Výsledky vyhledávání

Akademický článek

The impact of astrocytic NF-κB on healthy and Alzheimer’s disease brains

Autor: Tee Jong Huat, Judith Camats-Perna, Estella A. Newcombe, Tessa Onraet, Daniel Campbell, Josiah T. Sucic, Alessandra Martini, Stefânia Forner, Mehdi Mirzaei, Wayne Poon, Frank M. LaFerla, Rodrigo Medeiros

Publikováno v: Scientific Reports, Vol 14, Iss 1, Pp 1-14 (2024)

Abstract Astrocytes play a role in healthy cognitive function and Alzheimer’s disease (AD). The transcriptional factor nuclear factor-κB (NF-κB) drives astrocyte diversity, but the mechanisms are not fully understood. By combining studies in huma

Externí odkaz: https://doaj.org/article/d45850a975f546e0b5129c724d247f07

Zobrazit plný text záznamu

Plný text ve formátu HTML

Akademický článek

A transporter’s doom or destiny: SLC6A1 in health and disease, novel molecular targets and emerging therapeutic prospects

Autor: Nikita Shah, Ameya S. Kasture, Florian P. Fischer, Harald H. Sitte, Thomas Hummel, Sonja Sucic

Publikováno v: Frontiers in Molecular Neuroscience, Vol 17 (2024)

As the first member of the solute carrier 6 (SLC6) protein family, the γ-aminobutyric acid (GABA) transporter 1 (GAT1, SLC6A1), plays a pivotal role in the uptake of GABA from the synaptic cleft into neurons and astrocytes. This process facilitates

Externí odkaz: https://doaj.org/article/32a4d9eccf1a45ecadbc7b915b884790

Zobrazit plný text záznamu

Akademický článek

Misregulation of mitochondrial 6mA promotes the propagation of mutant mtDNA and causes aging in C. elegans

Autor: Hahn, Anne, Hung, Grace Ching Ching, Ahier, Arnaud, Dai, Chuan-Yang, Kirmes, Ina, Forde, Brian M., Campbell, Daniel, Lee, Rachel Shin Yie, Sucic, Josiah, Onraet, Tessa, Zuryn, Steven

Publikováno v: In Cell Metabolism 3 December 2024 36(12):2528-2541

Zobrazit plný text záznamu

Akademický článek

Review of EU projects with a focus on environmental quality: Innovation, eco-innovation, and circular-economy elements

Autor: Hojnik, Jana, Ruzzier, Mitja, Konečnik Ruzzier, Maja, Sučić, Boris, Soltwisch, Brandon, Rus, Matej

Publikováno v: In International Journal of Innovation Studies March 2024 8(1):1-12

Zobrazit plný text záznamu

Akademický článek

Adaptive Thresholding for Sparse Image Reconstruction

Autor: I. Volaric, V. Sucic

Publikováno v: Telfor Journal, Vol 15, Iss 1, Pp 8-13 (2023)

The performance of the class of sparse reconstruction algorithms which is based on the iterative thresholding is highly dependent on a selection of the appropriate threshold value, controlling a trade-off between the algorithm execution time and the

Externí odkaz: https://doaj.org/article/7b14a5fedfab4b2b80d4153c8f7059b5

Zobrazit plný text záznamu