Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Sudeep Sabde"'
Autor:
Anand Tarage, Gopal Gole, Mandar Bhonde, Madhusudhan Reddy, Sharad Sharma, Harish Volam, Sudeep Sabde, Sanjeev Anant Kulkarni, Sadanand Mallurwar, Brahmam Sunkara, Ramesh Dattatraya Phadtare, Manoj Dandekar, Hemant Goyal, Samiron Phukan, Gayathri Sadasivam, Rupesh Kanhere, Maneesh Mehta, Nirmal Jana, Murthy Cheemala, Prashant Vidhate, Lal Dinchhana, Prashant B. Nigade, Bernstein Peter Robert, Prajakta Ahirrao, Rajan Goel, Aditya Naik, Vipul Pachpute, Sukanya Patra, Rajender Kumar Kamboj, Nilesh Mahajan, Kaustubh Tamane, Sneha Trivedi, M. K. Singh, Ajit Kumar Marisetti, Shankar Bhagwat, Mahip Verma, Atul Akarte, Dipak Lagad, Charudatt Samant, Venkata P. Palle, Vinod Patil, Anand Bokare, Dipak Modi, Chaitanya A. Kulkarni, Lakshmi Narasimham, Neetinkumar Reddy, Majid Bashir Sayyed, Sarita Koul, Shukla Manojkumar Ramprasad, Milind Gholve, Swati Tota, Vinod D. Chaudhari, Jayasagar Gundu, Manisha Shingare, Sachin J Mahangare, Shashikant Pawar
Publikováno v:
Journal of Medicinal Chemistry. 63:14700-14723
PI3Kδ inhibitors have been approved for B-cell malignancies like CLL, small lymphocytic lymphoma, and so forth. However, currently available PI3Kδ inhibitors are nonoptimal, showing weakness against at least one of the several important properties:
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c4614f9af4bf378b9f2f87f030837f97
https://doi.org/10.1021/acs.jmedchem.0c01264
https://doi.org/10.1021/acs.jmedchem.0c01264
Autor:
Vijay Kanoje, Dilip Pandey, Akshaya Wagh, Sukanya Patra, Ajit Kumar Marisetti, Madhusudhan Reddy, Charudatt Samant, Nilesh Mahajan, Milind Gholve, Sudeep Sabde, Sneha Trivedi, Trupti Bhankhede, Vinod Patil, Prashant Nigade, Dipak Modi, Maneesh Mehta, Prajakta Ahirrao, Swathi Tota, Bidyut Nanda, Shashikant Pawar, Anuradha Polawar, Kaustubh Tamane, Sandip Kuldharan, Gururaj Vishwase, Nirmal Jana, Sachin J. Mahangare, Prashant Vidhate, Dipak Lagad, Jayasagar Gundu, Samiron Phukan, Manojkumar Shukla, Lakshmi Narasimham, Kumar V.S. Nemmani, Mandar Bhonde, Sharad Sharma, Rajender K. Kamboj, Venkata P. Palle
Publikováno v:
European Journal of Pharmacology. 927:175054
PI3Kδ plays a critical role in adaptive immune cell activation and function. Suppression of PI3Kδ has been shown to counter excessive triggering of immune responses which has led to delineating the role of this isoform in the pathophysiology of aut
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7aa76af2abcce55ae46c64c0a261b565
https://doi.org/10.1016/j.ejphar.2022.175054
https://doi.org/10.1016/j.ejphar.2022.175054
Autor:
Manojkumar R, Shukla, Sukanya, Patra, Mahip, Verma, Gayathri, Sadasivam, Nirmal, Jana, Sachin J, Mahangare, Prashant, Vidhate, Dipak, Lagad, Anand, Tarage, Murthy, Cheemala, Chaitanya, Kulkarni, Shankar, Bhagwat, Vinod D, Chaudhari, Majid, Sayyed, Vipul, Pachpute, Ramesh, Phadtare, Gopal, Gole, Samiron, Phukan, Brahmam, Sunkara, Charudatt, Samant, Manisha, Shingare, Aditya, Naik, Sneha, Trivedi, Ajit Kumar, Marisetti, Madhusudhan, Reddy, Milind, Gholve, Nilesh, Mahajan, Sudeep, Sabde, Vinod, Patil, Dipak, Modi, Maneesh, Mehta, Prashant, Nigade, Kaustubh, Tamane, Swati, Tota, Hemant, Goyal, Harish, Volam, Shashikant, Pawar, Prajakta, Ahirrao, Lal, Dinchhana, Sadanand, Mallurwar, Atul, Akarte, Anand, Bokare, Rupesh, Kanhere, Neetinkumar, Reddy, Sarita, Koul, Manoj, Dandekar, Minakshi, Singh, Peter R, Bernstein, Lakshmi, Narasimham, Mandar, Bhonde, Jayasagar, Gundu, Rajan, Goel, Sanjeev, Kulkarni, Sharad, Sharma, Rajender Kumar, Kamboj, Venkata P, Palle
Publikováno v:
Journal of medicinal chemistry. 63(23)
PI3Kδ inhibitors have been approved for B-cell malignancies like CLL, small lymphocytic lymphoma, and so forth. However, currently available PI3Kδ inhibitors are nonoptimal, showing weakness against at least one of the several important properties:
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9740bbdfcab4b764d76303bebfd167f6
https://pubmed.ncbi.nlm.nih.gov/33297683
