Sex-specific metabolic alterations in the type 1 diabetic brain of mice revealed by an integrated method of metabolomics and mixed-model

Autor: Hongchang Gao, Liangcai Zhao, Qingqing Xu, Junjie Yan, Yafei Zheng, Hangying Xu, Chen Li, Qiaoying Jiang, Hong Zheng

Publikováno v: Computational and Structural Biotechnology Journal, Vol 18, Iss, Pp 2063-2074 (2020)
Computational and Structural Biotechnology Journal

Graphical abstract
Highlights • Sex-specific metabolic differences occur in all brain regions of mice. • The hippocampal metabolism is more susceptible to T1D. • Metabolic disorders start at the cortex and hippocampus in female T1D mice. �

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26f4f182a76ce782a14533b123602dc5
http://www.sciencedirect.com/science/article/pii/S2001037020303512

Short-chain fatty acids reprogram metabolic profiles with the induction of reactive oxygen species production in human colorectal adenocarcinoma cells.

Autor: Huang C; State Key Laboratory of Magnetic Resonance and Atomic and Molecular Physics, Innovation Academy for Precision Measurement Science and Technology, Chinese Academy of Sciences, Wuhan, China., Deng W; Wuhan Botanical Garden, Chinese Academy of Sciences, Wuhan, Hubei, China., Xu HZ; Department of Pediatrics, Division of Infectious Diseases, College of Medicine, University of Florida, Gainesville, FL, USA., Zhou C; Wuhan Botanical Garden, Chinese Academy of Sciences, Wuhan, Hubei, China., Zhang F; Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan, China., Chen J; State Key Laboratory of Magnetic Resonance and Atomic and Molecular Physics, Innovation Academy for Precision Measurement Science and Technology, Chinese Academy of Sciences, Wuhan, China., Bao Q; State Key Laboratory of Magnetic Resonance and Atomic and Molecular Physics, Innovation Academy for Precision Measurement Science and Technology, Chinese Academy of Sciences, Wuhan, China.; University of Chinese Academy of Sciences, Beijing, China., Zhou X; State Key Laboratory of Magnetic Resonance and Atomic and Molecular Physics, Innovation Academy for Precision Measurement Science and Technology, Chinese Academy of Sciences, Wuhan, China.; University of Chinese Academy of Sciences, Beijing, China.; Optics Valley Laboratory, Hubei 430074, China., Liu M; State Key Laboratory of Magnetic Resonance and Atomic and Molecular Physics, Innovation Academy for Precision Measurement Science and Technology, Chinese Academy of Sciences, Wuhan, China.; University of Chinese Academy of Sciences, Beijing, China.; Optics Valley Laboratory, Hubei 430074, China., Li J; Wuhan Botanical Garden, Chinese Academy of Sciences, Wuhan, Hubei, China.; University of Chinese Academy of Sciences, Beijing, China., Liu C; State Key Laboratory of Magnetic Resonance and Atomic and Molecular Physics, Innovation Academy for Precision Measurement Science and Technology, Chinese Academy of Sciences, Wuhan, China.; University of Chinese Academy of Sciences, Beijing, China.; Optics Valley Laboratory, Hubei 430074, China.

Publikováno v: Computational and structural biotechnology journal [Comput Struct Biotechnol J] 2023 Feb 13; Vol. 21, pp. 1606-1620. Date of Electronic Publication: 2023 Feb 13 (Print Publication: 2023).

Interaction of storage carbohydrates and other cyclic fluxes with central metabolism: A quantitative approach by non-stationary ¹³ C metabolic flux analysis.

Autor: Suarez-Mendez CA; Department of Biotechnology, Delft University of Technology, Julianalaan 67 - 2628 BC Delft, The Netherlands.; Kluyver Centre for Genomics of Industrial Fermentation, P.O. Box 5057, 2600 GA Delft, The Netherlands., Hanemaaijer M; Department of Biotechnology, Delft University of Technology, Julianalaan 67 - 2628 BC Delft, The Netherlands., Ten Pierick A; Department of Biotechnology, Delft University of Technology, Julianalaan 67 - 2628 BC Delft, The Netherlands.; Department of Biotechnology, Delft University of Technology, Julianalaan 67 - 2628 BC Delft, The Netherlands., Wolters JC; Department of Analytical Biochemistry, University of Groningen, Antonius Deusinglaan 1, 9713 AV Groningen, The Netherlands., Heijnen JJ; Department of Biotechnology, Delft University of Technology, Julianalaan 67 - 2628 BC Delft, The Netherlands.; Kluyver Centre for Genomics of Industrial Fermentation, P.O. Box 5057, 2600 GA Delft, The Netherlands., Wahl SA; Department of Biotechnology, Delft University of Technology, Julianalaan 67 - 2628 BC Delft, The Netherlands.; Kluyver Centre for Genomics of Industrial Fermentation, P.O. Box 5057, 2600 GA Delft, The Netherlands.

Publikováno v: Metabolic engineering communications [Metab Eng Commun] 2016 Jan 22; Vol. 3, pp. 52-63. Date of Electronic Publication: 2016 Jan 22 (Print Publication: 2016).