Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Suchitra Matsukura"'
Autor:
Suchitra Matsukura, Yuji Nakamura, Kiyotaka Hoshiai, Takashi Hayashi, Tadashi Koga, Ai Goto, Koki Chiba, Nur Jaharat Lubna, Mihoko Hagiwara-Nagasawa, Hiroko Izumi-Nakaseko, Kentaro Ando, Atsuhiko T. Naito, Atsushi Sugiyama
Publikováno v:
Journal of Pharmacological Sciences, Vol 136, Iss 4, Pp 234-241 (2018)
Effects of moxifloxacin on QTc as well as proarrhythmic surrogate markers including J-Tpeakc, Tpeak-Tend and short-term variability (STV) of repolarization were examined by using both standard E14 time-based evaluation and exposure-response modeling.
Externí odkaz:
https://doaj.org/article/4b072f6c9a1e436b85b3f154ccdacb31
Autor:
Suchitra Matsukura, Yuji Nakamura, Xin Cao, Takeshi Wada, Hiroko Izumi-Nakaseko, Kentaro Ando, Hiroshi Yamazaki, Atsushi Sugiyama
Publikováno v:
Journal of Pharmacological Sciences, Vol 133, Iss 2, Pp 103-109 (2017)
We pharmacologically characterized microminipigs as an in vivo experimental model by assessing cardiovascular effects of pilsicainide, verapamil and E-4031, which can preferentially inhibit cardiac Na+, Ca2+ and K+ channels, respectively. Intravenous
Externí odkaz:
https://doaj.org/article/2b67043284f54d62bdc345c0b7f0d62e
Autor:
Atsushi Sugiyama, Kentaro Ando, Suchitra Matsukura, Takeshi Wada, Hiroko Izumi-Nakaseko, Xin Cao, Hiroshi Yamazaki, Yuji Nakamura
Publikováno v:
Journal of Pharmacological Sciences, Vol 133, Iss 2, Pp 103-109 (2017)
We pharmacologically characterized microminipigs as an in vivo experimental model by assessing cardiovascular effects of pilsicainide, verapamil and E-4031, which can preferentially inhibit cardiac Na+, Ca2+ and K+ channels, respectively. Intravenous
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad484b585b8d22c616fba004d9c42363
http://www.sciencedirect.com/science/article/pii/S1347861317300178
http://www.sciencedirect.com/science/article/pii/S1347861317300178
Autor:
Yuji Nakamura, Suchitra Matsukura, Takeshi Wada, Hiroko Izumi-Nakaseko, Kentaro Ando, Xin Cao, Atsushi Sugiyama
Publikováno v:
Cardiovascular Toxicology. 17:157-162
Anti-atrial fibrillatory and proarrhythmic potentials of amiodarone were simultaneously analyzed by using the halothane-anesthetized beagle dogs (n = 4) in order to begin to prepare standard protocol for clarifying both efficacy and adverse effects o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4b9f5c63f37aa5d56e182fbb6773bd4
https://doi.org/10.1007/s12012-016-9369-8
https://doi.org/10.1007/s12012-016-9369-8
Autor:
Xin Cao, Kentaro Ando, Hiroshi Ohara, Suchitra Matsukura, Atsushi Sugiyama, Yoshikiyo Akasaka, Hiroko Izumi-Nakaseko, Yuji Nakamura, Takeshi Wada
Publikováno v:
Journal of Veterinary Medical Science. 78:873-876
A 14 month-old intact microminipig, weighing 8 kg, showed ST-segment elevation in A-B lead electrocardiogram during cardiac catheterization followed by ventricular tachycardia, which degenerated into ventricular fibrillation. Although a direct curren
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cee0ccbeb042a425f66949d5b1fadff6
https://doi.org/10.1292/jvms.15-0426
https://doi.org/10.1292/jvms.15-0426
Autor:
Takashi Hayashi, Suchitra Matsukura, Kiyotaka Hoshiai, Koki Chiba, Yuji Nakamura, Nur Jaharat Lubna, Tadashi Koga, Ai Goto, Hiroko Izumi-Nakaseko, Mihoko Hagiwara-Nagasawa, Kentaro Ando, Atsuhiko T. Naito, Atsushi Sugiyama
Publikováno v:
Journal of Pharmacological Sciences, Vol 136, Iss 4, Pp 234-241 (2018)
Effects of moxifloxacin on QTc as well as proarrhythmic surrogate markers including J-Tpeakc, Tpeak-Tend and short-term variability (STV) of repolarization were examined by using both standard E14 time-based evaluation and exposure-response modeling.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::266654883c042245a518731c513c1b65
https://pubmed.ncbi.nlm.nih.gov/29627227
https://pubmed.ncbi.nlm.nih.gov/29627227
Autor:
Yuji Nakamura, Hiroko Izumi-Nakaseko, Kentaro Ando, Xin Cao, Takeshi Wada, Atsushi Sugiyama, Suchitra Matsukura, Atsuhiko T. Naito
Publikováno v:
Basicclinical pharmacologytoxicology. 121(6)
Using moxifloxacin and terfenadine, which are known to induce benign and malignant QT interval prolongation, respectively, we analysed whether halothane-anaesthetized microminipigs are an appropriate model for assessing the risk of drug-induced long
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec1db02e62ee84921516895f9b867738
https://pubmed.ncbi.nlm.nih.gov/28654209
https://pubmed.ncbi.nlm.nih.gov/28654209
Autor:
Suchitra MATSUKURA, Yuji NAKAMURA, Hiroshi OHARA, Xin CAO, Takeshi WADA, Hiroko IZUMI-NAKASEKO, Kentaro ANDO, Yoshikiyo AKASAKA, Atsushi SUGIYAMA
Publikováno v:
Journal of Veterinary Medical Science; May2016, Vol. 78 Issue 5, p873-876, 4p