https://pubmed.ncbi.nlm.nih.gov/33297683
Autor:
Sudeep Sabde, Pritam N. Dube, Pravin Deshmukh, Yogesh Patil, Santosh N. Mokale, Bhupendra Yadav, Sameer I. Shaikh
Publikováno v:
Pharmaceutical Chemistry Journal. 49:125-131
A series of substituted imidazole-5-one derivatives containing aminopyrimidine were synthesized. The synthesized compounds were evaluated for their in vitro reverse transcriptase inhibitor (RTI) activity by using reverse transcriptase colorimetric as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::da921b991a459ccb694cd32a97428ddf
https://doi.org/10.1007/s11094-015-1235-7
https://doi.org/10.1007/s11094-015-1235-7
Autor:
Melissa R. Jacob, Nafees Ahmed, Kamlesh K. Bhutani, Babu L. Tekwani, Shabana Khan, Sudeep Sabde, Debashis Mitra, Ikhlas A. Khan, Inder Pal Singh, Keyur G. Brahmbhatt
Publikováno v:
Chemical Biology & Drug Design. 81:491-498
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c177161890711da524717ea98e44248f
https://doi.org/10.1111/cbdd.1427
https://doi.org/10.1111/cbdd.1427
Autor:
Sudeep Sabde, Inder Pal Singh, Debashis Mitra, Kamlesh K. Bhutani, Keyur G. Brahmbhatt, Nafees Ahmed
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 20:4416-4419
A series of β-carboline derivatives were synthesized by utilizing aromatization and chemoselective alkylation method recently reported from our laboratory. Synthesized derivatives were evaluated for anti-HIV activity in human CD4+ T cell line (CEM-G
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ddd6859f9e04db32f97a0ab71eee9881
https://doi.org/10.1016/j.bmcl.2010.06.052
https://doi.org/10.1016/j.bmcl.2010.06.052
Autor:
Sudeep Sabde, Nafees Ahmed, Inder Pal Singh, Keyur G. Brahmbhatt, Debashis Mitra, Kamlesh K. Bhutani
Publikováno v:
Bioorganic & Medicinal Chemistry. 18:2872-2879
Naturally occurring quinolone alkaloids, buchapine (1) and compound 2 were synthesized as reported in literature and evaluated for anti-HIV potential in human CD4+ T cell line CEM-GFP, infected with HIV-1(NL4.3) virus by p24 antigen capture ELISA ass
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca83ad61a360e299991bac6b67c4b050
https://doi.org/10.1016/j.bmc.2010.03.015
https://doi.org/10.1016/j.bmc.2010.03.015
Autor:
Sudeep Sabde, Inder Pal Singh, Debashis Mitra, Sandip B. Bharate, Siddheshwar K. Chauthe, Kamlesh K. Bhutani
Publikováno v:
Bioorganic & Medicinal Chemistry. 18:2029-2036
Plants are an important source of a variety of bioactive compounds with different modes of action. Anti-HIV agents from plant sources can be useful in developing novel therapies for inhibiting HIV infection. Based on the reported anti-HIV activity of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1de537089cc0c877ee4c7e1c4aabe5c0
https://doi.org/10.1016/j.bmc.2010.01.023
https://doi.org/10.1016/j.bmc.2010.01.023
Autor:
Melissa R. Jacob, Shabana I. Khan, Keyur G. Brahmbhatt, Nafees Ahmed, Sudeep Sabde, Debashis Mitra, Kamlesh K. Bhutani, Ikhlas A. Khan, Inder Pal Singh, Babu Lal Tekwani
Publikováno v:
Chemical biologydrug design. 81(4)
Fifty analogues of batzelladine K were synthesized and evaluated for in vitro antimalarial (Plasmodium falciparum), antileishmanial (Leishmania donovani), antimicrobial (panel of bacteria and fungi), antiviral (HIV-1) activities. Analogues 14h and 20
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe89188a45d843655fa83f7c3ef0310b
https://pubmed.ncbi.nlm.nih.gov/23534411
https://pubmed.ncbi.nlm.nih.gov/23534411
Autor:
Palakolanu S. Reddy, C. Bhaskar, K. Sarath Chandra, Debashis Mitra, Anand K. Kondapi, Sudeep Sabde
Publikováno v:
Biochimica et biophysica acta. 1834(4)
Early pregnancy associated protein-1 (Epap-1), a 90 kDa glycoprotein present in first trimester placental tissue, inhibits HIV-1 entry through interaction with HIV-1 gp120 at V3 and C5 regions. In the present study, we have identified the specific 32
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2cbf687e1fe3a16f996caf059f424ea8
https://pubmed.ncbi.nlm.nih.gov/23360764
https://pubmed.ncbi.nlm.nih.gov/23360764