Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Sucharita S. Somkuwar"'
Autor:
Sucharita S. Somkuwar, Leon W. Quach, Jacqueline A. Quigley, Dvijen C. Purohit, McKenzie J. Fannon, George F. Koob, Chitra D. Mandyam
Publikováno v:
Brain Sciences, Vol 8, Iss 7, p 119 (2018)
Lower impulse control is a known risk factor for drug abuse vulnerability. Chronic experience with illicit drugs is suggested to enhance impulsivity and thereby perpetuate addiction. However, the nature of this relationship (directionality, causality
Externí odkaz:
https://doaj.org/article/6608afb6f2ef4394b98d952bc2f9be72
Autor:
Chitra D. Mandyam, Emmanuel G. Villalpando, Noah L. Steiner, Leon W. Quach, McKenzie J. Fannon, Sucharita S. Somkuwar
Publikováno v:
Brain Sciences, Vol 7, Iss 10, p 131 (2017)
Alcoholism is a chronic relapsing disorder with few therapeutic strategies that address the core pathophysiology. Brain tissue loss and oxidative damage are key components of alcoholism, such that reversal of these phenomena may help break the addict
Externí odkaz:
https://doaj.org/article/ab344b6ee9b7484b866bde5433645ab6
Publikováno v:
Journal of Experimental Neuroscience, Vol 12 (2018)
Addictive drugs effect the brain reward circuitry by altering functional plasticity of neurons governing the circuits. Relapse is an inherent problem in addicted subjects and is associated with neuroplasticity changes in several brain regions includi
Externí odkaz:
https://doaj.org/article/33d4b3a7eb3645079b618fa25b9f53a9
Autor:
Sucharita S. Somkuwar, Chitra D. Mandyam, Leon W. Quach, Miriam Scadeng, Benjamin S. McKenna, Emmanuel G. Villalpando, Brian P. Head
Publikováno v:
Eur Neuropsychopharmacol
Previous studies demonstrate that ethanol dependence induced by repeating cycles of chronic intermittent ethanol vapor exposure (CIE) followed by protracted abstinence (CIE-PA) produces significant alterations in oligodendrogenesis in the rodent medi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::443bc177881234c43be438eaf4dc9be5
https://doi.org/10.1016/j.euroneuro.2020.11.010
https://doi.org/10.1016/j.euroneuro.2020.11.010
Autor:
Sucharita S. Somkuwar, Chitra D. Mandyam, Brian P. Head, Shanshan Wang, Alison D. Kreisler, Dvijen C. Purohit, Michael J. Terranova
Publikováno v:
Brain Struct Funct
This study sought to determine if reducing dopamine D1 receptor (D1R) expression in the dorsal striatum (DS) via RNA-interference alters methamphetamine self-administration. A lentiviral construct containing a short hairpin RNA (shRNA) was used to kn
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61175381419d9773a931951eeb345d31
https://doi.org/10.1007/s00429-020-02059-w
https://doi.org/10.1007/s00429-020-02059-w
Autor:
Wulfran Trenet, Nancy Xing, Britta D. Sibley, Sucharita S. Somkuwar, Sumaiya Olia, Alison D. Kreisler, Juan C. Piña-Crespo, Jacob R Watson, Chitra D. Mandyam, Yosef Avchalumov, Tejash Bharadwaj, Marisa Roberto, Amin A Shayan
Publikováno v:
Neuropsychopharmacology
Angiogenesis or proliferation of endothelial cells plays a role in brain microenvironment homeostasis. Previously we have shown enhanced expression of markers of angiogenesis in the medial prefrontal cortex during abstinence in an animal model of eth
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::664e7a5aa60c2f14fee02da8afc75e20
https://europepmc.org/articles/PMC8429630/
https://europepmc.org/articles/PMC8429630/
Autor:
Candice Contet, Sucharita S. Somkuwar, Jasmin Guevara, Eric P. Zorrilla, McKenzie J. Fannon, Chitra D. Mandyam, Tran Bao Nguyen, Leandro F. Vendruscolo, Brooke E. Schmeichel, Harpreet Sidhu
Publikováno v:
Psychoneuroendocrinology. 84:17-31
Alcohol dependence is linked to dysregulation of the hypothalamic-pituitary-adrenal axis. Here, we investigated effects of repeated ethanol intoxication-withdrawal cycles (using chronic intermittent ethanol vapor inhalation; CIE) and abstinence from
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03439859a8d1809cc78c077358e7aff2
https://doi.org/10.1016/j.psyneuen.2017.06.006
https://doi.org/10.1016/j.psyneuen.2017.06.006
Autor:
Chitra D. Mandyam, Kim D. Janda, Bryan W. Luikart, Jeffery C. Sobieraj, Melissa H. Galinato, Charles J. Heyser, Atoosa Ghofranian, George F. Koob, A Joea, Sucharita S. Somkuwar, Alvaro I. Navarro, S Chaing, Miranda C. Staples, McKenzie J. Fannon-Pavlich, Jonathan W. Lockner
Publikováno v:
Molecular psychiatry
Adult neurogenesis in the dentate gyrus (DG) is strongly influenced by drug-taking behavior and may have a role in the etiology of drug-seeking behavior. However, mechanistic studies on the relationship of neurogenesis on drug seeking are limited. Ou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::436a8415e5527682ac454f5185571da7
http://europepmc.org/articles/PMC5617764
http://europepmc.org/articles/PMC5617764
Publikováno v:
Brain Sciences
Volume 9
Issue 12
Volume 9
Issue 12
Chronic intermittent ethanol vapor exposure (CIE) in rodents produces reliable and high blood ethanol concentration and behavioral symptoms associated with moderate to severe alcohol use disorder (AUD)&mdash
for example, escalation of operant et
for example, escalation of operant et
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c529ffdc2121435541f82f0f4c8ff68
Autor:
Sucharita S. Somkuwar, Jacqueline A. Quigley, Atoosa Ghofranian, Melissa H. Galinato, Rahul R. Dutta, Chitra D. Mandyam, McKenzie J. Fannon-Pavlich
Publikováno v:
Brain, Behavior, and Immunity. 58:357-368
The therapeutic effects of wheel running (WR) during abstinence on reinstatement of ethanol seeking behaviors in rats that self-administered ethanol only (ethanol drinking, ED) or ED with concurrent chronic intermittent ethanol vapor experience (CIE-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee631661af81e871c122f75f1596a8d0
https://doi.org/10.1016/j.bbi.2016.08.006
https://doi.org/10.1016/j.bbi.2016.08.006