Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Subreen Khatib"'
Autor:
Lichun Ma, Sophia Heinrich, Limin Wang, Friederike L. Keggenhoff, Subreen Khatib, Marshonna Forgues, Michael Kelly, Stephen M. Hewitt, Areeba Saif, Jonathan M. Hernandez, Donna Mabry, Roman Kloeckner, Tim F. Greten, Jittiporn Chaisaingmongkol, Mathuros Ruchirawat, Jens U. Marquardt, Xin Wei Wang
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-17 (2022)
Multiregion sequencing is needed to better capture the heterogeneity of hepatocellular carcinoma (HCC) and intrahepatic cholangiocarcinoma (iCCA). Here, the authors analyse HCC and iCCA tumours with multiregion single-cell RNA-seq, revealing cellular
Externí odkaz:
https://doaj.org/article/f2ebde2426ee4ec09a8cd16dac1ffe6f
Autor:
Sean P. Martin, Valerie Fako, Hien Dang, Dana A. Dominguez, Subreen Khatib, Lichun Ma, Haiyang Wang, Wei Zheng, Xin Wei Wang
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 39, Iss 1, Pp 1-15 (2020)
Abstract Background Therapeutic options for patients with hepatocellular carcinoma (HCC) are limited. Transarterial chemoembolization (TACE) is an interventional procedure used to deliver chemotherapy and embolizing agents directly to the tumor and i
Externí odkaz:
https://doaj.org/article/75bc95afc64442bd82083cb89e806b55
Autor:
Hien Dang, Xin Wei Wang, Adam S. Bodzin, Ashesh P. Shah, Ravinder Parhar, Dana A. Dominguez, Marshonna Forgues, Lucy Knight, Subreen Khatib, Sean P. Martin, Anna E. Barry, Yotsawat Pomyen, Kai Zhang
Supplementary Materials and Methods
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3461b9414eeecbe523704290b23e0e84
https://doi.org/10.1158/1541-7786.22513767
https://doi.org/10.1158/1541-7786.22513767
Autor:
Hien Dang, Xin Wei Wang, Adam S. Bodzin, Ashesh P. Shah, Ravinder Parhar, Dana A. Dominguez, Marshonna Forgues, Lucy Knight, Subreen Khatib, Sean P. Martin, Anna E. Barry, Yotsawat Pomyen, Kai Zhang
Supplementary Figures S1-S6 and Immunoblots
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c3b0d808e6edcab968cc9771664ccea
https://doi.org/10.1158/1541-7786.22513770.v1
https://doi.org/10.1158/1541-7786.22513770.v1
Autor:
Hien Dang, Xin Wei Wang, Adam S. Bodzin, Ashesh P. Shah, Ravinder Parhar, Dana A. Dominguez, Marshonna Forgues, Lucy Knight, Subreen Khatib, Sean P. Martin, Anna E. Barry, Yotsawat Pomyen, Kai Zhang
Supplemental Table S1. Correlation between differentially expressed miRNAs (DEmiRNAs) and differentially expressed mRNAs (DEmRNAs) in the TCGA dataset.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a6dd8170d6bbe25252738a53ac1c293
https://doi.org/10.1158/1541-7786.22513764.v1
https://doi.org/10.1158/1541-7786.22513764.v1
Autor:
Xin Wei Wang, Snorri S. Thorgeirsson, Xiaoling Luo, Gary A. Mitchell, Jinqiu Chen, Lun-Xiu Qin, Hu-Liang Jia, Qing-Hai Ye, Katie Powell, Xiaolin Wu, Rachel Bagni, Ji Luo, Dana A. Dominguez, Sean P. Martin, Subreen Khatib, Naoki Oishi, Hien Dang, Atsushi Takai
Hepatocellular carcinoma (HCC) is a genetically heterogeneous disease for which a dominant actionable molecular driver has not been identified. Patients with the stem cell–like EpCAM+AFP+ HCC subtype have poor prognosis. Here, we performed a genome
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6f2a0432334f4af63a322ad93bdcf9ad
https://doi.org/10.1158/0008-5472.c.6511490.v1
https://doi.org/10.1158/0008-5472.c.6511490.v1
Autor:
Xin Wei Wang, Snorri S. Thorgeirsson, Xiaoling Luo, Gary A. Mitchell, Jinqiu Chen, Lun-Xiu Qin, Hu-Liang Jia, Qing-Hai Ye, Katie Powell, Xiaolin Wu, Rachel Bagni, Ji Luo, Dana A. Dominguez, Sean P. Martin, Subreen Khatib, Naoki Oishi, Hien Dang, Atsushi Takai
Supplementary figures as related to the manuscript. Data represent schematic RNAi screen workflow, additional survival analyses, and experiments performed in different hepatocellular carcinoma cell lines.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0869c2e4aa8f214523b643af5b4cd6bd
https://doi.org/10.1158/0008-5472.22423391.v1
https://doi.org/10.1158/0008-5472.22423391.v1
Publikováno v:
Seminars in Liver Disease. 41:321-330
Single-cell technologies are revolutionizing our understanding of cellular heterogeneity and functional diversity in health and disease. Here, we review the current knowledge and advances in liver biology using single-cell approaches. We focus on the
Autor:
Martin, Sean P., Fako, Valerie, Dang, Hien, Dominguez, Dana A., Subreen Khatib, Lichun Ma, Haiyang Wang, Zheng, Wei, Wang, Xin Wei
Additional file 1:Table S1. IC50 Concentrations Used For Invitro Experiments. Table S2. Univariable and Multivariable Cox Proportional Hazards Model of LCI cohort. Figure S1. Gene expression and survival analysis of gluconeogenesis related genes corr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a0e25498c4d71a4107d89a5748689d3
Autor:
Kai, Zhang, Yotsawat, Pomyen, Anna E, Barry, Sean P, Martin, Subreen, Khatib, Lucy, Knight, Marshonna, Forgues, Dana A, Dominguez, Ravinder, Parhar, Ashesh P, Shah, Adam S, Bodzin, Xin Wei, Wang, Hien, Dang
Publikováno v:
Mol Cancer Res
Deregulated RNA binding proteins (RBPs), such as Argonaute 2 (AGO2) mediate tumor-promoting transcriptomic changes during carcinogenesis, including hepatocellular carcinoma (HCC). While AGO2 is well characterized as a member of the RNA-induced silenc