Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Suchitra Barge"'
Autor:
Miguel Pinilla-Vera, Zeyu Xiong, Yutong Zhao, Jing Zhao, Michael P Donahoe, Suchitra Barge, William T Horne, Jay K Kolls, Bryan J McVerry, Anastasiya Birukova, Robert M Tighe, W Michael Foster, John Hollingsworth, Anuradha Ray, Rama Mallampalli, Prabir Ray, Janet S Lee
Publikováno v:
PLoS ONE, Vol 11, Iss 7, p e0159329 (2016)
Despite recent advances in understanding macrophage activation, little is known regarding how human alveolar macrophages in health calibrate its transcriptional response to canonical TLR4 activation. In this study, we examined the full spectrum of LP
Externí odkaz:
https://doaj.org/article/ef02527a842b489e8b337410d2604e08
Publikováno v:
Haematologica, Vol 100, Iss 10 (2015)
Externí odkaz:
https://doaj.org/article/f879f7620fb649cfa92e595b1687b992
Autor:
Enrico M. Novelli, Gregory J. Kato, Mariana E. Hildesheim, Suchitra Barge, Michael P. Meyer, Jay Lozier, Andrea Cortese Hassett, Margaret V. Ragni, Jeffrey S. Isenberg, Mark T. Gladwin
Publikováno v:
Haematologica, Vol 98, Iss 11 (2013)
Externí odkaz:
https://doaj.org/article/feac139f831d48cdae114cf2b6364075
Autor:
Shilpa Jain, Maria G Kapetanaki, Nalini Raghavachari, Kimberly Woodhouse, Guoying Yu, Suchitra Barge, Claudia Coronnello, Panayiotis V Benos, Gregory J Kato, Naftali Kaminski, Mark T Gladwin
Publikováno v:
PLoS ONE, Vol 8, Iss 4, p e60932 (2013)
BACKGROUND:Increased platelet activation in sickle cell disease (SCD) contributes to a state of hypercoagulability and confers a risk of thromboembolic complications. The role for post-transcriptional regulation of the platelet transcriptome by micro
Externí odkaz:
https://doaj.org/article/c4ebd653265b4a60be6e3f1477435a33
Autor:
Yingze Zhang, Julie A. Reisz, Sarah Gehrke, Jessica B. Badlam, Chenell Donadee, Michael G. Risbano, Angelo D'Alessandro, Tamir Kanias, Shilpa Jain, Mark T. Gladwin, Suchitra Barge, Darrell J. Triulzi, Keisha Alexander
Publikováno v:
Blood Advances. 3:884-896
Cold storage of blood for 5 to 6 weeks has been shown to impair endothelial function after transfusion and has been associated with measures of end-organ dysfunction. Although the products of hemolysis, such as cell-free plasma hemoglobin, arginase,
Publikováno v:
Haematologica. 100:e390-e393
Vaso-occlusive crisis is the primary reason for emergency medical care sought by Sickle Cell Disease (SCD) patients.[1][1] In vivo imaging in transgenic SCD mice has identified molecular events that may promote vaso-occlusion.[2][2]–[4][3] However,
Autor:
Enrico M. Novelli, Nayra Cardenes, Sruti Shiva, Catherine Corey, Shilpa Jain, Lisa Geary, Suchitra Barge, Sergey Zharikov
Publikováno v:
Blood. 123:2864-2872
Bioenergetic dysfunction, although central to the pathogenesis of numerous diseases, remains uncharacterized in many patient populations because of the invasiveness of obtaining tissue for mitochondrial studies. Although platelets are an accessible s
Autor:
Bryan J. McVerry, Robert M. Tighe, Suchitra Barge, W. Michael Foster, Anastasiya Birukova, Yutong Zhao, William Horne, Rama K. Mallampalli, Prabir Ray, Anuradha Ray, Miguel Pinilla-Vera, John W. Hollingsworth, Jay K. Kolls, Janet S. Lee, Jing Zhao, Zeyu Xiong, Michael P. Donahoe
Publikováno v:
PLoS ONE, Vol 11, Iss 7, p e0159329 (2016)
PLoS ONE
PLoS ONE
Despite recent advances in understanding macrophage activation, little is known regarding how human alveolar macrophages in health calibrate its transcriptional response to canonical TLR4 activation. In this study, we examined the full spectrum of LP
Autor:
Gregory J. Kato, Margaret V. Ragni, Michael P. Meyer, Victor R. Gordeuk, Yingze Zhang, Andrea L. Cortese Hassett, Mark T. Gladwin, Mariana Hildesheim, Jeffrey S. Isenberg, Suchitra Barge, Enrico M. Novelli, Mehdi Nouraie
Publikováno v:
American Journal of Hematology. 87:326-330
Platelets are activated in sickle cell disease (SCD), and particularly during vaso-occlusive episodes (VOE). Thrombospondin-1 (TSP1), a major secretory product of activated platelets, is increased in the circulation in VOE and binds to sickle red blo
Autor:
Shilpa Jain, Jessica B. Badlam, Mark T. Gladwin, Darrel Triulzi, Daniel B. Kim-Shapiro, Michael G. Risbano, Tamir Kanias, Suchitra Barge, Chenell Donadee, Andrea Belanger
A major abnormality that characterizes the red cell "storage lesion" is increased hemolysis and reduced red cell lifespan after infusion. Low levels of intravascular hemolysis after transfusion of aged stored red cells disrupt nitric oxide (NO) bioav
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e9c030053ba1d1e7aa4edab928f52bb
https://europepmc.org/articles/PMC4731619/
https://europepmc.org/articles/PMC4731619/