Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Sudath Hapuarachchige"'
Autor:
Ioanna Liatsou, Betelhem Assefa, Wathsala Liyanage, Sharmane Surasinghe, Zora Nováková, Cyril Bařinka, Kathleen Gabrielson, Venu Raman, Dmitri Artemov, Sudath Hapuarachchige
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
Prostate cancer (PC) is an aggressive cancer that can progress rapidly and eventually become castrate-resistant prostate cancer (CRPC). Stage IV metastatic castrate-resistant prostate cancer (mCRPC) is an incurable late-stage cancer type with a low 5
Externí odkaz:
https://doaj.org/article/e55e46e0874d464dbbedcee553133c11
Autor:
Sudath Hapuarachchige, Dmitri Artemov
Publikováno v:
Frontiers in Oncology, Vol 10 (2020)
Theranostics are nano-size or molecular-level agents serving for both diagnosis and therapy. Structurally, they are drug delivery systems integrated with molecular or targeted imaging agents. Theranostics are becoming popular because they are targete
Externí odkaz:
https://doaj.org/article/f5f246ebc5484498add61b784c3d0caa
Autor:
Sudath Hapuarachchige, Yoshinori Kato, Ethel J Ngen, Barbara Smith, Michael Delannoy, Dmitri Artemov
Publikováno v:
PLoS ONE, Vol 11, Iss 5, p e0156294 (2016)
This paper reports the damaging effects of magnetic iron-oxide nanoparticles (MNP) on magnetically labeled cancer cells when subjected to oscillating gradients in a strong external magnetic field. Human breast cancer MDA-MB-231 cells were labeled wit
Externí odkaz:
https://doaj.org/article/d60ed7a6b27347fe9277a02aadbfdcdb
Publikováno v:
ACS Appl Nano Mater
Ultrasmall superparamagnetic iron oxide nanoparticles (uSPIOs) are attractive platforms for the development of smart contrast agents for magnetic resonance imaging (MRI). Oleic acid-capped uSPIOs are commercially available yet hydrophobic, hindering
Autor:
Xin Guo, Shawn E. Lupold, Colin T. Huang, Dmitri Artemov, Venu Raman, Martin G. Pomper, Cyril Bařinka, Sudath Hapuarachchige, Kathleen L. Gabrielson
Publikováno v:
Mol Pharm
Prostate cancer (PC) is a potentially high-risk disease and the most common cancer in American men. It is a leading cause of cancer-related deaths in men in the US, second only to lung and bronchus cancer. Advanced and metastatic PC is initially trea
Autor:
Xin Guo, Wojciech G. Lesniak, Ge Si, Kathleen L. Gabrielson, Colin T. Huang, Dmitri Artemov, Ronnie C. Mease, Sudath Hapuarachchige
Publikováno v:
Biomacromolecules
Pretargeted drug delivery has been explored for decades as a promising approach in cancer therapy. An image-guided pretargeting strategy significantly enhances the intrinsic advantages of this approach since imaging the pretargeting step can be used
Autor:
Jiefu Jin, Zhihang Chen, Marie-France Penet, Zaver M. Bhujwalla, Sudath Hapuarachchige, Samata Kakkad, Dmitri Artemov
Publikováno v:
Journal of Magnetic Resonance. 291:141-151
Most diseases, especially cancer, would significantly benefit from precision medicine where treatment is shaped for the individual. The concept of theragnostics or theranostics emerged around 2002 to describe the incorporation of diagnostic assays in
Autor:
Dmitri Artemov, Sudath Hapuarachchige
Publikováno v:
Topics in Magnetic Resonance Imaging. 25:205-213
Click chemistry provides fast, convenient, versatile, and reliable chemical reactions that take place between pairs of functional groups of small molecules that can be purified without chromatographic methods. Due to the fast kinetics and low or no e
Publikováno v:
Chemistry of Heterocyclic Compounds. 50:254-263
There is great potential for novel diagnostic and therapeutic agents that combine multiple imaging modalities. The combination of optical and radionuclide imaging systems is particularly promising for the improved management of cancer. We describe a
Autor:
Barbara S. Smith, Michael Delannoy, Ethel J. Ngen, Yoshinori Kato, Dmitri Artemov, Sudath Hapuarachchige
Publikováno v:
PLoS ONE
PLoS ONE, Vol 11, Iss 5, p e0156294 (2016)
PLoS ONE, Vol 11, Iss 5, p e0156294 (2016)
This paper reports the damaging effects of magnetic iron-oxide nanoparticles (MNP) on magnetically labeled cancer cells when subjected to oscillating gradients in a strong external magnetic field. Human breast cancer MDA-MB-231 cells were labeled wit