Zobrazeno 1 - 10
of 147
pro vyhledávání: '"Subrata Deb"'
Publikováno v:
Diseases, Vol 12, Iss 5, p 107 (2024)
COVID-19 infection is caused by the novel severe acute respiratory syndrome coronavirus 2 (SAR-CoV-2). This novel virus has transformed into different resistant variants (e.g., omicron; delta; alpha; epsilon) since its first emergence in 2019. The Na
Externí odkaz:
https://doaj.org/article/0597bd44bb01483ab3bf66645e51f483
Publikováno v:
Current Issues in Molecular Biology, Vol 45, Iss 5, Pp 4301-4316 (2023)
Heme oxygenase 1 (HO-1) is a detoxifying antioxidant microsomal enzyme that regulates inflammation, apoptosis, cell proliferation, and angiogenesis in prostate cancer (PCa). This makes HO-1 a promising target for therapeutic prevention and treatment
Externí odkaz:
https://doaj.org/article/2d97e104dcd84abd8ca5ce0ea3e6b4ad
Autor:
Mohamed Ben-Eltriki, Erysa J. Gayle, Jhoanne M. Paras, Louisa Nyame-Addo, Manik Chhabra, Subrata Deb
Publikováno v:
Life, Vol 14, Iss 4, p 510 (2024)
Vitamin D is a promising anticancer agent for the prevention and treatment of several cancers, including melanoma. Low 25-hydroxyvitamin D levels, a routinely used marker for vitamin D, have been suggested as one of the factors in the development and
Externí odkaz:
https://doaj.org/article/a3dad9565a8e471db7ace5ec2f36d5af
Publikováno v:
Medicines, Vol 11, Iss 3, p 6 (2024)
Pharmacogenomics (PGx) can facilitate the transition to patient-specific drug regimens and thus improve their efficacy and reduce toxicity. The aim of this study was to evaluate the overlap of PGx classification for drug absorption, distribution, met
Externí odkaz:
https://doaj.org/article/1db11be015b04ae0801a89e9ccd80f64
Publikováno v:
Biomedicines, Vol 11, Iss 7, p 1867 (2023)
Sodium-glucose cotransporter 2 (SGLT2) serves as a critical glucose transporter that has been reported to be overexpressed in cancer models, followed by increased glucose uptake in both mice and humans. Inhibition of its expression can robustly thwar
Externí odkaz:
https://doaj.org/article/e3fbcde95ccd4debbdcf72403ab1f1c1
Publikováno v:
Medicines, Vol 10, Iss 3, p 21 (2023)
Background: Abiraterone acetate is a cytochrome P450 17A1 (CYP17A1) inhibitor that is indicated for use in both castration-resistant and castration-sensitive prostate cancer patients. To manage the mineralocorticoid effects of CYP17A1 inhibition, a g
Externí odkaz:
https://doaj.org/article/9b0984a48d574da4ae96188e4f2b728b
Publikováno v:
Journal of Pharmacy & Pharmaceutical Sciences, Vol 25 (2022)
Purpose: Vitamin D has immunomodulatory properties that can be useful in COVID-19 patients. We performed a meta-analysis of observational studies to analyze the association of vitamin D levels with the inflammatory markers in COVID-19 patients. Metho
Externí odkaz:
https://doaj.org/article/af4a15ad7a2a460bb15c369c93059407
Publikováno v:
Life, Vol 12, Iss 10, p 1607 (2022)
The incidence and mortality from prostate cancer (PCa) are on the rise which poses a major public health concern worldwide. In this narrative review, we have summarized the characteristics of major in vitro and in vivo PCa models including their util
Externí odkaz:
https://doaj.org/article/ed455952c2a04f6d9acac25b15169490
Autor:
Prashant Sakharkar, Subrata Deb
Publikováno v:
Journal of Pharmacy & Pharmaceutical Sciences, Vol 24, Iss 3 (2021)
Purpose: Hyperglycemia is the hallmark of various types of diabetes and considered to be a risk factor for several chronic disorders including liver function. Though liver is a dynamic organ, incessant glucotoxicity can lead to altered liver function
Externí odkaz:
https://doaj.org/article/ff97fd5db1bd4ac095241eff1197d445
Autor:
Subrata Deb, Anthony Allen Reeves
Publikováno v:
Journal of Pharmacy & Pharmaceutical Sciences, Vol 24, Iss 3 (2021)
Purpose: Remdesivir, a drug originally developed against Ebola virus, is currently recommended for patients hospitalized with coronavirus disease of 2019 (COVID-19). In spite of United States Food and Drug Administration’s recent assent of remdesiv
Externí odkaz:
https://doaj.org/article/1060e40b1dd0444fabaccf17304df17f