Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Sucheta Sircar"'
Publikováno v:
Virology. 270:173-179
Adenoviruses encode a cysteine protease, adenain, required for uncoating and virion maturation. Adenain activity is regulated by an 11-amino-acid peptide cofactor thiol-bonded distal to the active site. Structural and experimental data suggest that t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::343ea9e3d5760e3ce9f67b832e9c440e
https://doi.org/10.1006/viro.2000.0253
https://doi.org/10.1006/viro.2000.0253
Publikováno v:
Virology. 268:141-146
The serpins SCCA1 and SCCA2 are highly expressed in the epithelium of the conducting airways, a common site of infection by group C adenoviruses, such as human adenovirus type 2 (Ad2). Based on the common location we examined a possible interaction b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9cf63b664c7d29575e02aaee38a76d6
https://doi.org/10.1006/viro.1999.0139
https://doi.org/10.1006/viro.1999.0139
Publikováno v:
Antiviral Research. 40:45-51
Adenoviruses encode a cysteine protease (AVP) which carries out highly specific cleavages on at least seven viral proteins and two cellular proteins. Virus infectivity is dependent on this function. The three-dimensional positions of the amino acids
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f723b9759b99c700924efe3d1e2d5d83
https://doi.org/10.1016/s0166-3542(98)00040-0
https://doi.org/10.1016/s0166-3542(98)00040-0
Publikováno v:
Virology. 191:187-192
We have previously described a revertant cell line which expresses a dominant tumor suppressor phenotype to E1 but not to heterologous oncogenes such as c-myc, N-ras, or polyoma middle t (Sircar et al. (1988) Oncogene 3, 725–728). DNA tumor virus o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::708f90c088387d82181ad27cf692ec7b
https://doi.org/10.1016/0042-6822(92)90180-w
https://doi.org/10.1016/0042-6822(92)90180-w
Publikováno v:
Antiviral research. 58(2)
Green tea catechins have been reported to inhibit proteases involved in cancer metastasis and infection by influenza virus and HIV. To date there are no effective anti-adenoviral therapies. Consequently, we studied the effect of green tea catechins,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c1e32c7fa4e5e06849e2e8c91c3758dd
https://pubmed.ncbi.nlm.nih.gov/12742577
https://pubmed.ncbi.nlm.nih.gov/12742577
Autor:
Gabrielle S. Girouard, Sucheta Sircar, Johan E. van Lier, Cynthia M. Allen, Joseph M. Weber, Mounir Diouri
Publikováno v:
Virology. 224(2)
The catalytic activity of the adenovirus cysteine peptidase is increased by a specific 11-amino-acid peptide adduct (GVQSLKRRRCF, referred to as pVIc). To identify additional peptides which might bind and alter the activity of the protease, a cystein
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48cc53840d62b246df31e2b067e6289a
https://pubmed.ncbi.nlm.nih.gov/8874511
https://pubmed.ncbi.nlm.nih.gov/8874511
Publikováno v:
Antiviral research. 30(2-3)
The effect of a series of cysteine and serine protease inhibitors was tested on the growth of human adenovirus type 2 in tissue culture. In accordance with the nature of the adenovirus protease, only the cysteine protease inhibitors were effective in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3940db74ca7b8824ce38a740929bc04
https://pubmed.ncbi.nlm.nih.gov/8783806
https://pubmed.ncbi.nlm.nih.gov/8783806
Publikováno v:
JNCI Journal of the National Cancer Institute. 86:638-639
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d78f4cd5a05cb128861dbba260e8699
https://doi.org/10.1093/jnci/86.8.638
https://doi.org/10.1093/jnci/86.8.638
Proline 137 Is Critical for Adenovirus Protease Encapsidation and Activation but Not Enzyme Activity
Autor:
Hossein Keyvani-Amineh, Joseph M. Weber, Claudine Rancourt, Pascale Labrecque, Sucheta Sircar
Publikováno v:
Virology. (1):167-173
Infection with the adenovirus type 2 ts1 mutant at the nonpermissive temperature resulted in the production of noninfectious virions. This has been ascribed to the P137L mutation in the virus-encoded cysteine protease which causes a defect in proteas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ca48ef3d88a44ad63a597e584f4da01