Zobrazeno 1 - 10
of 1 922
pro vyhledávání: '"Subra, P"'
Autor:
Shanta Murthy, Murugadas Anbazhagan, Sushma Chowdary Maddipatla, Vasantha L. Kolachala, Anne Dodd, Ranjit Pelia, David J. Cutler, Jason D. Matthews, Subra Kugathasan
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)
Abstract Perianal fistulizing Crohn’s disease (CD) is a severe gastrointestinal disorder causing extensive mucosal damage with limited treatment options. Severe manifestations of the disease appear at higher rates in non-Europeans but the genetic a
Externí odkaz:
https://doaj.org/article/9e986aae16f04da0b37b685264521a99
PTGER4 signaling regulates class IIa HDAC function and SPINK4 mRNA levels in rectal epithelial cells
Autor:
Murugadas Anbazhagan, Garima Sharma, Shanta Murthy, Sushma Chowdary Maddipatla, Vasantha L. Kolachala, Anne Dodd, Amanda Randunne, David J. Cutler, Subra Kugathasan, Jason D. Matthews
Publikováno v:
Cell Communication and Signaling, Vol 22, Iss 1, Pp 1-14 (2024)
Abstract Background The prostaglandin receptor PTGER4 facilitates homeostasis in the gut. Previous reports indicate that goblet cells, marked by SPINK4 expression, might be affected by PTGER4 activity. Current evidence suggests that prostaglandin E2
Externí odkaz:
https://doaj.org/article/703b6ce950e24a41929fb944510436e4
Autor:
Bao, Shunxing, Zhu, Sichen, Kolachala, Vasantha L, Remedios, Lucas W., Hwang, Yeonjoo, Sun, Yutong, Deng, Ruining, Cui, Can, Li, Yike, Li, Jia, Roland, Joseph T., Liu, Qi, Lau, Ken S., Kugathasan, Subra, Qiu, Peng, Wilson, Keith T., Coburn, Lori A., Landman, Bennett A., Huo, Yuankai
Crohn's disease (CD) is a chronic and relapsing inflammatory condition that affects segments of the gastrointestinal tract. CD activity is determined by histological findings, particularly the density of neutrophils observed on Hematoxylin and Eosin
Externí odkaz:
http://arxiv.org/abs/2308.10166
Publikováno v:
Physical Review Fluids, 2022, 7 (12), pp.124302
We experimentally investigate the behaviour of instantaneous localised releases of heavy particles falling as turbulent clouds in quiescent water, both with and without background rotation. We present the results of 514 systematic experiments for no
Externí odkaz:
http://arxiv.org/abs/2301.06963
Autor:
Dominik Aschenbrenner, Isar Nassiri, Suresh Venkateswaran, Sumeet Pandey, Matthew Page, Lauren Drowley, Martin Armstrong, Subra Kugathasan, Benjamin Fairfax, Holm H. Uhlig
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-13 (2024)
Abstract Despite major advances in linking single genetic variants to single causal genes, the significance of genetic variation on transcript-level regulation of expression, transcript-specific functions, and relevance to human disease has been poor
Externí odkaz:
https://doaj.org/article/a2f66ea234664d8faf2951ab66b8f269
Publikováno v:
Frontiers in Public Health, Vol 12 (2024)
Background/purposePoor oral hygiene and periodontal disease have been identified as potential risk factors for the coronavirus disease 2019 (COVID-19). The present study aimed to determine the association between periodontitis and COVID-19 severity,
Externí odkaz:
https://doaj.org/article/d64c9fb5765e436984dd54e586fcb2f7
Autor:
Muhammad Hammad Hussain, Subra Sajid, Maria Martuscelli, Waleed Aldahmash, Muhammad Zubair Mohsin, Kamran Ashraf, Meijin Guo, Ali Mohsin
Publikováno v:
Heliyon, Vol 10, Iss 14, Pp e34366- (2024)
This study aimed to evaluate the hydrolysates from orange peel waste (OPW) as the low-cost carbon source for lycopene production. Initially, the dilute acid pretreatment combined with enzymatic hydrolysis of OPW resulted in a total sugar concentratio
Externí odkaz:
https://doaj.org/article/45c6a181d796454986717cc3bb1d8abc
Publikováno v:
International Journal of Nanomedicine, Vol Volume 19, Pp 2199-2225 (2024)
Arif Budiman,1 Gracia Anastasya,1 Annisa Luthfiyah Handini,1 Ira Novianty Lestari,2 Laila Subra,3 Diah Lia Aulifa2 1Department of Pharmaceutics and Pharmaceutical Technology, Universitas Padjadjaran, Bandung, Indonesia; 2Department of Pharmaceutical
Externí odkaz:
https://doaj.org/article/ce31db62219a4f5d898b2f2757f2912b
Autor:
Dr. Tharwat Mohy El‐Dine, Matthieu Lavayssiere, Dr. Hélène Adihou, Prof. Gilles Subra, Dr. Thomas‐Xavier Métro, Dr. Olivier Ludemann‐Hombourger, Dr. Frédéric Lamaty
Publikováno v:
ChemistryEurope, Vol 2, Iss 3-4, Pp n/a-n/a (2024)
Abstract The solventless synthesis of peptides from unactivated amino acids was optimized in a twin‐screw extruder (TSE). The general method enabled the preparation of dipeptides and tripeptides with no epimerization. This flow mechanochemistry app
Externí odkaz:
https://doaj.org/article/a0586154c9b746baa52026f88bcb14df
Autor:
Christopher Moriates, Michael Pignone, Nidharshan Subra Anandasivam, Jaya Vasudevan, Holli Sadler
Publikováno v:
BMJ Open Quality, Vol 13, Iss 2 (2024)
Clinical practice guidelines recommend screening for primary hyperaldosteronism (PH) in patients with resistant hypertension. However, screening rates are low in the outpatient setting. We sought to increase screening rates for PH in patients with re
Externí odkaz:
https://doaj.org/article/2648056e5d0247e592b91231254e8c0d