Zobrazeno 1 - 10
of 122
pro vyhledávání: '"Sudarshan Ramachandran"'
Autor:
Geoffrey Hackett, Amar Mann, Ahmad Haider, Karim S. Haider, Pieter Desnerck, Carola S. König, Richard C. Strange, Sudarshan Ramachandran
Publikováno v:
The World Journal of Men's Health, Vol 42, Iss 4, Pp 749-761 (2024)
Purpose: While testosterone therapy can improve the various pathologies associated with adult-onset testosterone deficiency (TD), Summary of Product Characteristics (SPC) of five testosterone preparations caution that treatment may be associated wi
Externí odkaz:
https://doaj.org/article/e5a878eab02448e1842bd55b5b696b26
Autor:
Sudarshan Ramachandran, Amro Maarouf, Karen Mitchell, Tony Avades, Peter Smith, Lee Boulton, Jennifer Kelly, Nitasha Vekaria, Elizabeth Hughes
Publikováno v:
Drugs in Context, Vol 13, Pp 1-11 (2024)
Background: Bempedoic acid, an adenosine triphosphate citrate lyase inhibitor, was introduced to UK practice via a pre-reimbursement access scheme for adults with primary hypercholesterolaemia or mixed dyslipidaemia who are at high risk of cardiovasc
Externí odkaz:
https://doaj.org/article/9f6774c74e7c4137841acfb2c7b85d94
Autor:
Mark Livingston, Adrian Heald, Geoffrey Hackett, Harishnath Ramachandran, Sudarshan Ramachandran
Publikováno v:
The Aging Male, Vol 27, Iss 1 (2024)
Background Studies assessing variability of serum testosterone levels associated with seasonal environmental factors have been contradictory.Design We assessed associations between the seasons and changes (δ) in seasonality indices and male serum to
Externí odkaz:
https://doaj.org/article/4bb24ad1936946498e77f31d6c9d12d5
Autor:
Karim Sultan Haider, Michael Zitzmann, Pravinath Ramachandran, Carola S. König, Geoffrey Hackett, Ahmad Haider, Farid Saad, Pieter Desnerck, Richard Strange, Amar Mann, Sudarshan Ramachandran
Publikováno v:
The Aging Male, Vol 27, Iss 1 (2024)
Objective We evaluated change (Δ) in AMSS in men with adult-onset testosterone deficiency (TD) on/not on testosterone undecanoate (TU) by analysing a registry of men with adult-onset TD.Methods Analyses were performed using non-parametric statistics
Externí odkaz:
https://doaj.org/article/eab0be84aa034bc2a103ae5037a73467
Autor:
Geoffrey Hackett, Michael Kirby, Rowland W. Rees, T. Hugh Jones, Asif Muneer, Mark Livingston, Nick Ossei-Gerning, Janine David, Jeff Foster, Philip A. Kalra, Sudarshan Ramachandran
Publikováno v:
The World Journal of Men's Health, Vol 41, Iss 3, Pp 508-537 (2023)
Testosterone deficiency (TD) is an increasingly common problem with significant health implications, but its diagnosis and management can be challenging. A multi-disciplinary panel from BSSM reviewed the available literature on TD and provide evide
Externí odkaz:
https://doaj.org/article/ab57d77e43964fcfba17e4eea83123cd
Autor:
Carola S. König, Amar Mann, Rob McFarlane, John Marriott, Malcolm Price, Sudarshan Ramachandran
Publikováno v:
Biomedicines, Vol 11, Iss 12, p 3208 (2023)
We believe that there is sufficient evidence from basic science, longitudinal cohort studies and randomised controlled trials which validates the low-density lipoprotein cholesterol (LDL-C) or lipid hypothesis. It is important that we can communicate
Externí odkaz:
https://doaj.org/article/3550ae4f3e1b4616a5b01b91414b23fa
Autor:
Jemma Hudson, MSc, Moira Cruickshank, PhD, Richard Quinton, MD, Lorna Aucott, PhD, Magaly Aceves-Martins, PhD, Katie Gillies, PhD, Shalender Bhasin, ProfMB BS, Peter J Snyder, ProfMD, Susan S Ellenberg, ProfPhD, Mathis Grossmann, ProfPhD, Thomas G Travison, PhD, Emily J Gianatti, PhD, Yvonne T van der Schouw, ProfPhD, Marielle H Emmelot-Vonk, ProfPhD, Erik J Giltay, PhD, Geoff Hackett, FRCPI, Sudarshan Ramachandran, PhD, Johan Svartberg, ProfPhD, Kerry L Hildreth, MD, Kristina Groti Antonic, PhD, Gerald B Brock, ProfMD, J Lisa Tenover, ProfMD, Hui Meng Tan, FRCS, Christopher Ho Chee Kong, FRCS, Wei Shen Tan, PhD, Leonard S Marks, ProfMD, Richard J Ross, ProfMD, Robert S Schwartz, ProfMD, Paul Manson, BA Hons, Stephen Roberts, PhD, Marianne Skovsager Andersen, ProfDmSci, Line Velling Magnussen, PhD, Rodolfo Hernández, PhD, Nick Oliver, ProfFRCP, Frederick Wu, ProfMD, Waljit S Dhillo, ProfPhD, Siladitya Bhattacharya, ProfMD, Miriam Brazzelli, PhD, Channa N Jayasena, PhD
Publikováno v:
The Lancet. Healthy Longevity, Vol 3, Iss 6, Pp e381-e393 (2022)
Summary: Background: Testosterone is the standard treatment for male hypogonadism, but there is uncertainty about its cardiovascular safety due to inconsistent findings. We aimed to provide the most extensive individual participant dataset (IPD) of t
Externí odkaz:
https://doaj.org/article/70b4dbf3d7d14292b6edc7c0fd36828c
Publikováno v:
The World Journal of Men's Health, Vol 38, Iss 1, Pp 68-77 (2020)
UKPurpose: To describe the 4-year metabolic follow-up results from the BLAST study.Materials and Methods: Baseline hemoglobin A1c (HbA1c), weight, and waist circumference (WC) data were recorded in 185 men recruited for the BLAST randomised controlle
Externí odkaz:
https://doaj.org/article/c9519d98f97349e3b94a4296b2871810
Autor:
Tim Reynolds, Peter Carey, Jacob George, Gerasimos Konidaris, Deepa Narayanan, Sudarshan Ramachandran, Luke Saunders, Adie Viljoen, Gordon Ferns
Publikováno v:
Drugs - Real World Outcomes, Vol 6, Iss 4, Pp 205-213 (2019)
Abstract Background Alirocumab is a fully human monoclonal antibody to proprotein convertase subtilisin/kexin type 9 (PCSK9) and has been previously shown, in the phase III ODYSSEY clinical trial program, to provide significant lowering of low-densit
Externí odkaz:
https://doaj.org/article/b5a41f369992465e9ecd7add54203f9c
Publikováno v:
European Cardiology Review, Vol 14, Iss 2, Pp 103-110 (2019)
The development of a subnormal level of testosterone (T) is not universal in ageing men, with 75% of men retaining normal levels. However, a substantial number of men do develop T deficiency (TD), with many of them carrying a portfolio of cardiovascu
Externí odkaz:
https://doaj.org/article/0302bc902c7c44b3b4b8a7c5c4cb5708