Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Sucharita Bose"'
Autor:
Mohammed Ahmad, Bhavya Jha, Sucharita Bose, Satish Tiwari, Abhisek Dwivedy, Deepshikha Kar, Ravikant Pal, Richard Mariadasse, Tanya Parish, Jeyaraman Jeyakanthan, Kutti R. Vinothkumar, Bichitra Kumar Biswal
Publikováno v:
IUCrJ, Vol 10, Iss 6, Pp 738-753 (2023)
Enolase, a ubiquitous enzyme, catalyzes the reversible conversion of 2-phosphoglycerate (2PG) to phosphoenolpyruvate (PEP) in the glycolytic pathway of organisms of all three domains of life. The underlying mechanism of the 2PG to PEP conversion has
Externí odkaz:
https://doaj.org/article/7df692bfcd31480da3280451dfbe08b4
Autor:
Sucharita Bose, C. Nicklaus Steussy, Daneli López-Pérez, Tim Schmidt, Samadhi C. Kulathunga, Mohamed N. Seleem, Mark Lipton, Andrew D. Mesecar, Victor W. Rodwell, Cynthia V. Stauffacher
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-13 (2023)
High-throughput in vitro screening and crystal structures identify a non-statin inhibitor of HMG-CoA reductase for novel antibacterial drug design.
Externí odkaz:
https://doaj.org/article/ff33f7666d8d44099aa084b1ad4f545f
Autor:
Gowtham Thambra Rajan Premageetha, KanagaVijayan Dhanabalan, Sucharita Bose, Lavanyaa Manjunath, Deepthi Joseph, Aviv Paz, Samuel Grandfield, Vinod Nayak, Luis M Bredeston, Jeff Abramson, Subramanian Ramaswamy
Publikováno v:
PLoS ONE, Vol 18, Iss 4, p e0280975 (2023)
Nucleotide Sugar Transporters (NSTs) belong to the SLC35 family (human solute carrier) of membrane transport proteins and are crucial components of the glycosylation machinery. NSTs are localized in the ER and Golgi apparatus membranes, where they ac
Externí odkaz:
https://doaj.org/article/2cd4d93a39b84696a8b261e4b63c513b
Autor:
Nitasha D. Menon, Megha S. Kumar, T. G. Satheesh Babu, Sucharita Bose, Gayathri Vijayakumar, Manasi Baswe, Meghna Chatterjee, Jovita Rowena D’Silva, Kavya Shetty, Jayalekshmi Haripriyan, Anil Kumar, Samitha Nair, Priyanka Somanath, Bipin G. Nair, Victor Nizet, Geetha B. Kumar
Publikováno v:
mSphere, Vol 6, Iss 1 (2021)
In India, multidrug resistance determinants are much more abundant in community-associated bacterial pathogens due to the improper treatment of domestic and industrial effluents. In particular, a high bacterial load of the opportunistic pathogen P. a
Externí odkaz:
https://doaj.org/article/9537f523ff7445a3be0a708c8e548838
Publikováno v:
Mongolian Journal of Biological Sciences, Vol 11, Iss 1-2, Pp 59-61 (2013)
Short horned grasshopper, Oxya velox were exposed to various doses of sodium arsenate and exhibit a signifi cant ( p < 0.05) dose dependent increase in protein of both gut wall and ovary. Study revealed that the amount of protein increased with th
Externí odkaz:
https://doaj.org/article/e882ca2913ea479fa2e03d98ac338bbf
Autor:
Joel C. Barrish, John Hynes, Ajay Saxena, Natesan Murugesan, Dianlin Xie, Anjaneya Chimalakonda, Stefan Ruepp, Mitalee Das, Richard Rampulla, Durgarao Kantheti, Chunhong Yan, Julie Carman, Jignesh Nagar, Siva Subramani, Qian Ruan, William J. Pitts, Rajeev S. Bhide, Paul A. Elzinga, Venkatram Reddy Paidi, John S. Sack, Mark Fereshteh, Thangavel Soodamani, Amrita Jha Mukherjee, T. Thanga Mariappan, Ramesh Kumar Sistla, Kaushik Ghosh, Debarati Mazumder, Kamalavenkatesh Palanisamy, Deborah A. Holloway, Susan E. Kiefer, John A. Newitt, Satheesh Kesavan Nair, Polimera Subba Rao, Shailesh Dudhgoankar, Percy H. Carter, Xin Li, Srinivas Maddi, S. Pon Saravanakumar, Sreekantha Ratna Kumar, Sucharita Bose
Publikováno v:
ACS Med Chem Lett
[Image: see text] IRAK4 is an attractive therapeutic target for the treatment of inflammatory conditions. Structure guided optimization of a nicotinamide series of inhibitors has been expanded to explore the IRAK4 front pocket. This has resulted in t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24bbdf7e3f4256a866250ac0c4fba45e
https://doi.org/10.1021/acsmedchemlett.0c00082
https://doi.org/10.1021/acsmedchemlett.0c00082
Autor:
Mohammed Ahmad, Bhavya Jha, Sucharita Bose, Satish Tiwari, Abhisek Dwivedy, Deepshikha Kar, Ravikant Pal, Richard Mariadasse, Tanya Parish, Jeyaraman Jeyakanthan, Kutti R. Vinothkumar, Bichitra Kumar Biswal
Publikováno v:
SSRN Electronic Journal.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2b0eda2743c3d7942a7d33f3133c07ff
https://doi.org/10.2139/ssrn.4105356
https://doi.org/10.2139/ssrn.4105356
Publikováno v:
Acta Crystallographica. Section D, Structural Biology
CMP-N-acetylneuraminate synthetase (CMAS) is a key enzyme in the sialic acid incorporation pathway and plays a crucial role in the virulence and survival of several pathogenic bacteria. Here, the structural and functional properties of CMAS from the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b18c93f7e1fb651d083fe896035add1
http://europepmc.org/articles/PMC6580227
http://europepmc.org/articles/PMC6580227
Autor:
Jayalekshmi Haripriyan, Priyanka Somanath, Sucharita Bose, Kavya Shetty, Gayathri Vijayakumar, Jovita Rowena D’Silva, Bipin G. Nair, Manasi Baswe, Nitasha D. Menon, Samitha Nair, Megha S. Kumar, T.G. Satheesh Babu, Geetha B. Kumar, Meghna Chatterjee, Victor Nizet, Anil Kumar
Publikováno v:
mSphere
mSphere, Vol 6, Iss 1 (2021)
mSphere, Vol 6, Iss 1 (2021)
In India, multidrug resistance determinants are much more abundant in community-associated bacterial pathogens due to the improper treatment of domestic and industrial effluents. In particular, a high bacterial load of the opportunistic pathogen P. a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd0bc4fbd35910e098a1d1a3f13a8839
https://doi.org/10.1128/msphere.01215-20
https://doi.org/10.1128/msphere.01215-20
Autor:
Mugdha Dhurandhar, Ramanathan Sowdhamini, S. Ramaswamy, Sucharita Bose, Renwick C. J. Dobson, Vikas Tiwari, David Coombes, Lavanyaa Manjunath, James S Davies
Publikováno v:
ProteinsREFERENCES.
N-acetylglucosamine 6-phosphate deacetylase (NagA) catalyzes the conversion of N-acetylglucosamine-6-phosphate to glucosamine-6-phosphate in amino sugar catabolism. This conversion is an essential step in the catabolism of sialic acid in several path
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e83a5b575eec7fc33033f6f6c5e52321
https://pubmed.ncbi.nlm.nih.gov/32865821
https://pubmed.ncbi.nlm.nih.gov/32865821