Výsledky vyhledávání - "Subsequent therapy"

Akademický článek

A real-world study of treatment patterns following disease progression in epithelial ovarian cancer patients undergoing poly-ADP-ribose polymerase inhibitor maintenance therapy

Autor: Nan Zhang, Hong Zheng, Yunong Gao, Tong Shu, Hongguo Wang, Yan Cai

Publikováno v: Journal of Ovarian Research, Vol 17, Iss 1, Pp 1-9 (2024)

Abstract Background The efficacy of subsequent therapy after poly-ADP-ribose polymerase (PARP) inhibitor maintenance treatment has raised concerns. Retrospective studies show worse outcomes for platinum-based chemotherapy after progression of PARP in

Externí odkaz: https://doaj.org/article/f56f3cdae58441df84ae945584799874

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Akademický článek

Real-world outcomes on platinum-containing chemotherapy for EGFR-mutated advanced nonsquamous NSCLC with prior exposure to EGFR tyrosine kinase inhibitors

Autor: Balazs Halmos, Pragya Rai, Jae Min, Xiaohan Hu, Diana Chirovsky, Mark Shamoun, Bin Zhao

Publikováno v: Frontiers in Oncology, Vol 14 (2024)

BackgroundFront-line therapy with an EGFR tyrosine kinase inhibitor (TKI) is the standard of care for treating patients with advanced nonsquamous NSCLC with the common sensitizing EGFR exon 19 deletion and exon 21 L858R point mutations. However, EGFR

Externí odkaz: https://doaj.org/article/fb5767149c164328a59f9b0bf817f5a6

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Akademický článek

Real-world treatment patterns of subsequent therapy after palbociclib in patients with advanced breast cancer in Japan

Autor: Masataka Sawaki, Yasuaki Muramatsu, Kanae Togo, Hiroji Iwata

Publikováno v: Breast, Vol 70, Iss , Pp 1-7 (2023)

Purpose: The optimal treatment following endocrine therapy (ET) plus a cyclin-dependent kinase 4/6 inhibitor (CDK4/6i) has not been established. We aimed to investigate treatment patterns and time to treatment failure (TTF) of subsequent therapy afte

Externí odkaz: https://doaj.org/article/1e0f5ed4fb38406e9e37439d595dbcab

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Akademický článek

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Akademický článek

Efficacy of Osimertinib After Progression of First-Generation Epidermal Growth Factor Receptor-Tyrosine Kinase Inhibitor (EGFR-TKI) in EGFR-Mutated Lung Adenocarcinoma: A Real-World Study in Chinese Patients

Autor: Xu Z, Hao X, Wang Q, Wang J, Yang K, Wang S, Teng F, Li J, Xing P

Publikováno v: Cancer Management and Research, Vol Volume 14, Pp 863-873 (2022)

Ziyi Xu,1,* Xuezhi Hao,1,* Qi Wang,2 Jing Wang,2 Ke Yang,3 Shouzheng Wang,1 Fei Teng,1 Junling Li,1 Puyuan Xing1 1Department of Medical Oncology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Aca

Externí odkaz: https://doaj.org/article/2d00e96d76d94556bba5aaf488692205

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Akademický článek

Estimation of Overall Survival with Subsequent Treatment Effect by Applying Inverse Probability of Censoring Weighting in the LATITUDE Study

Autor: Yosuke Koroki, Masataka Taguri, Nobuaki Matsubara, Karim Fizazi

Publikováno v: European Urology Open Science, Vol 36, Iss , Pp 51-58 (2022)

Background: In the LATITUDE study (ClinicalTrials.gov, NCT01715285), compared with placebos, abiraterone acetate plus prednisone (AAP) with androgen deprivation therapy (ADT) provided significant overall survival (OS) benefit in high-risk metastatic

Externí odkaz: https://doaj.org/article/cef3319bf1794cedbd054d9131dfe829

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Efficacy and safety profile of combining programmed cell death‐1 (PD‐1) inhibitors and antiangiogenic targeting agents as subsequent therapy for advanced or metastatic non‐small cell lung cancer (NSCLC)

Autor: Ziyi Xu, Teng Li, Xingsheng Hu, Xuezhi Hao, Puyuan Xing, Junling Li

Publikováno v: Thoracic Cancer, Vol 12, Iss 17, Pp 2360-2368 (2021)

Abstract Background Previous studies have demonstrated that PD‐1 inhibitors are effective in the treatment of advanced or metastatic non‐small cell lung cancer (NSCLC). However, whether the combination of PD‐1 inhibitors and antiangiogenic agen

Externí odkaz: https://doaj.org/article/8ad1f830323e4f72be972e08b029e231

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Akademický článek

Association of perioperative adverse events with subsequent therapy and overall survival in patients with WHO grade III and IV gliomas

Autor: Lorenz Weber, Luis Padevit, Timothy Müller, Julia Velz, Flavio Vasella, Stefanos Voglis, Dorothee Gramatzki, Michael Weller, Luca Regli, Johannes Sarnthein, Marian Christoph Neidert

Publikováno v: Frontiers in Oncology, Vol 12 (2022)

BackgroundMaximum safe resection followed by chemoradiotherapy as current standard of care for WHO grade III and IV gliomas can be influenced by the occurrence of perioperative adverse events (AE). The aim of this study was to determine the associati

Externí odkaz: https://doaj.org/article/6525ca90fc9d4dd893650f5b90c9c4c7

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