Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Subhendu Karmakar"'
Publikováno v:
Chemistry – A European Journal. 26:9475-9480
The oxidation of cis-[Pt(NH3 )2 (OAc)2 ] with H2 O2 yields a mixture of two isomers: ctc-[Pt(NH3 )2 (OH)2 (OAc)2 ] and ctc-[Pt(NH3 )2 (OH)(OAc)(OH)(OAc)]. Following modification with 4-phenylbutyric (PhB) anhydride, two isomers were separated and cha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fba28425c5f60dd6b662ef6c5d355c09
https://doi.org/10.1002/chem.202001472
https://doi.org/10.1002/chem.202001472
Publikováno v:
Inorganic Chemistry. 59:5182-5193
Multiaction Pt(IV) prodrugs can overcome resistance associated with the FDA approved Pt(II) drugs like cisplatin. Intracellular reduction of the octahedral Pt(IV) derivatives of cisplatin releases cisplatin and the two axial ligands. When the release
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7fbabb61d8e913986301e052fd0a7f9
https://doi.org/10.1021/acs.inorgchem.0c00445
https://doi.org/10.1021/acs.inorgchem.0c00445
Publikováno v:
Dalton Transactions. 49:2547-2558
Pt(II) drugs and nitrogen mustards display severe side effects, poor tumour selectivity and face growing resistance by cancer cells due to sequestration by the thiol-containing molecules (viz. glutathione (GSH) and the copper ATPases like ATP7A/7B).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5503a3e68971b3ccd59509f8b739e95d
https://doi.org/10.1039/c9dt04269e
https://doi.org/10.1039/c9dt04269e
Autor:
Subhendu Karmakar
Human civilization is now facing the biggest pandemic of coronavirus disease 2019 (COVID-19) of this century caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Absence of any suitable vaccines makes this virus much more detriment
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::abbaa48015a032c4ea1b194f4b3f6ae0
https://doi.org/10.1016/b978-0-323-85844-1.00013-1
https://doi.org/10.1016/b978-0-323-85844-1.00013-1
Autor:
Balogun Muhsin Adekunle, Varun Agiwal, null Anisuzzaman, Ali-Erin Balikel, Georges Bellos, Swarnav Bhakta, Arijit Bhattacharya, Shatarupa Biswas, Debleena Biswas, Folami Ahmadu Bolanle, Dibyajnan Chakraborty, Pyali Chatterjee, Saptarshi Chatterjee, Suvendu Choudhury, Megha Dutta, Sanmitra Ghosh, Zobayda Farzana Haque, Viana Hassan, Muhammad Tofazzal Hossain, Hadeya Jeha, Subhendu Karmakar, Mohamad Knio, Ashok Kumar, Jitendra Kumar, Saurabh Kumar, Tanmay Majumdar, Budhaditya Mukherjee, Riaz Ahmad Saeed, Amulya K. Panda, Joydeep Paul, Asha Shelly, null Snehlata, Kora Bhanu Teja, Prabhat Trivedi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3b3ea67525795df8513d4a0d3bb63845
https://doi.org/10.1016/b978-0-323-85844-1.01002-3
https://doi.org/10.1016/b978-0-323-85844-1.01002-3
Publikováno v:
Dalton Transactions. 48:1144-1160
The alkylating agents bearing the -N(CH2CH2Cl)2 moiety, commonly known as 'the nitrogen mustards,' are among the first chemotherapeutic agents against cancer. They form covalent alkyl linkages due to reaction with nucleophilic entities viz. N7 of gua
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de522f4a95c4277cdea282795b28a005
https://doi.org/10.1039/c8dt04503h
https://doi.org/10.1039/c8dt04503h
Publikováno v:
Inorganic chemistry. 58(24)
Pt(II) complexes, such as cisplatin and oxaliplatin, are in widespread use as anticancer drugs. Their use is limited by the toxic side effects and the ability of tumors to develop resistance to the drugs. A popular approach to overcome these drawback
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb30770e811da6d268db99d47c5b651f
https://pubmed.ncbi.nlm.nih.gov/31790216
https://pubmed.ncbi.nlm.nih.gov/31790216
Autor:
Thirumal, Yempala, Tomer, Babu, Subhendu, Karmakar, Alina, Nemirovski, Maisaloon, Ishan, Valentina, Gandin, Dan, Gibson
Publikováno v:
Angewandte Chemie (International ed. in English). 58(50)
Most multi-action Pt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::566577ec57cacdfe9c6a8d4a1c59c87f
https://pubmed.ncbi.nlm.nih.gov/31599054
https://pubmed.ncbi.nlm.nih.gov/31599054
Publikováno v:
Journal of Chemical Sciences. 128:401-413
Certain nutrients viz., glucose and methionine are consumed more by cancer cells. Hence, an anticancer agent conjugated to them may render more toxicity in cancer cells due to higher uptake. To probe this effect, methionine and glucosamine were conju
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3af063a766915cb31965601681470bf3
https://doi.org/10.1007/s12039-015-1019-3
https://doi.org/10.1007/s12039-015-1019-3
Publikováno v:
Dalton Transactions. 45:3599-3615
A pyridine ring containing a chelating nitrogen mustard ligand bis(2-chloroethyl)pyridylmethylamine hydrochloride (L2·HCl) was synthesized from bis(2-hydroxyethyl)pyridylmethylamine (L1) on reaction with thionyl chloride. Both the ligands upon react
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aff2a4e64d20b0b786e1381f4637afb8
https://doi.org/10.1039/c5dt04459f
https://doi.org/10.1039/c5dt04459f