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pro vyhledávání: '"Sudarshan Singh Thapa"'
Autor:
Sudarshan Singh Thapa, Anne Grove
Publikováno v:
Antibiotics, Vol 8, Iss 4, p 160 (2019)
The emergence of multiple antibiotic resistant bacteria has pushed the available pool of antibiotics to the brink. Bacterial secondary metabolites have long been a valuable resource in the development of antibiotics, and the genus Burkholderia has re
Externí odkaz:
https://doaj.org/article/13a5795e9279454ebd010eff14f25450
Autor:
Sudarshan Singh Thapa, Anne Grove
Publikováno v:
Molecular microbiologyREFERENCES. 115(4)
One of the most commonly prescribed antibiotics against Burkholderia infections is co-trimoxazole, a cocktail of trimethoprim and sulfamethoxazole. Trimethoprim elicits an upregulation of the mal gene cluster, which encodes proteins involved in synth
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f046d055d8540a9afce6c0e3200b4f23
https://pubmed.ncbi.nlm.nih.gov/33053234
https://pubmed.ncbi.nlm.nih.gov/33053234
Autor:
Sudarshan Singh Thapa, Anne Grove
Publikováno v:
The FASEB Journal. 34:1-1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2531e3c303e4722d48f694602478f7c6
https://doi.org/10.1096/fasebj.2020.34.s1.09165
https://doi.org/10.1096/fasebj.2020.34.s1.09165
SUMMARY Species within the genus Burkholderia exhibit remarkable phenotypic diversity. Genomic plasticity, including genome reduction and horizontal gene transfer, has been correlated with virulence traits in several species. However, the conservatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3f7b3e63ffdf5e47582203da7781265
https://europepmc.org/articles/PMC6383443/
https://europepmc.org/articles/PMC6383443/
Autor:
Sudarshan Singh Thapa, Maheshi Dassanayake, Renesh Bedre, Anne Grove, Guannan Wang, Afsana Sabrin, Ashish Gupta
Publikováno v:
ACS chemical biology. 12(12)
Many bacteria encode biosynthetic proteins that produce a vast array of natural products. These compounds are often synthesized during host invasion as they function as virulence factors. In addition, such secondary metabolites have yielded numerous
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38ad5143e52516e8e2a03b5e5a134d21
https://pubmed.ncbi.nlm.nih.gov/29283242
https://pubmed.ncbi.nlm.nih.gov/29283242
Autor:
Anne Grove, Sudarshan Singh Thapa
Publikováno v:
Antibiotics
Antibiotics, Vol 8, Iss 4, p 160 (2019)
Antibiotics, Vol 8, Iss 4, p 160 (2019)
The emergence of multiple antibiotic resistant bacteria has pushed the available pool of antibiotics to the brink. Bacterial secondary metabolites have long been a valuable resource in the development of antibiotics, and the genus Burkholderia has re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d545a446426e673c445341eb336c15d
https://doi.org/10.3390/antibiotics8040160
https://doi.org/10.3390/antibiotics8040160
Autor:
Sudarshan Singh Thapa, Maheshi Dassanayake, Anne Grove, Ashish Gupta, Guannan Wang, Renesh Bedre, Afsana Sabrin
Publikováno v:
ACS Chemical Biology. 13:282-282
Many bacteria encode biosynthetic proteins that produce a vast array of natural products. These compounds are often synthesized during host invasion as they function as virulence factors. In addition, such secondary metabolites have yielded numerous
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8208a6f6321d31aec0b3d7dc5aa9abb
https://doi.org/10.1021/acschembio.7b01056
https://doi.org/10.1021/acschembio.7b01056