We have used mass-spectrometry (MS) based proteomics platform to identify cell surface proteins over-expressed on a cisplatin resistant derivative of an ovarian cancer cell line A2780. Methods Membrane associated glycoproteins from A2780 an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01ed9874015d93a6f2e383b72ed66322
https://doi.org/10.1016/j.ygyno.2009.08.031
https://doi.org/10.1016/j.ygyno.2009.08.031
Autor:
James Lee, Susan Guillet, Guohua Pan, Jessica Foster, Katrina Nicholes, Peter Schow, Miko Maruoka, Weiguang Mao, Dorothy French, Sudeepta Aggarwal, Austin L. Gurney, Philip Risser
Publikováno v:
The Journal of Immunology. 167:6559-6567
IL-17 is a proinflammatory cytokine, and its in vivo expression induces neutrophilia in mice. IL-17E is a recently described member of an emerging family of IL-17-related cytokines. IL-17E has been shown to bind IL-17Rh1, a protein distantly related
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb9dc3b0d435ff57245176e25acdb1aa
https://doi.org/10.4049/jimmunol.167.11.6559
https://doi.org/10.4049/jimmunol.167.11.6559
Autor:
Jeremy Stinson, Zemin Zhang, Austin L. Gurney, Sudeepta Aggarwal, Wei-Hsien Ho, William I. Wood, Audrey Goddard, Ming-Hong Xie, Jessica Foster
Publikováno v:
Journal of Biological Chemistry. 275:31335-31339
We report the identification of a novel human cytokine, distantly related to interleukin (IL)-10, which we term IL-22. IL-22 is produced by activated T cells. IL-22 is a ligand for CRF2-4, a member of the class II cytokine receptor family. No high af
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3e3da402a7c6d46bae150cc568d21b1
https://doi.org/10.1074/jbc.m005304200
https://doi.org/10.1074/jbc.m005304200