Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Subimal Basu"'
Autor:
Richard Letourneau, Pamela Esposito, Stanley Jacobson, Subimal Basu, Theoharis C. Theoharides
Publikováno v:
Brain Research. 968:192-198
Stress activates the hypothalamic–pituitary–adrenal (HPA) axis through release of corticotropin releasing factor (CRF), leading to production of glucocorticoids that down regulate immune responses. However, acute stress via CRF also has pro-infla
Publikováno v:
Biochemical and Biophysical Research Communications. 247:79-83
The NFkB transcription factor is activated by diverse stimuli, including Ionizing Radiation (IR) and the cytokine TNF alpha. The role of DNA-PK, a protein kinase involved in the response to DNA damage, in the activation of NF kappa B by IR and TNF al
Publikováno v:
Biochemical and Biophysical Research Communications. 245:514-518
The C-terminal of p53 (amino-acids 368-383) represses the DNA binding activity of p53. In vitro, phosphorylation of this region by Protein Kinase C (PKC) is associated with increased DNA binding activity. However, whether PKC can directly modulate p5
Autor:
Pamela Esposito, Nathan Chandler, Kristiana Kandere, Subimal Basu, Stanley Jacobson, David Tutor, Theoharis C. Theoharides, Raymond J. Connolly
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 303(3)
Stress activates the hypothalamic-pituitary-adrenal axis through release of corticotropin releasing hormone (CRH), leading to production of glucocorticoids that down-regulate immune responses. Acute stress, however, also has proinflammatory effects t
Autor:
Duraisamy Kempuraj, Achilles Athanassiou, Kristiana Kandere-Grzybowska, Theoharis C. Theoharides, Man Huang, Subimal Basu, William Boucher, Richard Letourneau
Publikováno v:
International archives of allergy and immunology. 132(3)
Background: Mast cells are involved in allergic inflammation by secreting histamine, proteases and several cytokines, including interleukin (IL)-6, tumor necrosis factor-α (TNF-α) and IL-8. Certain histamine-1 receptor antagonists, such as azelasti
Publikováno v:
European journal of pharmacology. 371(2-3)
Several phosphoproteins are involved in stimulus-secretion coupling. The beta and gamma subunits of immunoglobulin E binding protein (FC epsilonRI) and three other protein bands get phosphorylated during stimulation of mast cell secretion. These addi